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Deep neural networks have demonstrated promising potential for the field of medical image reconstruction. In this work, an MRI reconstruction algorithm, which is referred to as quantitative susceptibility mapping (QSM), has been developed…

Image and Video Processing · Electrical Eng. & Systems 2018-06-18 Jaeyeon Yoon , Enhao Gong , Itthi Chatnuntawech , Berkin Bilgic , Jingu Lee , Woojin Jung , Jingyu Ko , Hosan Jung , Kawin Setsompop , Greg Zaharchuk , Eung Yeop Kim , John Pauly , Jongho Lee

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing technique to extract the distribution of tissue susceptibilities, demonstrating significant potential in studying neurological diseases. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Min Li , Chen Chen , Zhuang Xiong , Ying Liu , Pengfei Rong , Shanshan Shan , Feng Liu , Hongfu Sun , Yang Gao

Quantitative susceptibility mapping (QSM) is a valuable magnetic resonance imaging (MRI) contrast mechanism that has demonstrated broad clinical applications. However, the image reconstruction of QSM is challenging due to its ill-posed…

Image and Video Processing · Electrical Eng. & Systems 2021-01-29 Yang Gao , Xuanyu Zhu , Bradford A. Moffat , Rebecca Glarin , Alan H. Wilman , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…

Medical Physics · Physics 2019-04-16 Juan Liu , Kevin M. Koch

Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to estimate local tissue susceptibility, which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue. QSM requires addressing a…

Medical Physics · Physics 2019-06-03 Juan Liu , Kevin M. Koch

Introduction: Quantitative Susceptibility Mapping (QSM) is generally acquired with full brain coverage, even though many QSM brain-iron studies focus on the deep grey matter (DGM) region only. Reducing the spatial coverage to the DGM…

Quantitative Methods · Quantitative Biology 2021-06-02 Xuanyu Zhu , Yang Gao , Feng Liu , Stuart Crozier , Hongfu Sun

Quantitative Susceptibility Mapping (QSM) is a new phase-based technique for quantifying magnetic susceptibility. The existing QSM reconstruction methods generally require complicated pre-processing on high-quality phase data. In this work,…

Image and Video Processing · Electrical Eng. & Systems 2021-01-13 Zhiyang Lu , Jun Li , Zheng Li , Hongjian He , Jun Shi

Quantitative susceptibility mapping (QSM) is a valuable MRI post-processing technique that quantifies the magnetic susceptibility of body tissue from phase data. However, the traditional QSM reconstruction pipeline involves multiple…

Image and Video Processing · Electrical Eng. & Systems 2022-06-27 Yang Gao , Zhuang Xiong , Amir Fazlollahi , Peter J Nestor , Viktor Vegh , Fatima Nasrallah , Craig Winter , G. Bruce Pike , Stuart Crozier , Feng Liu , Hongfu Sun

Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume…

Image and Video Processing · Electrical Eng. & Systems 2019-05-16 Hongjiang Wei , Steven Cao , Yuyao Zhang , Xiaojun Guan , Fuhua Yan , Kristen W. Yeom , Chunlei Liu

Quantitative susceptibility mapping (QSM) is a useful magnetic resonance imaging (MRI) technique which provides spatial distribution of magnetic susceptibility values of tissues. QSMs can be obtained by deconvolving the dipole kernel from…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Gyutaek Oh , Hyokyoung Bae , Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Quantitative Susceptibility Mapping (QSM) estimates tissue magnetic susceptibility distributions from Magnetic Resonance (MR) phase measurements by solving an ill-posed dipole inversion problem. Conventional single orientation QSM methods…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Kuo-Wei Lai , Manisha Aggarwal , Peter van Zijl , Xu Li , Jeremias Sulam

Quantitative susceptibility mapping (QSM) has gained broad interests in the field by extracting biological tissue properties, predominantly myelin, iron and calcium from magnetic resonance imaging (MRI) phase measurements in vivo. Thereby,…

Image and Video Processing · Electrical Eng. & Systems 2019-12-12 Woojin Jung , Steffen Bollmann , Jongho Lee

Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that estimates magnetic susceptibility of tissue from Larmor frequency offset measurements. The generation of QSM requires solving a challenging…

Medical Physics · Physics 2020-08-18 Juan Liu , Kevin M. Koch

Quantitative Susceptibility Mapping (QSM) can estimate the underlying tissue magnetic susceptibility and reveal pathology. Current deep-learning-based approaches to solve the QSM inverse problem are restricted on fixed image resolution.…

Medical Physics · Physics 2019-08-02 Juan Liu , Kevin M. Koch

Purpose: Quantitative Susceptibility Mapping (QSM) reconstruction is a challenging inverse problem driven by poor conditioning of the field to susceptibility transformation. State-of-art QSM reconstruction methods either suffer from image…

Medical Physics · Physics 2019-03-14 Juan Liu , Andrew S. Nencka , L. Tugan Muftuler , Brad Swearingen , Robin Karr , Kevin M. Koch

Magnetic Resonance Imaging (MRI) acquisitions require extensive scan times, limiting patient throughput and increasing susceptibility to motion artifacts. Accelerated parallel MRI techniques reduce acquisition time by undersampling k-space…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mingi Kang

This article provides recommendations for implementing quantitative susceptibility mapping (QSM) for clinical brain research. It is a consensus of the ISMRM Electro-Magnetic Tissue Properties Study Group. While QSM technical development…

Quantitative susceptibility mapping (QSM) is a powerful MRI technique that has shown great potential in quantifying tissue susceptibility in numerous neurological disorders. However, the intrinsic ill-posed dipole inversion problem greatly…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Yicheng Chen , Angela Jakary , Sivakami Avadiappan , Christopher P. Hess , Janine M. Lupo

Quantitative Susceptibility Mapping is a parametric imaging technique to estimate the magnetic susceptibilities of biological tissues from MRI phase measurements. This problem of estimating the susceptibility map is ill posed. Regularized…

Image and Video Processing · Electrical Eng. & Systems 2022-10-14 Arvind Balachandrasekaran , Davood Karimi , Camilo Jaimes , Ali Gholipour

Background: Quantitative susceptibility mapping (QSM) of the brain is an advanced MRI technique for assessing tissue characteristics based on magnetic susceptibility, which varies with the composition of the tissue, such as iron, calcium,…

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