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Given their increasing participation in fast-changing markets, the integration of scheduling and control is an important consideration in chemical process operations. This generally involves computing optimal production schedules using…

Optimization and Control · Mathematics 2020-05-19 Calvin Tsay , Michael Baldea

We present a new application of model checking which achieves real-time multi-step planning and obstacle avoidance on a real autonomous robot. We have developed a small, purpose-built model checking algorithm which generates plans in situ…

Robotics · Computer Science 2025-08-27 Christopher Chandler , Bernd Porr , Giulia Lafratta , Alice Miller

The ability to predict accurate thermodynamic and kinetic properties in biomolecular systems is of both scientific and practical utility. While both remain very difficult, predictions of kinetics are particularly difficult because rates, in…

Chemical Physics · Physics 2018-06-13 Yong Wang , Omar Valsson , Pratyush Tiwary , Michele Parrinello , Kresten Lindorff-Larsen

A general scheme, which includes constructions of coarse-grained (CG) models, weighted ensemble dynamics (WED) simulations and cluster analyses (CA) of stable states, is presented to detect dynamical and thermodynamical properties in…

Soft Condensed Matter · Physics 2008-12-04 Xin Zhou

Knowledge Distillation (KD) has emerged as a promising technique for model compression but faces critical limitations: (1) sensitivity to hyperparameters requiring extensive manual tuning, (2) capacity gap when distilling from very large…

Machine Learning · Computer Science 2025-12-11 Gustavo Coelho Haase , Paulo Henrique Dourado da Silva

Once trained, machine-learned interatomic potentials (MLIPs) provide a fast and accurate way to study catalytic reaction pathways, but their performance strongly depends on the training set. Here, we compare nine MLIPs trained with…

Fuels with high-knock resistance enable modern spark-ignition engines to achieve high efficiency and thus low CO2 emissions. Identification of molecules with desired autoignition properties indicated by a high research octane number and a…

Metaheuristic algorithms, widely used for solving complex non-convex and non-differentiable optimization problems, often lack a solid mathematical foundation. In this review, we explore how concepts and methods from kinetic theory can offer…

Optimization and Control · Mathematics 2024-10-15 Giacomo Borghi , Michael Herty , Lorenzo Pareschi

Molecular dynamics (MD) simulation is applied to the condensation process of supersaturated vapors of methane, ethane, and carbon dioxide. Simulations of systems with up to a million particles were conducted with a massively parallel MD…

A sizable part of the fleet of heavy-duty machinery in the construction equipment industry uses the conventional valve-controlled load-sensing hydraulics. Rigorous climate actions towards reducing CO$_{2}$ emissions has sparked the…

Systems and Control · Electrical Eng. & Systems 2023-08-01 Abdolreza Taheri , Robert Pettersson , Pelle Gustafsson , Joni Pajarinen , Reza Ghabcheloo

We introduce the optimized dynamic mode decomposition algorithm for constructing an adaptive and computationally efficient reduced order model and forecasting tool for global atmospheric chemistry dynamics. By exploiting a low-dimensional…

Machine Learning · Computer Science 2024-04-22 Meghana Velegar , Christoph Keller , J. Nathan Kutz

We demonstrate transfer learning capabilities in a machine-learned algorithm trained for particle-flow reconstruction in high energy particle colliders. This paper presents a cross-detector fine-tuning study, where we initially pretrain the…

High Energy Physics - Experiment · Physics 2025-06-26 Farouk Mokhtar , Joosep Pata , Dolores Garcia , Eric Wulff , Mengke Zhang , Michael Kagan , Javier Duarte

In this study, deep learning is used to estimate kinetic parameters for modeling itaconic acid production based on real batch experiments conducted at different agitation speeds and reactor scales. Two deep learning strategies, namely…

Machine Learning · Computer Science 2026-04-27 Daria Fokina , Marco Baldan , Constantin Romankiewicz , Wolfgang Laudensack , Roland Ulber , Michael Bortz

Efficient chemical kinetic model inference and application in combustion are challenging due to large ODE systems and widely separated time scales. Machine learning techniques have been proposed to streamline these models, though strong…

Machine Learning · Computer Science 2025-08-27 Benjamin C. Koenig , Suyong Kim , Sili Deng

Detailed dynamical systems models used in life sciences may include dozens or even hundreds of state variables. Models of large dimension are not only harder from the numerical perspective (e.g., for parameter estimation or simulation), but…

Quantitative Methods · Quantitative Biology 2022-07-06 Antonio Jiménez-Pastor , Joshua Paul Jacob , Gleb Pogudin

Computational studies of chemical reactions in complex environments such as proteins, nanostructures, or on surfaces require accurate and efficient atomistic models applicable to the nanometer scale. In general, an accurate parametrization…

Chemical Physics · Physics 2020-02-18 Christoph Brunken , Markus Reiher

In this work, we address the challenge of efficiently modeling dynamical systems in process engineering. We use reduced-order model learning, specifically operator inference. This is a non-intrusive, data-driven method for learning…

Numerical Analysis · Mathematics 2024-07-31 Ion Victor Gosea , Luisa Peterson , Pawan Goyal , Jens Bremer , Kai Sundmacher , Peter Benner

Computer-Aided Design (CAD) is essential in industrial design, but the complexity of traditional CAD modeling and workflows presents significant challenges for automating the generation of high-precision, editable CAD models. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Ke Niu , Haiyang Yu , Zhuofan Chen , Zhengtao Yao , Weitao Jia , Xiaodong Ge , Jingqun Tang , Benlei Cui , Bin Li , Xiangyang Xue

Accurate simulations of combustion phenomena require the use of detailed chemical kinetics in order to capture limit phenomena such as ignition and extinction as well as predict pollutant formation. However, the chemical kinetic models for…

Computational Physics · Physics 2017-03-31 Kyle E. Niemeyer , Nicholas J. Curtis , Chih-Jen Sung

Controlling polymorphism in molecular crystals is crucial in the pharmaceutical, dye, and pesticide industries. However, its theoretical description is extremely challenging, due to the associated long timescales ($ > 1 \, \mu s$). We…

Chemical Physics · Physics 2023-02-09 Oren Elishav , Roy Podgaetsky , Olga Meikler , Barak Hirshberg
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