Related papers: Beam delivery systems for linac-based proton thera…
Charged Particle Therapy is a technique for cancer treatment that exploits hadron beams, mostly protons and carbons. A critical issue is the monitoring of the dose released by the beam to the tumor and to the surrounding tissues. We present…
Synchrotron radiation has been used for many years as a beam diagnostic at electron accelerators. It is not normally associated with proton accelerators as the intensity of the radiation is too weak to make detection practical. However, if…
In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…
In recent years, intense efforts have been devoted to studying how nonlinear effects can be used to shape the transverse beam distribution by means of an adiabatic crossing of nonlinear resonances. By this approach, it is possible to split…
We propose the BayesDose-Framework, a Bayesian approach for fast and accurate dose prediction in proton therapy. Our framework is based on a previously published deterministic LSTM model and is trained and evaluated on simulated beamlet…
A new variant of the pencil-beam (PB) algorithm for dose distribution calculation for radiotherapy with protons and heavier ions, the grid-dose spreading (GDS) algorithm, is proposed. The GDS algorithm is intrinsically faster than…
For dose calculations in ion beam therapy, it is vital to accurately determine the relative stopping power (RSP) distribution within the treated volume. Currently, RSP values are extrapolated from Hounsfield units (HU), measured with x-ray…
Objective: Real-time adaptive proton range verification systems based on produced neutrons require accurate information on their non-isotropic momentum distributions within short times, for which Monte Carlo (MC) methods are too…
A dielectric-loaded linac powered by THz-pulses is one of the key parts of the "Attosecond X-ray Science: Imaging and Spectroscopy" (AXSIS) project at DESY, Hamburg. As in conventional accelerators, the AXSIS linac is designed to have phase…
The use of existing linacs, and in particular light source injectors, for free-electron laser (FEL) experiments is becoming more common due to the desire to test FELs at ever shorter wavelengths. The high-brightness, high-current beams…
Controlling non-linear effects in the transverse dynamics of charged particle beams in circular accelerators opens new possibilities for controlling some of the beam properties. Beam splitting by crossing a stable 1D non-linear resonance is…
High brightness electron accelerators, such as energy recovery linacs (ERL), often have complex particle distributions that can create difficulties in beam transport as well as matching to devices such as wigglers used to generate radiation…
The performance of the energy degrader in terms of beam properties directly impacts the design and cost of cyclotron-based proton therapy centers. The aim of this study is to evaluate the performances of different existing and novel…
In this work, we report on the advantageous aspects of the i-TED Compton imager for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that…
We propose an oAPT workflow that incorporates all these functionalities and validate its clinical implementation feasibility with prostate patients. AI-based auto-segmentation tool AccuContourTM (Manteia, Xiamen, China) was seamlessly…
We present a theoretical study of recent laser-alignment and mixed-field-orientation experiments of asymmetric top molecules. In these experiments, pendular states were created using linearly polarized strong ac electric fields from pulsed…
The pencil-beam model is valid only when elementary Gaussian beams are small enough with respect to lateral heterogeneity of a medium, which is not always the case in heavy charged particle radiotherapy. This work addresses a solution for…
In proton therapy, depth scanning of the irradiated object is performed by changing the Output Energy (OE) of the accelerated beam. In pulsed linear accelerators, adjustment of the OE is usually by changing the amplitude and/or phase of the…
We propose a method to transfer the population and control the state of two-level and three-level atoms speeding-up Adiabatic Passage techniques while keeping their robustness versus parameter variations. The method is based on…
Polar molecules, in strong-field seeking states, can be transported and focused by an alternating sequence of electric field gradients that focus in one transverse direction while defocusing in the other. We show, by calculation and…