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We currently observe a disconcerting phenomenon in machine learning studies in psychiatry: While we would expect larger samples to yield better results due to the availability of more data, larger machine learning studies consistently show…

The success of Deep Neural Network (DNN) models significantly depends on the quality of provided annotations. In medical image segmentation, for example, having multiple expert annotations for each data point is common to minimize…

Computer Vision and Pattern Recognition · Computer Science 2025-02-12 Asma Ahmed Hashmi , Aigerim Zhumabayeva , Nikita Kotelevskii , Artem Agafonov , Mohammad Yaqub , Maxim Panov , Martin Takáč

Besides serving as prediction models, classification trees are useful for finding important predictor variables and identifying interesting subgroups in the data. These functions can be compromised by weak split selection algorithms that…

Applications · Statistics 2010-11-03 Wei-Yin Loh

Randomized Controlled Trials (RCTs) represent a gold standard when developing policy guidelines. However, RCTs are often narrow, and lack data on broader populations of interest. Causal effects in these populations are often estimated using…

Machine Learning · Computer Science 2023-03-07 Zeshan Hussain , Michael Oberst , Ming-Chieh Shih , David Sontag

Data analysis and machine learning have become an integrative part of the modern scientific methodology, offering automated procedures for the prediction of a phenomenon based on past observations, unraveling underlying patterns in data and…

Machine Learning · Statistics 2015-06-04 Gilles Louppe

Clinical time series data are critical for patient monitoring and predictive modeling. These time series are typically multivariate and often comprise hundreds of heterogeneous features from different data sources. The grouping of features…

Machine Learning · Computer Science 2025-11-12 Fedor Sergeev , Manuel Burger , Polina Leshetkina , Vincent Fortuin , Gunnar Rätsch , Rita Kuznetsova

Robust estimation of heterogeneous treatment effects is a fundamental challenge for optimal decision-making in domains ranging from personalized medicine to educational policy. In recent years, predictive machine learning has emerged as a…

Machine Learning · Statistics 2025-06-23 Maximilian Schuessler , Erik Sverdrup , Robert Tibshirani

Machine learning models are often criticized for their black-box nature, raising concerns about their applicability in critical decision-making scenarios. Consequently, there is a growing demand for interpretable models in such contexts. In…

Machine Learning · Computer Science 2024-08-28 I-Ling Cheng , Chan Hsu , Chantung Ku , Pei-Ju Lee , Yihuang Kang

Randomized controlled trials (RCTs) serve as the cornerstone for understanding causal effects, yet extending inferences to target populations presents challenges due to effect heterogeneity and underrepresentation. Our paper addresses the…

Methodology · Statistics 2025-05-19 Harsh Parikh , Rachael Ross , Elizabeth Stuart , Kara Rudolph

Recently, deep learning models have been widely applied in program understanding tasks, and these models achieve state-of-the-art results on many benchmark datasets. A major challenge of deep learning for program understanding is that the…

Software Engineering · Computer Science 2024-01-02 Wenhan Wang , Yanzhou Li , Anran Li , Jian Zhang , Wei Ma , Yang Liu

The field of information retrieval often works with limited and noisy data in an attempt to classify documents into subjective categories, e.g., relevance, sentiment and controversy. We typically quantify a notion of agreement to understand…

Information Retrieval · Computer Science 2018-06-14 John Foley

Deep learning models have demonstrated promising results in estimating treatment effects (TEE). However, most of them overlook the variations in treatment outcomes among subgroups with distinct characteristics. This limitation hinders their…

Machine Learning · Computer Science 2024-01-31 Seungyeon Lee , Ruoqi Liu , Wenyu Song , Ping Zhang

When analyzing the behavior of machine learning algorithms, it is important to identify specific data subgroups for which the considered algorithm shows different performance with respect to the entire dataset. The intervention of domain…

Machine Learning · Computer Science 2021-08-18 Eliana Pastor , Luca de Alfaro , Elena Baralis

In this paper, we focus on exploiting the group structure for large-dimensional factor models, which captures the homogeneous effects of common factors on individuals within the same group. In view of the fact that datasets in…

Methodology · Statistics 2024-05-14 Yong He , Xiaoyang Ma , Xingheng Wang , Yalin Wang

We study the problem of training machine learning models incrementally with batches of samples annotated with noisy oracles. We select each batch of samples that are important and also diverse via clustering and importance sampling. More…

Machine Learning · Computer Science 2020-10-30 Gaurav Gupta , Anit Kumar Sahu , Wan-Yi Lin

The randomized controlled trial (RCT) is the gold standard for estimating the average treatment effect (ATE) of a medical intervention but requires 100s-1000s of subjects, making it expensive and difficult to implement. While a cross-over…

Signal Processing · Electrical Eng. & Systems 2023-05-10 Sayeri Lala , Niraj K. Jha

Clinical trials are critical for advancing medical treatments but remain prohibitively expensive and time-consuming. Accurate prediction of clinical trial outcomes can significantly reduce research and development costs and accelerate drug…

Machine Learning · Computer Science 2025-06-06 Fengze Liu , Haoyu Wang , Joonhyuk Cho , Dan Roth , Andrew W. Lo

Sample selection is a prevalent method in learning with noisy labels, where small-loss data are typically considered as correctly labeled data. However, this method may not effectively identify clean hard examples with large losses, which…

Machine Learning · Computer Science 2023-08-29 Suqin Yuan , Lei Feng , Tongliang Liu

Supervised learning algorithms are heavily reliant on annotated datasets to train machine learning models. However, the curation of the annotated datasets is laborious and time consuming due to the manual effort involved and has become a…

Computation and Language · Computer Science 2022-09-27 Ramya Tekumalla , Juan M. Banda

Covariate adjustment is widely recommended to improve statistical efficiency in randomized clinical trials (RCTs), yet empirical evidence comparing available strategies remains limited. This lack of real-world evaluation leaves unresolved…

Applications · Statistics 2026-02-03 Yulin Shao , Liangbo Lyu , Menggang Yu , Bingkai Wang