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Low-intensity ultrasonic waves can remotely and nondestructively excite central nervous system (CNS) neurons. While diverse applications for this effect are already emerging, the biophysical transduction mechanism underlying this excitation…

Neurons and Cognition · Quantitative Biology 2014-01-29 Michael Plaksin , Shy Shoham , Eitan Kimmel

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

Machine Learning · Computer Science 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

We proposed a novel visual stimulus for brain-computer interface. The stimulus is in the form gaiting sequence of a human. The hypothesis is that observing such a visual stimulus would simultaneously induce 1) steady-state motion visual…

Signal Processing · Electrical Eng. & Systems 2021-03-11 Xin Zhang , Guanghua Xu , Aravind Ravi , Sarah Pearce , Ning Jiang

Theories for visually guided action account for online control in the presence of reliable sources of visual information, and predictive control to compensate for visuomotor delay and temporary occlusion. In this study, we characterize the…

Other Computer Science · Computer Science 2018-05-17 Kamran Binaee , Anna Starynska , Jeff B Pelz , Christopher Kanan , Gabriel Jacob Diaz

Thalamic circuits are able to generate state-dependent oscillations of different frequencies and degrees of synchronization. However, only little is known how synchronous oscillations, like spindle oscillations in the thalamus, are…

Neurons and Cognition · Quantitative Biology 2010-03-11 Jörg Mayer , Heinz Georg Schuster , Jens Christian Claussen , Matthias Mölle

We employ a number of statistical measures to characterize neural discharge activity in cat retinal ganglion cells (RGCs) and in their target lateral geniculate nucleus (LGN) neurons under various stimulus conditions, and we develop a new…

Biological Physics · Physics 2007-05-23 Steven B. Lowen , Tsuyoshi Ozaki , Ehud Kaplan , Bahaa E. A. Saleh , Malvin C. Teich

Rhythms in electrical activity in the membrane of cells in the suprachiasmatic nucleus (SCN) are crucial for the function of the circadian timing system, which is characterized by the expression of the so-called clock genes. Intracellular…

Biological Physics · Physics 2015-03-23 J. M. Casado , M. Morillo

Neuromorphic networks can be described in terms of coarse-grained variables, where emergent sustained behaviours spontaneously arise if stochasticity is properly taken in account. For example it has been recently found that a directed…

Adaptation and Self-Organizing Systems · Physics 2020-01-23 Ilenia Apicella , Daniel Maria Busiello , Silvia Scarpetta , Samir Suweis

Non-invasive functional imaging of molecular and cellular processes of vision is expected to have immense impact on research and clinical diagnostics. Although suitable intrinsic optical signals (IOS) have been observed ex vivo and in…

Medical Physics · Physics 2017-02-08 Dierck Hillmann , Hendrik Spahr , Clara Pfäffle , Helge Sudkamp , Gesa Franke , Gereon Hüttmann

Optical simulators for the Ising model have demonstrated great promise for solving challenging problems in physics and beyond. Here, we develop a spatial optical simulator for a variety of classical statistical systems, including the clock,…

Optics · Physics 2024-12-19 Song-Tao Yu , Ming-Gen He , Sheng Fang , Youjin Deng , Zhen-Sheng Yuan

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

While traditional feed-forward filter models can reproduce the rate responses of retinal ganglion neurons to simple stimuli, they cannot explain why synchrony between spikes is much higher than expected by Poisson firing [6], and can be…

Neurons and Cognition · Quantitative Biology 2020-05-07 Christopher Warner , Friedrich T. Sommer

Neural systems can be modeled as networks of functionally connected neural elements. The resulting network can be analyzed using mathematical tools from network science and graph theory to quantify the system's topological organization and…

Neurons and Cognition · Quantitative Biology 2020-07-01 Richard F. Betzel , Katherine C. Wood , Christopher Angeloni , Maria Neimark Geffen , Danielle S. Bassett

The optical power spectrum is the prime observable to dissect, understand and design the long-time behavior of arrays of optically coupled semiconductor lasers. A long-standing issue has been identified within the literature on injection…

Optics · Physics 2024-03-01 Johanne Hizanidis , Vassilios Kovanis

Navigating through a physical environment to reach a desired location involves a complex interplay of cognitive, sensory, and motor functions. When navigating with others, experiencing a degree of behavioral and cognitive synchronization is…

Neurons and Cognition · Quantitative Biology 2024-06-11 Chun-Hsiang Chuang , Po-Hsun Peng , Yi-Chieh Chen

Precise control of neural activity -- modulating target neurons deep in the brain while leaving nearby neurons unaffected -- is an outstanding challenge in neuroscience, generally approached using invasive techniques. This study…

Neurons and Cognition · Quantitative Biology 2025-06-17 Guy Gaziv , Sarah Goulding , Ani Ayvazian-Hancock , Yoon Bai , James J. DiCarlo

There has become of increasing interest in transcranial alternating current stimulation (tACS) since its inception nearly a decade ago. tACS in modulating brain state is an active area of research and has been demonstrated effective in…

Neurons and Cognition · Quantitative Biology 2020-03-31 Bingchuan Liu , Xinyi Yan , Xiaogang Chen , Yijun Wang , Xiaorong Gao

We consider a model of basic inner retinal connectivity where bipolar and amacrine cells interconnect, and both cell types project onto ganglion cells, modulating their response output to the brain visual areas. We derive an analytical…

Neurons and Cognition · Quantitative Biology 2024-01-10 Evgenia Kartsaki , Gerrit Hilgen , Evelyne Sernagor , Bruno Cessac

Neurons in the visual cortex are correlated in their variability. The presence of correlation impacts cortical processing because noise cannot be averaged out over many neurons. In an effort to understand the functional purpose of…

Machine Learning · Computer Science 2018-04-04 Shamak Dutta , Bryan Tripp , Graham Taylor

The migration of cells is relevant for processes such as morphogenesis, wound healing, and invasion of cancer cells. In order to move, single cells deform cyclically. However, it is not understood how these shape oscillations influence…

Biological Physics · Physics 2019-09-04 Matteo Campo , Simon K. Schnyder , John J. Molina , Thomas Speck , Ryoichi Yamamoto
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