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Protein design, a grand challenge of the day, involves optimization on a fitness landscape, and leading methods adopt a model-based approach where a model is trained on a training set (protein sequences and fitness) and proposes candidates…

Machine Learning · Computer Science 2024-07-01 Saba Ghaffari , Ehsan Saleh , Alexander G. Schwing , Yu-Xiong Wang , Martin D. Burke , Saurabh Sinha

We propose a new approach to safe variable preselection in high-dimensional penalized regression, such as the lasso. Preselection - to start with a manageable set of covariates - has often been implemented without clear appreciation of its…

Estimating probabilistic deformable template models is a new approach in the fields of computer vision and probabilistic atlases in computational anatomy. A first coherent statistical framework modelling the variability as a hidden random…

Computation · Statistics 2009-01-16 Stéphanie Allassonnière , Estelle Kuhn

Contrastively trained text-image models have the remarkable ability to perform zero-shot classification, that is, classifying previously unseen images into categories that the model has never been explicitly trained to identify. However,…

Model averaging, as an appealing ensemble technique, strategically integrates all valuable information from candidate models to construct fast and accurate prediction. Despite of having been widely practiced in many fields such as…

Methodology · Statistics 2026-03-17 Zhuang Yong , Lv Jing , Tingting Li

We introduce a very general method for sparse and large-scale variable selection. The large-scale regression settings is such that both the number of parameters and the number of samples are extremely large. The proposed method is based on…

Statistics Theory · Mathematics 2019-07-31 Jelena Bradic

The identification of latent mediator variables is typically conducted using standard structural equation models (SEMs). When SEM is applied to mediation analysis with a causal interpretation, valid inference relies on the strong assumption…

Methodology · Statistics 2025-10-02 Sofia Morelli , Roberto Faleh , Holger Brandt

Software fault prediction model are employed to optimize testing resource allocation by identifying fault-prone classes before testing phases. Several researchers' have validated the use of different classification techniques to develop…

Software Engineering · Computer Science 2017-04-17 Lov Kumar , Santanu Rath , Ashish Sureka

Learning algorithms that aggregate predictions from an ensemble of diverse base classifiers consistently outperform individual methods. Many of these strategies have been developed in a supervised setting, where the accuracy of each base…

Machine Learning · Statistics 2018-02-14 Mehmet Eren Ahsen , Robert Vogel , Gustavo Stolovitzky

Deep regression is an important problem with numerous applications. These range from computer vision tasks such as age estimation from photographs, to medical tasks such as ejection fraction estimation from echocardiograms for disease…

Computer Vision and Pattern Recognition · Computer Science 2023-02-16 Weihang Dai , Xiaomeng Li , Kwang-Ting Cheng

Medical imaging has witnessed remarkable progress but usually requires a large amount of high-quality annotated data which is time-consuming and costly to obtain. To alleviate this burden, semi-supervised learning has garnered attention as…

Computer Vision and Pattern Recognition · Computer Science 2023-07-24 Qingyue Wei , Lequan Yu , Xianhang Li , Wei Shao , Cihang Xie , Lei Xing , Yuyin Zhou

Advances in data collecting technologies in genomics have significantly increased the need for tools designed to study the genetic basis of many diseases. Effective statistical methods should excel in both prediction accuracy and biomarker…

Methodology · Statistics 2025-11-13 Anthony-Alexander Christidis , Stefan Van Aelst , Ruben Zamar

Tackling pattern recognition problems in areas such as computer vision, bioinformatics, speech or text recognition is often done best by taking into account task-specific statistical relations between output variables. In structured…

Machine Learning · Statistics 2016-03-14 Rein Houthooft , Filip De Turck

We study the problem of estimating a temporally varying coefficient and varying structure (VCVS) graphical model underlying nonstationary time series data, such as social states of interacting individuals or microarray expression profiles…

Machine Learning · Statistics 2010-12-21 Mladen Kolar , Eric P. Xing

In M-open problems where no true model can be conceptualized, it is common to back off from modeling and merely seek good prediction. Even in M-complete problems, taking a predictive approach can be very useful. Stacking is a model…

Statistics Theory · Mathematics 2016-02-17 Tri Le , Bertrand Clarke

A class of simultaneous equation models arise in the many domains where observed binary outcomes are themselves a consequence of the existing choices of of one of the agents in the model. These models are gaining increasing interest in the…

Econometrics · Economics 2025-12-30 Shakeeb Khan , Elie Tamer , Qingsong Yao

Standard multiple testing procedures are designed to report a list of discoveries, or suspected false null hypotheses, given the hypotheses' p-values or test scores. Recently there has been a growing interest in enhancing such procedures by…

Methodology · Statistics 2025-10-29 Jack Freestone , William Stafford Noble , Uri Keich

The typical multi-task learning methods for spatio-temporal data prediction involve low-rank tensor computation. However, such a method have relatively weak performance when the task number is small, and we cannot integrate it into…

Machine Learning · Computer Science 2019-10-14 Qichen Li , Jiaxin Pei , Jianding Zhang , Bo Han

Improvement of statistical learning models in order to increase efficiency in solving classification or regression problems is still a goal pursued by the scientific community. In this way, the support vector machine model is one of the…

Machine Learning · Statistics 2019-11-22 Anderson Ara , Mateus Maia , Samuel Macêdo , Francisco Louzada

In this paper, we present an efficient computational framework with the purpose of generating weighted pseudo-measurements to improve the quality of Distribution System State Estimation (DSSE) and provide observability with Advanced…

Systems and Control · Computer Science 2019-01-23 Kaveh Dehghanpour , Yuxuan Yuan , Zhaoyu Wang , Fankun Bu