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We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Image registration is a process of aligning two or more images of same objects using geometric transformation. Most of the existing approaches work on the assumption of location invariance. These approaches require object-centric images to…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Deepak Mishra , Rajeev Ranjan , Santanu Chaudhury , Mukul Sarkar , Arvinder Singh Soin

The ability to build maps is a key functionality for the majority of mobile robots. A central ingredient to most mapping systems is the registration or alignment of the recorded sensor data. In this paper, we present a general methodology…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Bartolomeo Della Corte , Igor Bogoslavskyi , Cyrill Stachniss , Giorgio Grisetti

The deformable registration of images of different modalities, essential in many medical imaging applications, remains challenging. The main challenge is developing a robust measure for image overlap despite the compared images capturing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Joel Honkamaa , Pekka Marttinen

We propose an adaptive training scheme for unsupervised medical image registration. Existing methods rely on image reconstruction as the primary supervision signal. However, nuisance variables (e.g. noise and covisibility), violation of the…

Image and Video Processing · Electrical Eng. & Systems 2024-07-19 Xiaoran Zhang , John C. Stendahl , Lawrence Staib , Albert J. Sinusas , Alex Wong , James S. Duncan

Medical multimodal representation learning aims to integrate heterogeneous data into unified patient representations to support clinical outcome prediction. However, real-world medical datasets commonly contain systematic biases from…

Machine Learning · Computer Science 2026-05-19 Xiaoguang Zhu , Linxiao Gong , Lianlong Sun , Yang Liu , Haoyu Wang , Jing Liu

Deformable image registration can obtain dynamic information about images, which is of great significance in medical image analysis. The unsupervised deep learning registration method can quickly achieve high registration accuracy without…

Computer Vision and Pattern Recognition · Computer Science 2022-07-19 Xiao Fan , Shuxin Zhuang , Zhemin Zhuang , Ye Yuan , Shunmin Qiu , Alex Noel Joseph Raj , Yibiao Rong

Imaging in clinical routine is subject to changing scanner protocols, hardware, or policies in a typically heterogeneous set of acquisition hardware. Accuracy and reliability of deep learning models suffer from those changes as data and…

Machine Learning · Computer Science 2021-06-08 Matthias Perkonigg , Johannes Hofmanninger , Georg Langs

In image-guided neurosurgery, current commercial systems usually provide only rigid registration, partly because it is harder to predict, validate and understand non-rigid registration error. For instance, when surgeons see a discrepancy in…

Computer Vision and Pattern Recognition · Computer Science 2020-03-24 Jie Luo , Sarah Frisken , Duo Wang , Alexandra Golby , Masashi Sugiyama , William M. Wells

Many classification techniques when the data are curves or functions have been recently proposed. However, the presence of misaligned problems in the curves can influence the performance of most of them. In this paper, we propose a…

Methodology · Statistics 2020-11-05 Lin Tang , Pengcheng Zeng , Jian Qing Shi , Won-Seok Kim

Registration is a fundamental task in medical robotics and is often a crucial step for many downstream tasks such as motion analysis, intra-operative tracking and image segmentation. Popular registration methods such as ANTs and NiftyReg…

Computer Vision and Pattern Recognition · Computer Science 2021-03-26 Wentao Zhu , Yufang Huang , Daguang Xu , Zhen Qian , Wei Fan , Xiaohui Xie

We present a meta-learning framework for interactive medical image registration. Our proposed framework comprises three components: a learning-based medical image registration algorithm, a form of user interaction that refines registration…

Image and Video Processing · Electrical Eng. & Systems 2022-10-28 Zachary M. C. Baum , Yipeng Hu , Dean Barratt

Medical image registration is critical for aligning anatomical structures across imaging modalities such as computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound. Among existing techniques, non-rigid registration (NRR)…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Sneha Sree C. , Dattesh Shanbhag , Sudhanya Chatterjee

In general, the problem of non-rigid registration is about matching two different scans of a dynamic object taken at two different points in time. These scans can undergo both rigid motions and non-rigid deformations. Since new parts of the…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Alireza Ahmadi

Learning non-rigid registration in an end-to-end manner is challenging due to the inherent high degrees of freedom and the lack of labeled training data. In this paper, we resolve these two challenges simultaneously. First, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2021-04-14 Wanquan Feng , Juyong Zhang , Hongrui Cai , Haofei Xu , Junhui Hou , Hujun Bao

Diffeomorphic deformable image registration is one of the crucial tasks in medical image analysis, which aims to find a unique transformation while preserving the topology and invertibility of the transformation. Deep convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2022-02-09 Ameneh Sheikhjafari , Michelle Noga , Kumaradevan Punithakumar , Nilanjan Ray

Medical image registration is vital for disease diagnosis and treatment with its ability to merge diverse information of images, which may be captured under different times, angles, or modalities. Although several surveys have reviewed the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Qiushi Nie , Xiaoqing Zhang , Yan Hu , Mingdao Gong , Jiang Liu

In human neuroimaging studies, atlas registration enables mapping MRI scans to a common coordinate frame, which is necessary to aggregate data from multiple subjects. Machine learning registration methods have achieved excellent speed and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-08 Karthik Gopinath , Xiaoling Hu , Malte Hoffmann , Oula Puonti , Juan Eugenio Iglesias

Purpose: Optical imaging is evolving as a key technique for advanced sensing in the operating room. Recent research has shown that machine learning algorithms can be used to address the inverse problem of converting pixel-wise multispectral…

Multi-contrast magnetic resonance (MR) image registration is useful in the clinic to achieve fast and accurate imaging-based disease diagnosis and treatment planning. Nevertheless, the efficiency and performance of the existing registration…

Image and Video Processing · Electrical Eng. & Systems 2021-02-17 Weijian Huang , Hao Yang , Xinfeng Liu , Cheng Li , Ian Zhang , Rongpin Wang , Hairong Zheng , Shanshan Wang