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A key challenge in environmental health research is unmeasured spatial confounding, driven by unobserved spatially structured variables that influence both treatment and outcome. A common approach is to fit a spatial regression that models…

Methodology · Statistics 2025-12-23 Sophie M. Woodward , Francesca Dominici , Jose R. Zubizarreta

Unmeasured confounding is a major challenge for identifying causal relationships from non-experimental data. Here, we propose a method that can accommodate unmeasured discrete confounding. Extending recent identifiability results in deep…

Machine Learning · Computer Science 2024-08-13 Patrick Burauel , Frederick Eberhardt , Michel Besserve

Various methods have recently been proposed to estimate causal effects with confidence intervals that are uniformly valid over a set of data generating processes when high-dimensional nuisance models are estimated by post-model-selection or…

Methodology · Statistics 2025-10-07 Niloofar Moosavi , Tetiana Gorbach , Xavier de Luna

Residuals in regression models are often spatially correlated. Prominent examples include studies in environmental epidemiology to understand the chronic health effects of pollutants. I consider the effects of residual spatial structure on…

Methodology · Statistics 2010-11-05 Christopher J. Paciorek

Semi-structured regression models enable the joint modeling of interpretable structured and complex unstructured feature effects. The structured model part is inspired by statistical models and can be used to infer the input-output…

Machine Learning · Computer Science 2024-01-24 Daniel Dold , David Rügamer , Beate Sick , Oliver Dürr

In this article, we construct empirical likelihood (EL)-weighted estimators of linear functionals of a probability measure in the presence of side information. Motivated by nuisance parameters in semiparametric models with possibly infinite…

Statistics Theory · Mathematics 2023-01-25 Shan Wang , Hanxiang Peng

Causal graphs may inform covariate adjustment for estimating causal effects and improve estimation efficiency by exploiting the graphical structure. In many applications, however, the target causal parameter may not be point-identified due…

Weighting methods are popular tools for estimating causal effects; assessing their robustness under unobserved confounding is important in practice. In the following paper, we introduce a new set of sensitivity models called "variance-based…

Methodology · Statistics 2023-03-14 Melody Huang , Samuel D. Pimentel

We explore methods to reduce the impact of unobserved confounders on the causal mediation analysis of high-dimensional mediators with spatially smooth structures, such as brain imaging data. The key approach is to incorporate the latent…

Methodology · Statistics 2026-05-29 Yuliang Xu , Shu Yang , Jian Kang

Inferring causal relationships or related associations from observational data can be invalidated by the existence of hidden confounding. We focus on a high-dimensional linear regression setting, where the measured covariates are affected…

Methodology · Statistics 2021-07-22 Zijian Guo , Domagoj Ćevid , Peter Bühlmann

Inferring the causal effect of a treatment on an outcome in an observational study requires adjusting for observed baseline confounders to avoid bias. However, adjusting for all observed baseline covariates, when only a subset are…

Methodology · Statistics 2021-02-04 Wen Wei Loh , Stijn Vansteelandt

Coarsened exact matching (CEM) is often promoted as a superior alternative to propensity score matching (PSM) for addressing imbalance, model dependence, bias, and efficiency. However, this recommendation remains uncertain. First, CEM is…

Methodology · Statistics 2026-02-03 Fei Wan

Unobserved confounders are a long-standing issue in causal inference using propensity score methods. This study proposed nonparametric indices to quantify the impact of unobserved confounders through pseudo-experiments with an application…

Methodology · Statistics 2020-08-27 Beilin Jia , Donglin Zeng , Qing Yang , Wei Pan

Structural equation models (SEMs) are commonly used to study the structural relationship between observed variables and latent constructs. Recently, Bayesian fitting procedures for SEMs have received more attention thanks to their potential…

Methodology · Statistics 2024-07-12 Khue-Dung Dang , Luca Maestrini , Francis K. C. Hui

Identification of treatment effects in the presence of unmeasured confounding is a persistent problem in the social, biological, and medical sciences. The problem of unmeasured confounding in settings with multiple treatments is most common…

Methodology · Statistics 2022-07-12 Wang Miao , Wenjie Hu , Elizabeth L. Ogburn , Xiaohua Zhou

Sensitivity analysis is popular in dealing with missing data problems particularly for non-ignorable missingness. It analyses how sensitively the conclusions may depend on assumptions about missing data e.g. missing data mechanism (MDM). We…

Methodology · Statistics 2015-01-26 Peng Yin , Jian Qing Shi

Establishing cause-effect relationships from observational data often relies on untestable assumptions. It is crucial to know whether, and to what extent, the conclusions drawn from non-experimental studies are robust to potential…

Finite-sample bias is a pervasive challenge in the estimation of structural equation models (SEMs), especially when sample sizes are small or measurement reliability is low. A range of methods have been proposed to improve finite-sample…

Methodology · Statistics 2026-03-30 Haziq Jamil , Yves Rosseel , Oliver Kemp , Ioannis Kosmidis

Recent theoretical work in causal inference has explored an important class of variables which, when conditioned on, may further amplify existing unmeasured confounding bias (bias amplification). Despite this theoretical work, existing…

Methodology · Statistics 2020-03-20 Tyrel Stokes , Russell Steele , Ian Shrier

Despite their popularity, machine learning predictions are sensitive to potential unobserved predictors. This paper proposes a general algorithm that assesses how the omission of an unobserved variable with high explanatory power could…

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