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Faced with the 2020 SARS-CoV2 epidemic, public health officials have been seeking models that could be used to predict not only the number of new cases but also the levels of hospitalisation, critical care and deaths. In this paper we…

Populations and Evolution · Quantitative Biology 2020-12-24 Jonathan Wells , Chris Robertson , Vincent Marmara , Alan Yeung , Adam Kleczkowski

This paper presents a detailed mathematical investigation into the dynamics of COVID-19 infections through extended Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological models. By…

Populations and Evolution · Quantitative Biology 2025-05-21 Caleb Traxler , Minh Ton , Nameer Ahmed , Sasha Prostota , Annie Cheng

To forecast the time dynamics of an epidemic, we propose a discrete stochastic model that unifies and generalizes previous approaches to the subject. Viewing a given population of individuals or groups of individuals with given health state…

While COVID-19 has resulted in a significant increase in global mortality rates, the impact of the pandemic on mortality from other causes remains uncertain. To gain insight into the broader effects of COVID-19 on various causes of death,…

Applications · Statistics 2024-09-05 Wei Zhang , Antonietta Mira , Ernst C. Wit

Tracking the spread of infectious disease during a pandemic has posed a great challenge to the governments and health sectors on a global scale. To facilitate informed public health decision-making, the concerned parties usually rely on…

Methodology · Statistics 2023-06-05 Tejasv Bedi , Yanxun Xu , Qiwei Li

In this paper we propose a novel SEIR stochastic epidemic model. A distinguishing feature of this new model is that it allows us to consider a set up under general latency and infectious period distributions. To some extent, queuing systems…

Quantitative Methods · Quantitative Biology 2023-06-29 Edilson F. Arruda , Rodrigo e Alvim Alexandre , Marcelo D. Fragoso , João B. R. do val , Sinnu S. Thomas

For many infectious disease outbreaks, the at-risk population changes their behavior in response to the outbreak severity, causing the transmission dynamics to change in real-time. Behavioral change is often ignored in epidemic modeling…

Methodology · Statistics 2023-10-25 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

In this paper we explore a time-depended SEIR model, in which the dynamics of the infection in four groups from a selected target group (population), divided according to the infection, are modeled by a system of nonlinear ordinary…

Populations and Evolution · Quantitative Biology 2021-03-31 Svetozar Margenov , Nedyu Popivanov , Iva Ugrinova , Stanislav Harizanov , Tsvetan Hristov

As COVID-19 spread through the United States in 2020, states began to set up alert systems to inform policy decisions and serve as risk communication tools for the general public. Many of these systems, like in Ohio, included indicators…

Applications · Statistics 2023-05-12 David Kline , Ayaz Hyder , Enhao Liu , Michael Rayo , Samuel Malloy , Elisabeth Root

We study Susceptible-Exposed-Asymptomatic-Infectious-Recovered (SEAIR) epidemic spreading model of COVID-19. It captures two important characteristics of the infectiousness of COVID-19: delayed start and its appearance before onset of…

Physics and Society · Physics 2021-02-03 Lasko Basnarkov

This paper proposes a data-driven approximate Bayesian computation framework for parameter estimation and uncertainty quantification of epidemic models, which incorporates two novelties: (i) the identification of the initial conditions by…

Applications · Statistics 2023-06-28 Americo Cunha , David A. W. Barton , Thiago G. Ritto

Phenomenological and deterministic models are often used for the estimation of transmission parameters in an epidemic and for the prediction of its growth trajectory. Such analyses are usually based on single peak outbreak dynamics. In…

Populations and Evolution · Quantitative Biology 2022-01-20 D. P. Mahapatra , S. Triambak

Individual-based models of contagious processes are useful for predicting epidemic trajectories and informing intervention strategies. In such models, the incorporation of contact network information can capture the non-randomness and…

Populations and Evolution · Quantitative Biology 2023-11-09 Maxwell H. Wang , Jukka-Pekka Onnela

In this short note we model the region-wise trends of the evolution to COVID-19 infections using a stochastic SIR model. The SIR dynamics are expressed using \textit{It\^o-stochastic differential equations}. We first derive the parameters…

Populations and Evolution · Quantitative Biology 2020-04-17 Ashutosh Simha , R. Venkatesha Prasad , Sujay Narayana

In this work, we develop a spatial SEIAR-type epidemic model considering a quarantined population (denoted as Q), which we call the SQEIAR model. The dynamics of the SQEIAR model are described by six Partial Differential Equations (PDEs)…

Dynamical Systems · Mathematics 2025-01-27 Elghandouri Mohammed , Ezzinbi Khalil , Youness Mezzan

This paper is concerned with nonlinear modeling and analysis of the COVID-19 pandemic currently ravaging the planet. There are two objectives: to arrive at an appropriate model that captures the collected data faithfully, and to use that as…

Populations and Evolution · Quantitative Biology 2020-10-15 C. A. K. Kwuimy , Foad Nazari , Xun Jiao , Pejman Rohani , C. Nataraj

The COVID-19 pandemic provided many modeling challenges to investigate the evolution of an epidemic process over areal units. A suitable encompassing model must describe the spatio-temporal variations of the disease infection rate of…

Methodology · Statistics 2023-11-20 Pierfrancesco Alaimo Di Loro , Dankmar Boehning , Sujit Sahu

We consider the SEIRS epidemiology model with such features of the COVID-19 outbreak as: abundance of unidentified infected individuals, limited time of immunity and a possibility of vaccination. The control of the pandemic dynamics is…

Populations and Evolution · Quantitative Biology 2026-03-31 J. Ilnytskyi , T. Patsahan

The novel coronavirus disease (COVID-19) is a public health problem once according to the World Health Organization up to June 10th, 2020, more than 7.1 million people were infected, and more than 400 thousand have died worldwide. In the…

Populations and Evolution · Quantitative Biology 2020-07-22 Ramon Gomes da Silva , Matheus Henrique Dal Molin Ribeiro , Viviana Cocco Mariani , Leandro dos Santos Coelho

This work constructs, analyzes, and simulates a new compartmental SEIR-type model for the dynamics and potential control of the current COVID-19 pandemic. The novelty in this work is two-fold. First, the population is divided according to…

Populations and Evolution · Quantitative Biology 2021-05-14 Aycil Cesmelioglu , Kenneth L. Kuttler , Meir Shillor , Anna M. Spagnuolo