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Randomized experiments are the gold standard for estimating the average treatment effect (ATE). While covariate adjustment can reduce the asymptotic variances of the unbiased Horvitz-Thompson estimators for the ATE, it suffers from…

Methodology · Statistics 2025-08-22 Xin Lu , Lei Shi , Hanzhong Liu , Peng Ding

While deep learning holds great promise for disease diagnosis and prognosis in cardiac magnetic resonance imaging, its progress is often constrained by highly imbalanced and biased training datasets. To address this issue, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Grzegorz Skorupko , Richard Osuala , Zuzanna Szafranowska , Kaisar Kushibar , Vien Ngoc Dang , Nay Aung , Steffen E Petersen , Karim Lekadir , Polyxeni Gkontra

When testing for the mean vector in a high dimensional setting, it is generally assumed that the observations are independently and identically distributed. However if the data are dependent, the existing test procedures fail to preserve…

Statistics Theory · Mathematics 2014-11-17 Deepak Nag Ayyala , Junyong Park , Anindya Roy

In applied research, it is often sensible to account for one or several covariates when testing for differences between multivariate means of several groups. However, the "classical" parametric multivariate analysis of covariance (MANCOVA)…

Methodology · Statistics 2020-04-28 Georg Zimmermann , Markus Pauly , Arne C. Bathke

Given a pair of non-negative random variables $X$ and $Y$, we introduce a class of nonparametric tests for the null hypothesis that $X$ dominates $Y$ in the total time on test order. Critical values are determined using bootstrap-based…

Statistics Theory · Mathematics 2025-06-25 Tommaso Lando , Sirio Legramanti

Measurement non-invariance arises when the psychometric properties of a scale differ across subgroups, undermining the validity of group comparisons. At the item level, such non-invariance manifests as differential item functioning (DIF),…

Methodology · Statistics 2026-01-27 Gabriel Wallin , Qi Huang

In this work, we propose MixMOOD - a systematic approach to mitigate effect of class distribution mismatch in semi-supervised deep learning (SSDL) with MixMatch. This work is divided into two components: (i) an extensive out of distribution…

Discrete but ordered covariates are quite common in applied statistics, and some regularized fitting procedures have been proposed for proper handling of ordinal predictors in statistical modeling. In this study, we show how quadratic…

Methodology · Statistics 2022-04-25 Jan Gertheiss , Fabian Scheipl , Tina Lauer , Harald Ehrhardt

Heteroskedasticity poses several methodological challenges in designing valid and powerful procedures for simultaneous testing of composite null hypotheses. In particular, the conventional practice of standardizing or re-scaling…

Methodology · Statistics 2025-09-04 Bowen Gang , Trambak Banerjee

Valid statistical inference is challenging when the sample is subject to unknown selection bias. Data integration can be used to correct for selection bias when we have a parallel probability sample from the same population with some common…

Methodology · Statistics 2023-07-24 Zhonglei Wang , Shu Yang , Jae Kwang Kim

4D medical image interpolation is essential for improving temporal resolution and diagnostic precision in clinical applications. Previous works ignore the problem of distribution shifts, resulting in poor generalization under different…

Image and Video Processing · Electrical Eng. & Systems 2025-02-05 Qikang Zhang , Yingjie Lei , Zihao Zheng , Ziyang Chen , Zhonghao Xie

Food authenticity studies are concerned with determining if food samples have been correctly labeled or not. Discriminant analysis methods are an integral part of the methodology for food authentication. Motivated by food authenticity…

Methodology · Statistics 2010-10-08 Thomas Brendan Murphy , Nema Dean , Adrian E. Raftery

Ordinal data is widely prevalent in clinical and other domains, yet there is a lack of both modern, machine-learning based methods and publicly available software to address it. In this paper, we present a model-agnostic method of ordinal…

Machine Learning · Computer Science 2026-03-19 Noam H. Rotenberg , Andreia V. Faria , Brian Caffo

Emerging evidence indicates that human cancers are intricately linked to human microbiomes, forming an inseparable connection. However, due to limited sample sizes and significant data loss during collection for various reasons, some…

Genomics · Quantitative Biology 2024-08-16 Xinyuan Shi , Fangfang Zhu , Wenwen Min

Many real-world classification problems are significantly class-imbalanced to detriment of the class of interest. The standard set of proper evaluation metrics is well-known but the usual assumption is that the test dataset imbalance equals…

Machine Learning · Computer Science 2020-04-16 Jan Brabec , Tomáš Komárek , Vojtěch Franc , Lukáš Machlica

In the problem of composite hypothesis testing, identifying the potential uniformly most powerful (UMP) unbiased test is of great interest. Beyond typical hypothesis settings with exponential family, it is usually challenging to prove the…

Methodology · Statistics 2022-08-03 Tianyu Zhan , Jian Kang

We consider a new group testing model wherein each item is a binary random variable defined by an a priori probability of being defective. We assume that each probability is small and that items are independent, but not necessarily…

Information Theory · Computer Science 2018-07-24 Tongxin Li , Chun Lam Chan , Wenhao Huang , Tarik Kaced , Sidharth Jaggi

In the big data era, integrating diverse data modalities poses significant challenges, particularly in complex fields like healthcare. This paper introduces a new process model for multimodal Data Fusion for Data Mining, integrating…

Artificial Intelligence · Computer Science 2024-06-04 David Restrepo , Chenwei Wu , Constanza Vásquez-Venegas , Luis Filipe Nakayama , Leo Anthony Celi , Diego M López

Meta-analyses of clinical trials targeting rare events face particular challenges when the data lack adequate numbers of events for all treatment arms. Especially when the number of studies is low, standard meta-analysis methods can lead to…

Applications · Statistics 2020-01-20 Burak Kürsad Günhan , Christian Röver , Tim Friede

This paper provides a general framework for testing instrument validity in heterogeneous causal effect models. The generalization includes the cases where the treatment can be multivalued ordered or unordered. Based on a series of testable…

Econometrics · Economics 2023-10-11 Zhenting Sun