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The control of biofilm formation is a challenging goal that has not been reached yet in many aspects. One is the role of van der Waals forces and another the importance of mutual interactions between the adsorbing and the adsorbed…

Soft Condensed Matter · Physics 2019-08-12 Y. Schmitt , H. Hähl , C. Gilow , H. Mantz , K. Jacobs , O. Leidinger , M. Bellion , L. Santen

There is significant interest in modelling the mechanics and physics of growth of soft biological systems such as tumors and bacterial biofilms. Solid tumors account for more than 85% of cancer mortality and bacterial biofilms account for a…

Soft Condensed Matter · Physics 2024-03-29 Chockalingam Senthilnathan , Tal Cohen

Biofilms are complex structures which are inhabited by numerous amount of different species of microorganisms. Due to their ubiquity, they influence human life on an everyday basis. It is therefore important to understand the interactions…

Computational Engineering, Finance, and Science · Computer Science 2025-09-03 Felix Klempt , Hendrik Geisler , Meisam Soleimani , Philipp Junker

Controlling bacterial surface adhesion and subsequent biofilm formation in fluid systems is crucial for the safety and efficacy of medical and industrial processes. Here, we theoretically examine the transport of bacteria close to surfaces,…

Soft Condensed Matter · Physics 2025-07-08 Edwina F. Yeo , Benjamin J. Walker , Philip Pearce , Mohit P. Dalwadi

Mechanical stresses stemming from environmental factors are a key determinant of cellular behavior and physiology. Yet, the role of self-induced biomechanical stresses in growing bacterial colonies has remained largely unexplored. Here, we…

Soft Condensed Matter · Physics 2023-11-27 René Wittmann , G. H. Philipp Nguyen , Hartmut Löwen , Fabian J. Schwarzendahl , Anupam Sengupta

To provide insight into the basic properties of emerging structures when bacteria or other microorganisms conquer surfaces, it is crucial to analyze their growth behavior during the formation of thin films. In this regard, many theoretical…

Soft Condensed Matter · Physics 2025-05-23 Yuta Kuroda , Takeshi Kawasaki , Andreas M. Menzel

Pentacene is known to grow on isotropic silicon oxide surfaces in a substrate-induced phase with fiber textured crystallites. This growth study reports on the growth of pentacene crystallites on uniaxially oriented surfaces. Silica…

Materials Science · Physics 2022-07-12 Stefan Pachmajer , Oliver Werzer , Carlo Mennucci , Francesco Buatier de Mongeot , R. Resel

Densely packed, motile bacteria can adopt collective states not seen in conventional, passive materials. These states remain in many ways mysterious, and their physical characterization can aid our understanding of natural bacterial…

Statistical Mechanics · Physics 2024-06-18 Hisay Lama , Masahiro J. Yamamoto , Yujiro Furuta , Takuro Shimaya , Kazumasa A. Takeuchi

Bacteria frequently colonize natural microcavities such as gut crypts, plant apoplasts, and soil pores. Recent studies have shown that the physical structure of these spaces plays a crucial role in shaping the stability and resilience of…

Populations and Evolution · Quantitative Biology 2025-03-28 Valentin Slepukhin , Víctor Peris Yagüe , Christian Westendorf , Birgit Koch , Oskar Hallatschek

The extracellular matrix of biofilms presents a dense and intricate architecture. Numerous biophysical properties of the matrix surrounding microbial cells contribute to the heterogeneity of biofilms and their functions at the microscale.…

Biomolecules · Quantitative Biology 2025-10-24 Raghu K. Moorthy , Eoin Casey

Anaerobic processes (e.g., methanogenesis and fermentation) largely contribute to element cycling and natural contaminant attenuation/mobilization, even in well-oxygenated porous environments, such as shallow aquifers. This paradox is…

Biological Physics · Physics 2022-11-24 Giulia Ceriotti , Sergey M. Borisov , Jasmine Berg , Pietro de Anna

The goal of this work is to develop a numerical simulation that accurately captures the biomechanical response of bacterial biofilms and their associated extracellular matrix (ECM). In this, the second of a two-part effort, the primary…

Electrochemical communication is a mechanism that enables intercellular interaction among bacteria within communities. Bacteria achieves synchronization and coordinates collective actions at the population level through the utilization of…

Information Theory · Computer Science 2024-03-15 Nithin V. Sabu , Bige Deniz Unluturk

We perform mathematical anaysis of the biofilm development process. A model describing biomass growth is proposed: It arises from coupling three parabolic nonlinear equations: a biomass equation with degenerate and singular diffusion, a…

Analysis of PDEs · Mathematics 2017-03-14 Maria Gokieli , Nobuyuki Kenmochi , Marek Niezgódka

Biological evolution of a population is governed by the fitness landscape, which is a map from genotype to fitness. However, a fitness landscape depends on the organisms environment, and evolution in changing environments is still poorly…

Populations and Evolution · Quantitative Biology 2022-09-26 Suman G Das , Joachim Krug , Muhittin Mungan

Immotile microbes inhabit nearly every environment on Earth, from soils and sediments to food matrices -- yet how they disperse through these physically confining environments is poorly understood. Here, we show that immotile microbial…

Microbes thrive in diverse porous environments -- from soil and riverbeds to human lungs and cancer tissues -- spanning multiple scales and conditions. Short- to long-term fluctuations in local factors induce spatio-temporal…

Biological Physics · Physics 2024-04-22 Chenyu Jin , Anupam Sengupta

Periodic wrinkling of a rigid capping layer on a deformable substrate provides a useful method for templating surface topography for a variety of novel applications. Many experiments have studied wrinkle formation during the compression of…

Soft Condensed Matter · Physics 2020-04-21 John F. Niven , Gurkaran Chowdhry , James S. Sharp , Kari Dalnoki-Veress

A number of recent experiments have showed that surfactants can modify the growth mode of an epitaxial film, suppressing islanding and promoting layer-by-layer growth. Here a set of coupled equations are introduced to describe the coupling…

Condensed Matter · Physics 2016-11-03 Albert-Laszlo Barabasi

This fluid dynamics video presents three-dimensional kinetic simulations of the dynamics in suspensions of oxytactic bacteria confined in thin liquid film surrounded by air. At the initial time, the bacterial concentration is uniform and…

Fluid Dynamics · Physics 2011-10-17 Barath Ezhilan , Amir Alizadeh Pahlavan , David Saintillan