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The optimization of large experiments in fundamental science, such as detectors for subnuclear physics at particle colliders, shares with the optimization of complex systems for industrial or societal applications the common issue of…

Instrumentation and Detectors · Physics 2026-03-30 Tommaso Dorigo , Pietro Vischia , Shahzaib Abbas , Tosin Adewumi , Lama Alkhaled , Lorenzo Arsini , Muhammad Awais , Maxim Borisyak , András Bóta , Florian Bury , Sascha Caron , James Carzon , Long Chen , Prakash C. Chhipa , Paul Christakopoulos , Jacopo De Piccoli , Andrea De Vita , Zlatan Dimitrov , Michele Doro , Luigi Favaro , Francesco Ferranti , Santiago Folgueras , Rihab Gargouri , Nicolas R. Gauger , Andrea Giammanco , Christian Glaser , Tobias Golling , João A. Gonçalves , Hui Han , Hamza Hanif , Lukas Heinrich , Yan Chai Hum , Florent Imbert , Andreas Ipp , Michael Kagan , Noor Kainat Syeda , Rukshak Kapoor , Aparup Khatua , Eduard J. Kerkhoven , Jan Kieseler , Tobias Kortus , Ashish Kumar Singh , Marius S. Köppel , Daniel Lanchares , Ann Lee , Pelayo Leguina , Christos Leonidopoulos , Giuseppe Levi , Boying Li , Chang Liu , Marcus Liwicki , Karl Lowenmark , Enrico Lupi , Carlo Mancini-Terracciano , Dominik Maršík , Leonidas Matsakas , Hamam Mokayed , Federico Nardi , Amirhossein Nayebiastaneh , Xuan T. Nguyen , Aitor Orio , Jingjing Pan , Jigar Patel , Carmelo Pellegrino , María Pereira Martínez , Karolos Potamianos , Shah Rukh Qasim , Martin Ravn , Luis Recabarren Vergara , Humberto Reyes-González , Hipolito A. Riveros Guevara , Ippocratis D. Saltas , Rajkumar Saini , Fredrik Sandin , Alexander Schilling , Kylian Schmidt , Nicola Serra , Saqib Shahzad , Foteini Simistira Liwicki , Giles C. Strong , Kristian Tchiorniy , Mia Tosi , Andrey Ustyuzhanin , Xabier Cid Vidal , Kinga A. Wozniak , Mengqing Wu , Zahraa Zaher

Just like the scientific data they generate, simulation workflows for research should be findable, accessible, interoperable, and reusable (FAIR). However, while significant progress has been made towards FAIR data, the majority of science…

Digital Libraries · Computer Science 2022-05-04 Martin Hunt , Steven Clark , Daniel Mejia , Saaketh Desai , Alejandro Strachan

High-Level Synthesis (HLS) enables rapid prototyping of complex hardware designs by translating C or C++ code to low-level RTL code. However, the testing and evaluation of HLS designs still typically rely on slow RTL-level simulators that…

Performance · Computer Science 2024-04-18 Rishov Sarkar , Rachel Paul , Cong Hao

Quantum Machine Learning (QML) is an emerging field of research with potential applications to distributed collaborative learning, such as Split Learning (SL). SL allows resource-constrained clients to collaboratively train ML models with a…

Quantum Physics · Physics 2025-07-08 Hevish Cowlessur , Chandra Thapa , Tansu Alpcan , Seyit Camtepe

Pharmaceutical process design and development for generic, innovative, or personalized drugs have always been a time-consuming, costly, rigorous process, that involves multi-stage evaluation for better quality control and assurance. Large…

Emerging Technologies · Computer Science 2025-03-24 Leqi Lin , Xingyu Zhou , Kaiyuan Yang , Xizhong Chen

Scientific discovery is a closed-loop process in which hypotheses guide data acquisition and observations refine the hypothesis space. Yet most approaches reduce discovery to supervised learning over fixed datasets, where limited…

Machine Learning · Computer Science 2026-05-26 Sanchit Kabra , Nikhil Abhyankar , Saaketh Desai , Prasad Iyer , Chandan K Reddy

When considering different hardware platforms, not just the time-to-solution can be of importance but also the energy necessary to reach it. This is not only the case with battery powered and mobile devices but also with high-performance…

Performance · Computer Science 2020-06-30 Philip Heinisch , Katharina Ostaszewski , Hendrik Ranocha

High Level Synthesis (HLS) tools, like the Intel FPGA SDK for OpenCL, improve design productivity and enable efficient design space exploration guided by simple program directives (pragmas), but may sometimes miss important optimizations…

Hardware Architecture · Computer Science 2022-01-12 Adel Ejjeh , Vikram Adve , Rob Rutenbar

Hardware generation languages (HGLs) increase hardware design productivity by creating parameterized modules and test benches. Unfortunately, existing tools are not widely adopted due to several demerits, including limited support for…

Hardware Architecture · Computer Science 2023-09-12 Jintao Sun , Zeke Wang , Tao Lu , Wenzhi Chen

High-level synthesis (HLS) allows hardware designers to create hardware designs with high-level programming languages like C/C++/OpenCL, which greatly improves hardware design productivity. However, existing HLS flows require programmers'…

Hardware Architecture · Computer Science 2024-10-11 Haocheng Xu , Haotian Hu , Sitao Huang

Low-cost, high-throughput DNA and RNA sequencing (HTS) data is the backbone of the life sciences. Genome sequencing is now becoming a part of Predictive, Preventive, Personalized, and Participatory (termed 'P4') medicine. All genomic data…

Frugal Machine Learning (FML) refers to the practice of designing Machine Learning (ML) models that are efficient, cost-effective, and mindful of resource constraints. This field aims to achieve acceptable performance while minimizing the…

Machine Learning · Computer Science 2025-06-03 John Violos , Konstantina-Christina Diamanti , Ioannis Kompatsiaris , Symeon Papadopoulos

Automatic research with Large Language Models (LLMs) is rapidly gaining importance, driving the development of increasingly complex workflows involving multi-agent systems, planning, tool usage, code execution, and human-agent interaction…

Computation and Language · Computer Science 2025-10-09 Haofei Yu , Keyang Xuan , Fenghai Li , Kunlun Zhu , Zijie Lei , Jiaxun Zhang , Ziheng Qi , Kyle Richardson , Jiaxuan You

A common workflow in science and engineering is to (i) setup and deploy large experiments with tasks comprising an application and multiple parameter values; (ii) generate intermediate results; (iii) analyze them; and (iv) reprioritize the…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-11-10 Bruno Silva , Marco A. S. Netto , Renato L. F. Cunha

Power consumption is a major concern in data centers and HPC applications, with GPUs typically accounting for more than half of system power usage. While accurate power measurement tools are crucial for optimizing the energy efficiency of…

Current trends point to a future where large-scale scientific applications are tightly-coupled HPC/AI hybrids. Hence, we urgently need to invest in creating a seamless, scalable framework where HPC and AI/ML can efficiently work together…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-05-06 Jens Domke , Mohamed Wahib , Anshu Dubey , Tal Ben-Nun , Erik W. Draeger

In this work, we present a new approach to high level synthesis (HLS), where high level functions are first mapped to an architectural template, before hardware synthesis is performed. As FPGA platforms are especially suitable for…

Hardware Architecture · Computer Science 2016-06-22 Shaoyi Cheng , John Wawrzynek

This paper aims to efficiently enable Large Language Models (LLMs) to use multimodal tools. Advanced proprietary LLMs, such as ChatGPT and GPT-4, have shown great potential for tool usage through sophisticated prompt engineering.…

Computer Vision and Pattern Recognition · Computer Science 2023-05-31 Rui Yang , Lin Song , Yanwei Li , Sijie Zhao , Yixiao Ge , Xiu Li , Ying Shan

State-of-the-art Neural Network Architectures (NNAs) are challenging to design and implement efficiently in hardware. In the past couple of years, this has led to an explosion in research and development of automatic Neural Architecture…

Neural and Evolutionary Computing · Computer Science 2020-09-15 Philip Colangelo , Oren Segal , Alex Speicher , Martin Margala

Climate change is becoming one of the greatest challenges to the sustainable development of modern society. Renewable energies with low density greatly complicate the online optimization and control processes, where modern advanced…

Quantum Physics · Physics 2024-09-09 Junyu Liu , Han Zheng , Masanori Hanada , Kanav Setia , Dan Wu