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The blood-brain barrier (BBB) serves as a protective barrier that separates the brain from the circulatory system, regulating the passage of substances into the central nervous system. Assessing the BBB permeability of potential drugs is…

Quantitative Methods · Quantitative Biology 2024-09-10 Shivesh Prakash

The introduction of computational techniques to analyze chemical data has given rise to the analytical study of biological systems, known as "bioinformatics". One facet of bioinformatics is using machine learning (ML) technology to detect…

Quantitative Methods · Quantitative Biology 2022-08-23 Tanish Jain , Praveen Kumar Pandian Shanmuganathan

Novel approaches for predicting the outcomes of blood-brain barrier (BBB) opening with focused ultrasound (FUS) and microbubbles are highly desired. This study aims to explore machine learning-based methods for reliably predicting the…

Medical Physics · Physics 2023-06-08 Wenjing Li , Chenchen Bing , Haixin Dai , Rajiv Chopra , Qian Wang , Bingbing Cheng

Predicting whether a molecule can cross the blood-brain barrier (BBB) is a key step in early-stage neuro-pharmaceutical design, directly influencing the efficiency and success rate of drug development. Traditional methods based on…

Quantitative Methods · Quantitative Biology 2026-03-16 Zihan Yang , Yuchen Xiao

Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…

Brain-machine interfaces (BMIs), particularly those based on electroencephalography (EEG), offer promising solutions for assisting individuals with motor disabilities. However, challenges in reliably interpreting EEG signals for specific…

Signal Processing · Electrical Eng. & Systems 2025-04-23 Biplov Paneru , Bipul Thapa , Bishwash Paneru , Sanjog Chhetri Sapkota

The development of neurologically active drugs faces a challenge in treating brain diseases due to the blood-brain barrier's impermeability. High-intensity focused ultrasound can open the barrier in a targeted manner, expanding treatment…

Brain signals constitute the information that are processed by millions of brain neurons (nerve cells and brain cells). These brain signals can be recorded and analyzed using various of non-invasive techniques such as the…

Neurons and Cognition · Quantitative Biology 2022-01-13 Almabrok Essa , Hari Kotte

The auditory pathway is widely distributed throughout the brain, and is perhaps one of the most interesting networks in the context of neuroplasticity. Accurate mapping of neural activity in the entire pathway, preferably noninvasively, and…

Medical Physics · Physics 2019-03-21 Guilherme Blazquez Freches , Cristina Chavarrias , Noam Shemesh

Non-invasive brain-computer interfaces (BCIs) have the potential to enable intuitive control of prosthetic limbs for individuals with upper limb amputations. However, existing EEG-based control systems face challenges related to signal…

Human-Computer Interaction · Computer Science 2025-11-21 Abdul Basit , Maha Nawaz , Muhammad Shafique

This research aims to decode hand grasps from Electroencephalograms (EEGs) for dexterous neuroprosthetic development and Brain-Computer Interface (BCI) applications, especially for patients with motor disorders. Particularly, it focuses on…

Signal Processing · Electrical Eng. & Systems 2025-05-19 Ali Rabiee , Sima Ghafoori , Anna Cetera , Reza Abiri

Brain-robot interaction (BRI) empowers individuals to control (semi-)automated machines through their brain activity, either passively or actively. In the past decade, BRI systems have achieved remarkable success, predominantly harnessing…

The classification of harmful brain activities, such as seizures and periodic discharges, play a vital role in neurocritical care, enabling timely diagnosis and intervention. Electroencephalography (EEG) provides a non-invasive method for…

Machine Learning · Computer Science 2025-10-21 Shivraj Singh Bhatti , Aryan Yadav , Mitali Monga , Neeraj Kumar

This research presents a novel method for noninvasive arterial blood pressure ABP prediction using speech signals employing a BERT based regression model Arterial blood pressure is a vital indicator of cardiovascular health and accurate…

Machine Learning · Computer Science 2025-09-25 Kainat

With the increasing popularity of telehealth, it becomes critical to ensure that basic physiological signals can be monitored accurately at home, with minimal patient overhead. In this paper, we propose a contactless approach for monitoring…

Machine Learning · Computer Science 2022-12-08 Hao He , Yuan Yuan , Ying-Cong Chen , Peng Cao , Dina Katabi

Brain biometrics based on electroencephalography (EEG) have been used increasingly for personal identification. Traditional machine learning techniques as well as modern day deep learning methods have been applied with promising results. In…

Electroencephalography (EEG) is a critical, non-invasive method to monitor electrical brain activity. EEGs can span anywhere from a couple seconds to multiple hours, posing a major hurdle for existing deep learning methods due to two major…

Artificial Intelligence · Computer Science 2026-05-28 Abhilash Durgam , Nyle Siddiqui , Jeffrey A. Chan-Santiago , Qiushi Fu , Elakkat D. Gireesh , Mubarak Shah

Objective. This study conduct an extensive Brain-computer interfaces (BCI) reproducibility analysis on open electroencephalography datasets, aiming to assess existing solutions and establish open and reproducible benchmarks for effective…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Sylvain Chevallier , Igor Carrara , Bruno Aristimunha , Pierre Guetschel , Sara Sedlar , Bruna Lopes , Sebastien Velut , Salim Khazem , Thomas Moreau

Electroencephalography (EEG) monitors ---by either intrusive or noninvasive electrodes--- time and frequency variations and spectral content of voltage fluctuations or waves, known as brain rhythms, which in some way uncover activity during…

Neurons and Cognition · Quantitative Biology 2019-03-13 Javier A. Galadí , Joaquín J. Torres , J. Marro

Action, cognition, emotion and perception can be mapped in the brain by using set of techniques. Translating unimodal concepts from one modality to another is an important step towards understanding the neural mechanisms. This paper…

Other Computer Science · Computer Science 2012-12-18 Revati Shriram , Dr. M. Sundhararajan , Nivedita Daimiwal
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