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In drug discovery, it is vital to confirm the predictions of pharmaceutical properties from computational models using costly wet-lab experiments. Hence, obtaining reliable uncertainty estimates is crucial for prioritizing drug molecules…

Machine Learning · Computer Science 2023-10-19 Siddhartha Laghuvarapu , Zhen Lin , Jimeng Sun

This study presents an efficient incremental/decremental approach for big streams based on Kernel Ridge Regression (KRR), a frequently used data analysis in cloud centers. To avoid reanalyzing the whole dataset whenever sensors receive new…

Machine Learning · Computer Science 2017-11-10 Bo-Wei Chen , Nik Nailah Binti Abdullah , Sangoh Park

Click-Through Rate (CTR) prediction models are integral to a myriad of industrial settings, such as personalized search advertising. Current methods typically involve feature extraction from users' historical behavior sequences combined…

Machine Learning · Computer Science 2025-07-16 Lingwei Kong , Lu Wang , Changping Peng , Zhangang Lin , Ching Law , Jingping Shao

Quantifying the difference between two probability density functions, $p$ and $q$, using available data, is a fundamental problem in Statistics and Machine Learning. A usual approach for addressing this problem is the likelihood-ratio…

Machine Learning · Statistics 2023-11-06 Alejandro de la Concha , Nicolas Vayatis , Argyris Kalogeratos

Estimating density ratios has become increasingly important with the recent rise of score-based and diffusion-inspired methods. However, current tangent-based approaches rely on a high-variance learning objective, which leads to unstable…

Machine Learning · Statistics 2025-12-11 Wei Chen , Shigui Li , Jiacheng Li , Jian Xu , Zhiqi Lin , Junmei Yang , Delu Zeng , John Paisley , Qibin Zhao

In streaming scenarios, models must learn continuously, adapting to concept drifts without erasing previously acquired knowledge. However, existing research communities address these challenges in isolation. Continual Learning (CL) focuses…

Machine Learning · Computer Science 2025-12-15 Afonso Lourenço , João Gama , Eric P. Xing , Goreti Marreiros

Modern longitudinal data, for example from wearable devices, measures biological signals on a fixed set of participants at a diverging number of time points. Traditional statistical methods are not equipped to handle the computational…

Methodology · Statistics 2023-03-23 Lan Luo , Jingshen Wang , Emily C. Hector

Decentralized learning strategies allow a collection of agents to learn efficiently from local data sets without the need for central aggregation or orchestration. Current decentralized learning paradigms typically rely on an averaging…

Machine Learning · Computer Science 2025-01-24 Muyun Li , Aaron Fainman , Stefan Vlaski

Morden deep ensembles technique achieves strong uncertainty estimation performance by going through multiple forward passes with different models. This is at the price of a high storage space and a slow speed in the inference (test) time.…

Machine Learning · Computer Science 2024-03-13 Ha Manh Bui , Anqi Liu

Current evaluations of Continual Learning (CL) methods typically assume that there is no constraint on training time and computation. This is an unrealistic assumption for any real-world setting, which motivates us to propose: a practical…

We investigate the use of diffusion models as neural density estimators. The current approach to this problem involves converting the generative process to a smooth flow, known as the Probability Flow ODE. The log density at a given sample…

Machine Learning · Computer Science 2024-10-10 Akhil Premkumar

Most methods for estimating configurational entropy from molecular simulation data yield upper limits except for harmonic systems where they are exact. Problems arise at diffusive systems and the presence of conformational transitions.…

Chemical Physics · Physics 2019-10-22 Jürgen Schlitter , Matthias Massarczyk

Generative retrieval (GR) directly predicts the identifiers of relevant documents (i.e., docids) based on a parametric model. It has achieved solid performance on many ad-hoc retrieval tasks. So far, these tasks have assumed a static…

Information Retrieval · Computer Science 2025-09-30 Jiangui Chen , Ruqing Zhang , Jiafeng Guo , Maarten de Rijke , Wei Chen , Yixing Fan , Xueqi Cheng

Temporally consistent depth estimation is crucial for online applications such as augmented reality. While stereo depth estimation has received substantial attention as a promising way to generate 3D information, there is relatively little…

Computer Vision and Pattern Recognition · Computer Science 2022-12-12 Zhaoshuo Li , Wei Ye , Dilin Wang , Francis X. Creighton , Russell H. Taylor , Ganesh Venkatesh , Mathias Unberath

In recent years, online distillation has emerged as a powerful technique for adapting real-time deep neural networks on the fly using a slow, but accurate teacher model. However, a major challenge in online distillation is catastrophic…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Joachim Houyon , Anthony Cioppa , Yasir Ghunaim , Motasem Alfarra , Anaïs Halin , Maxim Henry , Bernard Ghanem , Marc Van Droogenbroeck

Calibrated estimates of uncertainty are critical for many real-world computer vision applications of deep learning. While there are several widely-used uncertainty estimation methods, dropout inference stands out for its simplicity and…

Computer Vision and Pattern Recognition · Computer Science 2020-11-09 Yichen Shen , Zhilu Zhang , Mert R. Sabuncu , Lin Sun

Humans and animals can learn complex predictive models that allow them to accurately and reliably reason about real-world phenomena, and they can adapt such models extremely quickly in the face of unexpected changes. Deep neural network…

Machine Learning · Computer Science 2019-01-30 Anusha Nagabandi , Chelsea Finn , Sergey Levine

Recurrent neural networks (RNNs) have brought a lot of advancements in sequence labeling tasks and sequence data. However, their effectiveness is limited when the observations in the sequence are irregularly sampled, where the observations…

Machine Learning · Computer Science 2022-12-29 Srinivas Anumasa , Geetakrishnasai Gunapati , P. K. Srijith

Online continual learning (online CL) studies the problem of learning sequential tasks from an online data stream without task boundaries, aiming to adapt to new data while alleviating catastrophic forgetting on the past tasks. This paper…

Machine Learning · Computer Science 2022-07-28 Zhen Wang , Liu Liu , Yajing Kong , Jiaxian Guo , Dacheng Tao

Estimating local false discovery rates (fdr) is central to large-scale multiple hypothesis testing, yet different methods often produce divergent results, and there is little guidance for selecting among them. Because ground truth…

Methodology · Statistics 2025-09-17 Jenna M. Landy , Giovanni Parmigiani
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