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Multiple instance learning (MIL) is a powerful approach to classify whole slide images (WSIs) for diagnostic pathology. A fundamental challenge of MIL on WSI classification is to discover the \textit{critical instances} that trigger the bag…

Computer Vision and Pattern Recognition · Computer Science 2022-09-02 Zhikang Wang , Yue Bi , Tong Pan , Xiaoyu Wang , Chris Bain , Richard Bassed , Seiya Imoto , Jianhua Yao , Jiangning Song

We present a weakly supervised deep learning method to perform instance segmentation of cells present in microscopy images. Annotation of biomedical images in the lab can be scarce, incomplete, and inaccurate. This is of concern when…

Computer Vision and Pattern Recognition · Computer Science 2019-08-28 Fidel A. Guerrero-Peña , Pedro D. Marrero Fernandez , Tsang Ing Ren , Alexandre Cunha

Despite the rapid advance of unsupervised anomaly detection, existing methods require to train separate models for different objects. In this work, we present UniAD that accomplishes anomaly detection for multiple classes with a unified…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Zhiyuan You , Lei Cui , Yujun Shen , Kai Yang , Xin Lu , Yu Zheng , Xinyi Le

Bag-based Multiple Instance Learning (MIL) approaches have emerged as the mainstream methodology for Whole Slide Image (WSI) classification. However, most existing methods adopt a segmented training strategy, which first extracts features…

Computer Vision and Pattern Recognition · Computer Science 2025-03-13 Jiangping Wen , Jinyu Wen , Meie Fang

Quantitative medical image computing (radiomics) has been widely applied to build prediction models from medical images. However, overfitting is a significant issue in conventional radiomics, where a large number of radiomic features are…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Jianan Chen , Laurent Milot , Helen M. C. Cheung , Anne L. Martel

We introduce CASED, a novel curriculum sampling algorithm that facilitates the optimization of deep learning segmentation or detection models on data sets with extreme class imbalance. We evaluate the CASED learning framework on the task of…

Computer Vision and Pattern Recognition · Computer Science 2018-07-31 Andrew Jesson , Nicolas Guizard , Sina Hamidi Ghalehjegh , Damien Goblot , Florian Soudan , Nicolas Chapados

Class imbalance significantly impacts the performance of multi-label classifiers. Oversampling is one of the most popular approaches, as it augments instances associated with less frequent labels to balance the class distribution. Existing…

Machine Learning · Computer Science 2024-08-26 Ao Zhou , Bin Liu , Jin Wang , Kaiwei Sun , Kelin Liu

Anomaly detection is a critical task in computer vision with profound implications for medical imaging, where identifying pathologies early can directly impact patient outcomes. While recent unsupervised anomaly detection approaches show…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Le Dong , Qinzhong Tan , Chunlei Li , Jingliang Hu , Yilei Shi , Weisheng Dong , Xiao Xiang Zhu , Lichao Mou

Anomaly detection (AD) plays an important role in various real-world applications. Recent advancements in AD, however, are often biased towards industrial inspection, struggle to generalize to broader tasks like semantic anomaly detection…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Hangil Park , Yongmin Seo , Tae-Kyun Kim

In order to improve model accuracy, generalization, and class imbalance issues, this work offers a strong methodology for classifying endoscopic images. We suggest a hybrid feature extraction method that combines convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Bidisha Chakraborty , Shree Mitra

Reliably detecting anomalies in a given set of images is a task of high practical relevance for visual quality inspection, surveillance, or medical image analysis. Autoencoder neural networks learn to reconstruct normal images, and hence…

Machine Learning · Computer Science 2019-01-21 Laura Beggel , Michael Pfeiffer , Bernd Bischl

The latest trend in anomaly detection is to train a unified model instead of training a separate model for each category. However, existing multi-class anomaly detection (MCAD) models perform poorly in multi-view scenarios because they…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Qianzi Yu , Yang Cao , Yu Kang

In industry, machine anomalous sound detection (ASD) is in great demand. However, collecting enough abnormal samples is difficult due to the high cost, which boosts the rapid development of unsupervised ASD algorithms. Autoencoder (AE)…

Sound · Computer Science 2023-11-16 Yifan Zhou , Dongxing Xu , Haoran Wei , Yanhua Long

Target imbalance affects the performance of recent deep learning methods in many medical image segmentation tasks. It is a twofold problem: class imbalance - positive class (lesion) size compared to negative class (non-lesion) size; lesion…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Boris Shirokikh , Alexey Shevtsov , Anvar Kurmukov , Alexandra Dalechina , Egor Krivov , Valery Kostjuchenko , Andrey Golanov , Mikhail Belyaev

This paper proposes an autoencoder (AE) that is used for improving the performance of once-class classifiers for the purpose of detecting anomalies. Traditional one-class classifiers (OCCs) perform poorly under certain conditions such as…

Machine Learning · Computer Science 2020-01-01 Kasra Babaei , ZhiYuan Chen , Tomas Maul

We consider machine-learning-based thyroid-malignancy prediction from cytopathology whole-slide images (WSI). Multiple instance learning (MIL) approaches, typically used for the analysis of WSIs, divide the image (bag) into patches…

Anomaly detection based on one-class classification algorithms is broadly used in many applied domains like image processing (e.g. detection of whether a patient is "cancerous" or "healthy" from mammography image), network intrusion…

Machine Learning · Statistics 2017-07-14 Evgeny Burnaev , Pavel Erofeev , Dmitry Smolyakov

In this paper we develop a new unsupervised machine learning technique comprised of a feature extractor, a convolutional autoencoder (CAE), and a clustering algorithm consisting of a Bayesian Gaussian mixture model (BGM). We apply this…

Instrumentation and Methods for Astrophysics · Physics 2020-04-15 Ting-Yun Cheng , Nan Li , Christopher J. Conselice , Alfonso Aragón-Salamanca , Simon Dye , Robert B. Metcalf

Purpose: To design multi-disease classifiers for body CT scans for three different organ systems using automatically extracted labels from radiology text reports.Materials & Methods: This retrospective study included a total of 12,092…

Computer Vision and Pattern Recognition · Computer Science 2021-12-07 Fakrul Islam Tushar , Vincent M. D'Anniballe , Rui Hou , Maciej A. Mazurowski , Wanyi Fu , Ehsan Samei , Geoffrey D. Rubin , Joseph Y. Lo

Preventable or undiagnosed visual impairment and blindness affect billion of people worldwide. Automated multi-disease detection models offer great potential to address this problem via clinical decision support in diagnosis. In this work,…

Image and Video Processing · Electrical Eng. & Systems 2021-03-30 Dominik Müller , Iñaki Soto-Rey , Frank Kramer