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Understanding whether and how treatment effects vary across subgroups is crucial to inform clinical practice and recommendations. Accordingly, the assessment of heterogeneous treatment effects (HTE) based on pre-specified potential effect…

Methodology · Statistics 2023-12-04 Bryan S. Blette , Scott D. Halpern , Fan Li , Michael O. Harhay

Clinical decision support using data mining techniques offers more intelligent way to reduce the decision error in the last few years. However, clinical datasets often suffer from high missingness, which adversely impacts the quality of…

Machine Learning · Computer Science 2020-11-20 Xuetong Wu , Hadi Akbarzadeh Khorshidi , Uwe Aickelin , Zobaida Edib , Michelle Peate

Gaussian Mixture models (GMMs) are a powerful tool for clustering, classification and density estimation when clustering structures are embedded in the data. The presence of missing values can largely impact the GMMs estimation process,…

Machine Learning · Statistics 2020-06-05 Alessio Serafini , Thomas Brendan Murphy , Luca Scrucca

Standard approaches for variable selection in linear models are not tailored to deal properly with high-dimensional and incomplete data. Currently, methods dedicated to high-dimensional data handle missing values by ad-hoc strategies, like…

Methodology · Statistics 2021-06-09 Avner Bar-Hen , Vincent Audigier

We evaluate the performance of targeted maximum likelihood estimation (TMLE) for estimating the average treatment effect in missing data scenarios under varying levels of positivity violations. We employ model- and design-based simulations,…

Methodology · Statistics 2026-05-12 Christoph Wiederkehr , Christian Heumann , Michael Schomaker

Missing data is a pervasive problem in epidemiology, with multiple imputation (MI) a commonly used analysis method. MI is valid when data are missing at random (MAR). However, definitions of MAR with multiple incomplete variables are not…

Methodology · Statistics 2025-04-14 Paul Madley-Dowd , Rachael A. Hughes , Maya B. Mathur , Jon Heron , Kate Tilling

Multiple classifier system (MCS) has become a successful alternative for improving classification performance. However, studies have shown inconsistent results for different MCSs, and it is often difficult to predict which MCS algorithm…

Machine Learning · Computer Science 2019-08-01 Zhen Gao , Maryam Zand , Jianhua Ruan

Multiple imputation (MI) is a popular method for dealing with missing values. However, the suitable way for applying clustering after MI remains unclear: how to pool partitions? How to assess the clustering instability when data are…

Methodology · Statistics 2022-05-16 Vincent Audigier , Ndèye Niang

Imputation of missing values is a strategy for handling non-responses in surveys or data loss in measurement processes, which may be more effective than ignoring them. When the variable represents a count, the literature dealing with this…

Applications · Statistics 2020-07-31 Gilma Hernández-Herrera , Albert Navarro , David Moriña

Causal discovery algorithms estimate causal graphs from observational data. This can provide a valuable complement to analyses focussing on the causal relation between individual treatment-outcome pairs. Constraint-based causal discovery…

Methodology · Statistics 2021-08-31 Janine Witte , Ronja Foraita , Vanessa Didelez

Multiple imputation is a straightforward method for handling missing data in a principled fashion. This paper presents an overview of multiple imputation, including important theoretical results and their practical implications for…

Methodology · Statistics 2018-01-15 Jared S. Murray

Recently, deep neural networks have expanded the state-of-art in various scientific fields and provided solutions to long standing problems across multiple application domains. Nevertheless, they also suffer from weaknesses since their…

Machine Learning · Computer Science 2023-05-03 Felipe Kenji Nakano , Konstantinos Pliakos , Celine Vens

We investigate the fairness concerns of training a machine learning model using data with missing values. Even though there are a number of fairness intervention methods in the literature, most of them require a complete training set as…

Machine Learning · Computer Science 2022-04-15 Haewon Jeong , Hao Wang , Flavio P. Calmon

Missing values are pervasive in large-scale time-series data, posing challenges for reliable analysis and decision-making. Many neural architectures have been designed to model and impute the complex and heterogeneous missingness patterns…

Machine Learning · Computer Science 2026-02-26 Joseph Arul Raj , Linglong Qian , Zina Ibrahim

The treatment of missing data can be difficult in multilevel research because state-of-the-art procedures such as multiple imputation (MI) may require advanced statistical knowledge or a high degree of familiarity with certain statistical…

Computation · Statistics 2016-11-11 Simon Grund , Oliver Lüdtke , Alexander Robitzsch

Existing manifold learning methods are not appropriate for image retrieval task, because most of them are unable to process query image and they have much additional computational cost especially for large scale database. Therefore, we…

Computer Vision and Pattern Recognition · Computer Science 2018-04-04 Jian Xu , Chunheng Wang , Chengzuo Qi , Cunzhao Shi , Baihua Xiao

Multiple imputation (MI) is a technique especially designed for handling missing data in public-use datasets. It allows analysts to perform incomplete-data inference straightforwardly by using several already imputed datasets released by…

Methodology · Statistics 2022-01-03 Kin Wai Chan

Global optimization of decision trees is a long-standing challenge in combinatorial optimization, yet such models play an important role in interpretable machine learning. Although the problem has been investigated for several decades, only…

Machine Learning · Computer Science 2026-02-03 Jiancheng Tu , Wenqi Fan , Zhibin Wu

Targeted Maximum Likelihood Estimation (TMLE) is increasingly used for doubly robust causal inference, but how missing data should be handled when using TMLE with data-adaptive approaches is unclear. Based on the Victorian Adolescent Health…

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