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Phenotypic heterogeneity is a strategy commonly used by bacteria to rapidly adapt to changing environmental conditions. Here, we study the interplay between phenotypic heterogeneity and genetic diversity in spatially extended populations.…

Populations and Evolution · Quantitative Biology 2014-09-05 Steffen Rulands , David Jahn , Erwin Frey

Organisms adapt to fluctuating environments by regulating their dynamics, and by adjusting their phenotypes to environmental changes. We model population growth using multitype branching processes in random environments, where the offspring…

Probability · Mathematics 2009-12-08 Clément Dombry , Christian Mazza , Vincent Bansaye

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Phenotypic heterogeneity along the epithelial-mesenchymal (E-M) axis contributes to cancer metastasis and drug resistance. Recent experimental efforts have collated detailed time-course data on the emergence and dynamics of E-M…

Analysis of PDEs · Mathematics 2023-09-19 Jules Guilberteau , Paras Jain , Mohit Kumar Jolly , Nastassia Pouradier Duteil , Camille Pouchol

1) Micro-evolutionary predictions are complicated by ecological feedbacks like density dependence, while ecological predictions can be complicated by evolutionary change. A widely used approach in micro-evolution, quantitative genetics,…

Populations and Evolution · Quantitative Biology 2015-09-07 Tim Coulson , Floriane Plard , Susanne Schindler , Arpat Ozgul , Jean-Michel Gaillard

We analyse the asymptotic behaviour of integro-differential equations modelling $N$ populations in interaction, all structured by different traits. Interactions are modelled by non-local terms involving linear combinations of the total…

Populations and Evolution · Quantitative Biology 2017-04-17 Camille Pouchol , Emmanuel Trélat

We study the effect that disturbances in the ecological landscape exert on the spatial distribution of a population that evolves according to the nonlocal FKPP equation. Using both numerical and analytical techniques, we explore the three…

Adaptation and Self-Organizing Systems · Physics 2021-07-12 Vivian Dornelas , Eduardo H. Colombo , Cristóbal López , Emilio Hernández-García , Celia Anteneodo

We introduce a stochastic individual model for the spatial behavior of an animal population of dispersive and competitive species, considering various kinds of biological effects, such as heterogeneity of environmental conditions, mutual…

Probability · Mathematics 2016-07-05 Joaquin Fontbona , Sylvie Méléard

The characterization of plasticity, robustness, and evolvability, an important issue in biology, is studied in terms of phenotypic fluctuations. By numerically evolving gene regulatory networks, the proportionality between the phenotypic…

Populations and Evolution · Quantitative Biology 2015-06-15 Kunihiko Kaneko

In ecology, species can mitigate their extinction risks in uncertain environments by diversifying individual phenotypes. This observation is quantified by the theory of bet-hedging, which provides a reason for the degree of phenotypic…

Populations and Evolution · Quantitative Biology 2019-06-19 Paula Villa Martín , Miguel A. Muñoz , Simone Pigolotti

Ecological and evolutionary dynamics have been historically regarded as unfolding at broadly separated timescales. However, these two types of processes are nowadays well documented to much more tightly than traditionally assumed,…

Populations and Evolution · Quantitative Biology 2021-11-17 José Camacho Mateu , Matteo Sireci , Miguel A. Muñoz

We consider populations structured by a phenotypic trait and a space variable, in a non-homogeneous environment. In the case of sex- ual populations, we are able to derive models close to existing mod- els in theoretical biology, from a…

Analysis of PDEs · Mathematics 2011-05-11 Sepideh Mirrahimi , Gael Raoul

The enigmatic stability of population oscillations within ecological systems is analyzed. The underlying mechanism is presented in the framework of two interacting species free to migrate between two spatial patches. It is shown that that…

Soft Condensed Matter · Physics 2015-06-25 Refael Abta , Marcello Schiffer , Nadav M. Shnerb

This paper introduces a variational formulation of natural selection, paying special attention to the nature of "things" and the way that different "kinds" of "things" are individuated from - and influence - each other. We use the Bayesian…

Populations and Evolution · Quantitative Biology 2023-07-05 Karl Friston , Daniel Ari Friedman , Axel Constant , V. Bleu Knight , Thomas Parr , John O. Campbell

We study the qualitative homogenization of second order viscous Hamilton-Jacobi equations in space-time stationary ergodic random environments. Assuming that the Hamiltonian is convex and superquadratic in the momentum variable (gradient)…

Analysis of PDEs · Mathematics 2017-02-07 Wenjia Jing , Panagiotis E. Souganidis , Hung V. Tran

This paper addresses the question of optimal phenotypic plasticity as a response to environmental fluctuations while optimizing the cost/benefit ratio, where the cost is energetic expense of plasticity, and benefit is fitness. The…

Populations and Evolution · Quantitative Biology 2012-11-12 Patrick Coquillard , Alexandre Muzy , Francine Diener

We are interested in the impact of natural selection in a prey-predator community. We introduce an individual-based model of the community that takes into account both prey and predator phenotypes. Our aim is to understand the phenotypic…

Populations and Evolution · Quantitative Biology 2015-02-19 Manon Costa , Céline Hauzy , Nicolas Loeuille , Sylvie Méléard

This paper is concerned with an integral equation that models discrete time dynamics of a population in a patchy landscape. The patches in the domain are reflected through the discontinuity of the kernel of the integral operator at a finite…

Analysis of PDEs · Mathematics 2022-07-26 Omar Abdul Halim , Mohammad El Smaily

Cryptic genetic sequences have attenuated effects on phenotypes. In the classic view, relaxed selection allows cryptic genetic diversity to build up across individuals in a population, providing alleles that may later contribute to…

Populations and Evolution · Quantitative Biology 2013-05-23 Etienne Rajon , Joanna Masel

In this work we consider an epidemic system modelling the evolution of a spore-producing pathogen within a multi-host population of plants. Here we focus our analysis on the study of the stationary states. We first discuss the existence of…

Analysis of PDEs · Mathematics 2020-08-03 Jean-Baptiste Burie , Arnaud Ducrot , Quentin Griette , Quentin Richard
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