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Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Robust and accurate detection and segmentation of heterogenous tumors appearing in different anatomical organs with supervised methods require large-scale labeled datasets covering all possible types of diseases. Due to the unavailability…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Mehdi Astaraki , Francesca De Benetti , Yousef Yeganeh , Iuliana Toma-Dasu , Örjan Smedby , Chunliang Wang , Nassir Navab , Thomas Wendler

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Semi-supervised learning has attracted much attention in medical image segmentation due to challenges in acquiring pixel-wise image annotations, which is a crucial step for building high-performance deep learning methods. Most existing…

Computer Vision and Pattern Recognition · Computer Science 2020-10-22 Shuailin Li , Chuyu Zhang , Xuming He

Detecting novel anomalies in medical imaging is challenging due to the limited availability of labeled data for rare abnormalities, which often display high variability and subtlety. This challenge is further compounded when small abnormal…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Jingkun Chen , Guang Yang , Xiao Zhang , Jingchao Peng , Tianlu Zhang , Jianguo Zhang , Jungong Han , Vicente Grau

We focus on a specific use case in anomaly detection where the distribution of normal samples is supported by a lower-dimensional manifold. Here, regularized autoencoders provide a popular approach by learning the identity mapping on the…

Computer Vision and Pattern Recognition · Computer Science 2024-05-14 Alexander Bauer , Shinichi Nakajima , Klaus-Robert Müller

Unsupervised anomaly detection (UAD) based on deep generative modelling has been increasingly explored for identifying pathological brain abnormalities without requiring voxel-level annotations. By learning the distribution of healthy…

Computer Vision and Pattern Recognition · Computer Science 2026-03-10 Youwan Mahé , Elise Bannier , Stéphanie Leplaideur , Elisa Fromont , Francesca Galassi

Fully supervised segmentation methods require a large training cohort of already segmented images, providing information at the pixel level of each image. We present a method to automatically segment and model pathologies in medical images,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Simon Andermatt , Antal Horváth , Simon Pezold , Philippe Cattin

Harnessing the power of deep neural networks in the medical imaging domain is challenging due to the difficulties in acquiring large annotated datasets, especially for rare diseases, which involve high costs, time, and effort for…

Image and Video Processing · Electrical Eng. & Systems 2023-08-22 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd J. Schwedt , Gina Dumkrieger , Simona Nikolova , Baoxin Li

Unsupervised anomaly detection (UAD) methods are trained with normal (or healthy) images only, but during testing, they are able to classify normal and abnormal (or disease) images. UAD is an important medical image analysis (MIA) method to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Yu Tian , Fengbei Liu , Guansong Pang , Yuanhong Chen , Yuyuan Liu , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro

Unsupervised anomaly detection and segmentation methods train a model to learn the training distribution as `normal'. In the testing phase, they identify patterns that deviate from this normal distribution as `anomalies'. To learn the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Ziyun Liang , Xiaoqing Guo , Wentian Xu , Yasin Ibrahim , Natalie Voets , Pieter M Pretorius , J. Alison Noble , Konstantinos Kamnitsas

The detection and localization of anomalies is one important medical image analysis task. Most commonly, Computer Vision anomaly detection approaches rely on manual annotations that are both time consuming and expensive to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Sergio Naval Marimont , Giacomo Tarroni

Anomaly segmentation in high spatial resolution (HSR) remote sensing imagery is aimed at segmenting anomaly patterns of the earth deviating from normal patterns, which plays an important role in various Earth vision applications. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-05-01 Jingtao Li , Xinyu Wang , Hengwei Zhao , Shaoyu Wang , Yanfei Zhong

Automated anomaly detection from medical images, such as MRIs and X-rays, can significantly reduce human effort in disease diagnosis. Owing to the complexity of modeling anomalies and the high cost of manual annotation by domain experts…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Md Mahfuzur Rahman Siddiquee , Jay Shah , Teresa Wu , Catherine Chong , Todd Schwedt , Baoxin Li

Early and accurate disease detection is crucial for patient management and successful treatment outcomes. However, the automatic identification of anomalies in medical images can be challenging. Conventional methods rely on large labeled…

Image and Video Processing · Electrical Eng. & Systems 2023-03-16 Cosmin I Bercea , Benedikt Wiestler , Daniel Rueckert , Julia A Schnabel

Automated nodule segmentation is essential for computer-assisted diagnosis in ultrasound images. Nevertheless, most existing methods depend on precise pixel-level annotations by medical professionals, a process that is both costly and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Xingyue Zhao , Peiqi Li , Xiangde Luo , Meng Yang , Shi Chang , Zhongyu Li

Anomalies are by definition rare, thus labeled examples are very limited or nonexistent, and likely do not cover unforeseen scenarios. Unsupervised learning methods that don't necessarily encounter anomalies in training would be immensely…

Computer Vision and Pattern Recognition · Computer Science 2020-06-23 Louise Naud , Alexander Lavin

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers

Image segmentation, the process of partitioning an image into meaningful regions, plays a pivotal role in computer vision and medical imaging applications. Unsupervised segmentation, particularly in the absence of labeled data, remains a…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Kovvuri Sai Gopal Reddy , Bodduluri Saran , A. Mudit Adityaja , Saurabh J. Shigwan , Nitin Kumar

Ultrasound imaging is challenging to interpret due to non-uniform intensities, low contrast, and inherent artifacts, necessitating extensive training for non-specialists. Advanced representation with clear tissue structure separation could…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Oleksandra Tmenova , Yordanka Velikova , Mahdi Saleh , Nassir Navab