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In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

Populations and Evolution · Quantitative Biology 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

The long duration of the COVID-19 pandemic allowed for multiple bursts in the infection and death rates, the so-called epidemic waves. This complex behavior is no longer tractable by simple compartmental model and requires more…

We propose a robust parameter estimation method for dynamical systems based on Statistical Learning techniques which aims to estimate a set of parameters that well fit the dynamics in order to obtain robust evidences about the qualitative…

Methodology · Statistics 2021-02-26 Diego Marcondes

Epidemic models play a key role in understanding and responding to the emerging COVID-19 pandemic. Widely used compartmental models are static and are of limited use to evaluate intervention strategies with the emerging pandemic. Applying…

Populations and Evolution · Quantitative Biology 2021-01-01 Shuo Wang , Xian Yang , Ling Li , Philip Nadler , Rossella Arcucci , Yuan Huang , Zhongzhao Teng , Yike Guo

In this paper, we propose a new real-time differential virus transmission model, which can give more accurate and robust short-term predictions of COVID-19 transmitted infectious disease with benefits of near-term trend projection.…

Populations and Evolution · Quantitative Biology 2020-05-05 Sheldon X. D. Tan , Liang Chen

We demonstrate the ability of statistical data assimilation to identify the measurements required for accurate state and parameter estimation in an epidemiological model for the novel coronavirus disease COVID-19. Our context is an effort…

Populations and Evolution · Quantitative Biology 2020-08-04 Eve Armstrong , Manuela Runge , Jaline Gerardin

The evolution of epidemiological parameters, such as instantaneous reproduction number Rt, is important for understanding the transmission dynamics of infectious diseases. Current estimates of time-varying epidemiological parameters often…

Applications · Statistics 2021-10-26 Xian Yang , Shuo Wang , Yuting Xing , Ling Li , Richard Yi Da Xu , Karl J. Friston , Yike Guo

The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

Applications · Statistics 2022-04-11 Joshua P. Keller , Tianjian Zhou , Andee Kaplan , G. Brooke Anderson , Wen Zhou

We introduce a minimalist outbreak forecasting model that combines data-driven parameter estimation with variational data assimilation. By focusing on the fundamental components of nonlinear disease transmission and representing data in a…

Populations and Evolution · Quantitative Biology 2021-10-12 Hannah R. Biegel , Joceline Lega

Severe acute respiratory disease SARS-CoV-2 has had a found impact on public health systems and healthcare emergency response especially with respect to making decisions on the most effective measures to be taken at any given time. As…

Machine Learning · Computer Science 2023-09-19 Charithea Stylianides , Kleanthis Malialis , Panayiotis Kolios

The acute phase of the Covid-19 pandemic has made apparent the need for decision support based upon accurate epidemic modeling. This process is substantially hampered by under-reporting of cases and related data incompleteness issues. In…

Applications · Statistics 2026-03-10 Anastasios Apsemidis , Nikolaos Demiris

A study of changes in the transmission of a disease, in particular, a new disease like COVID-19, requires very flexible models which can capture, among others, the effects of non-pharmacological and pharmacological measures, changes in…

Epidemiological models contain a set of parameters that must be adjusted based on available observations. Once a model has been calibrated, it can be used as a forecasting tool to make predictions and to evaluate contingency plans. It is…

We present a data-driven optimal control approach which integrates the reported partial data with the epidemic dynamics for COVID-19. We use a basic Susceptible-Exposed-Infectious-Recovered (SEIR) model, the model parameters are…

Optimization and Control · Mathematics 2020-12-22 Hailiang Liu , Xuping Tian

We propose a deterministic SAIVRD model and a stochastic SARV model of the epidemic COVID-19 involving asymptomatic infections and vaccinations to conduct data forecasts using time-dependent parameters. The forecast by our deterministic…

Populations and Evolution · Quantitative Biology 2022-09-28 Bo-Sheng Chen , Zong-Ying Wu , Yen-Jia Chen , Jann-Long Chern

This technical report describes a dynamic causal model of the spread of coronavirus through a population. The model is based upon ensemble or population dynamics that generate outcomes, like new cases and deaths over time. The purpose of…

Stochastic epidemic models which incorporate interactions between space and human mobility are a key tool to inform prioritisation of outbreak control to appropriate locations. However, methods for fitting such models to national-level…

We consider a flexible Bayesian evidence synthesis approach to model the age-specific transmission dynamics of COVID-19 based on daily mortality counts. The temporal evolution of transmission rates in populations containing multiple types…

In an effort to provide regional decision support for the public healthcare, we design a data-driven compartment-based model of COVID-19 in Sweden. From national hospital statistics we derive parameter priors, and we develop linear…

Applications · Statistics 2023-07-31 Robin Marin , Håkan Runvik , Alexander Medvedev , Stefan Engblom
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