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Traditional multimodal learners find unified representations for tasks like visual question answering, but rely heavily on paired datasets. However, an overlooked yet potentially powerful question is: can one leverage auxiliary unpaired…

Machine Learning · Computer Science 2025-10-10 Sharut Gupta , Shobhita Sundaram , Chenyu Wang , Stefanie Jegelka , Phillip Isola

Deep learning has brought significant progress to medical image classification, yet most existing methods still rely on isolated visual evidence and cannot effectively leverage similar cases or external knowledge. In clinical practice,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-28 Yiming Xu , Yixuan Liu , Yuhang Zhang , Ling Zheng , Yihan Wang , Qi Song

A fundamental feature of human intelligence is the ability to infer high-level abstractions from low-level sensory data. An essential component of such inference is the ability to discover modularized generative mechanisms. Despite many…

Machine Learning · Computer Science 2023-06-08 Peyman Sheikholharam Mashhadi , Slawomir Nowaczyk

Deep learning (DL) methods have in recent years yielded impressive results in medical imaging, with the potential to function as clinical aid to radiologists. However, DL models in medical imaging are often trained on public research…

Early forecasting of individual cognitive decline in Alzheimer's disease (AD) is central to disease evaluation and management. Despite advances, it is as of yet challenging for existing methodological frameworks to integrate multimodal data…

We explore three representative lines of research and demonstrate the utility of our methods on a classification benchmark of brain cancer MRI data. First, we present a capsule network that explicitly learns a representation robust to…

Image and Video Processing · Electrical Eng. & Systems 2020-05-13 Neil Getty , Thomas Brettin , Dong Jin , Rick Stevens , Fangfang Xia

Deep learning is attracting significant interest in the neuroimaging community as a means to diagnose psychiatric and neurological disorders from structural magnetic resonance images. However, there is a tendency amongst researchers to…

Machine Learning · Computer Science 2019-10-22 David Wood , James Cole , Thomas Booth

Multimodal representation learning aims to capture both shared and complementary semantic information across multiple modalities. However, the intrinsic heterogeneity of diverse modalities presents substantial challenges to achieve…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Chengxuan Qian , Shuo Xing , Shawn Li , Yue Zhao , Zhengzhong Tu

Multimodal medical image fusion is a crucial task that combines complementary information from different imaging modalities into a unified representation, thereby enhancing diagnostic accuracy and treatment planning. While deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Meng Zhou , Yuxuan Zhang , Xiaolan Xu , Jiayi Wang , Farzad Khalvati

Multimodal image registration is a challenging but essential step for numerous image-guided procedures. Most registration algorithms rely on the computation of complex, frequently non-differentiable similarity metrics to deal with the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Matteo Ronchetti , Wolfgang Wein , Nassir Navab , Oliver Zettinig , Raphael Prevost

In this paper, an innovative multi-modal deep learning model is proposed to deeply integrate heterogeneous information from medical images and clinical reports. First, for medical images, convolutional neural networks were used to extract…

Machine Learning · Computer Science 2024-05-29 Ziyan Yao , Fei Lin , Sheng Chai , Weijie He , Lu Dai , Xinghui Fei

Alzheimer's disease is a major cause of dementia. Its diagnosis requires accurate biomarkers that are sensitive to disease stages. In this respect, we regard probabilistic classification as a method of designing a probabilistic biomarker…

Machine Learning · Computer Science 2017-06-06 Murat Seckin Ayhan , Vijay Raghavan , Alzheimer's disease Neuroimaging Initiative

Retinal diseases spanning a broad spectrum can be effectively identified and diagnosed using complementary signals from multimodal data. However, multimodal diagnosis in ophthalmic practice is typically challenged in terms of data…

Computer Vision and Pattern Recognition · Computer Science 2026-02-04 Lu Zhang , Huizhen Yu , Zuowei Wang , Fu Gui , Yatu Guo , Wei Zhang , Mengyu Jia

In this paper, the problem of orientation correction in cardiac MRI images is investigated and a framework for orientation recognition via deep neural networks is proposed. For multi-modality MRI, we introduce a transfer learning strategy…

Image and Video Processing · Electrical Eng. & Systems 2022-11-22 Jiyao Liu

Deformable registration is one of the most challenging task in the field of medical image analysis, especially for the alignment between different sequences and modalities. In this paper, a non-rigid registration method is proposed for 3D…

Computer Vision and Pattern Recognition · Computer Science 2020-02-27 Xiaoyue Zhang , Weijian Jian , Yu Chen , Shihting Yang

Interpretability is crucial to enhance trust in machine learning models for medical diagnostics. However, most state-of-the-art image classifiers based on neural networks are not interpretable. As a result, clinicians often resort to known…

Deep learning has been recently used for the analysis of neuroimages, such as structural magnetic resonance imaging (MRI), functional MRI, and positron emission tomography (PET), and has achieved significant performance improvements over…

Image and Video Processing · Electrical Eng. & Systems 2020-05-12 Li Zhang , Mingliang Wang , Mingxia Liu , Daoqiang Zhang

Multimodal medical imaging plays a pivotal role in clinical diagnosis and research, as it combines information from various imaging modalities to provide a more comprehensive understanding of the underlying pathology. Recently, deep…

Computer Vision and Pattern Recognition · Computer Science 2024-04-24 Yihao Li , Mostafa El Habib Daho , Pierre-Henri Conze , Rachid Zeghlache , Hugo Le Boité , Ramin Tadayoni , Béatrice Cochener , Mathieu Lamard , Gwenolé Quellec

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Deep learning and multi-modal fusion have demonstrated transformative potential in medical diagnosis by integrating diverse data sources. However, accurate prognosis for ischemic stroke remains challenging due to limitations in existing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Liren Chen , Lidong Sun , Mingyan Huang , Junzhe Tang , Yinghui Zhu , Guanjie Wang , Yiqing Xia , Ting Xiao