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Diffusion in an evolving environment is studied by continuos-time Monte Carlo simulations. Diffusion is modelled by continuos-time random walkers on a lattice, in a dynamic environment provided by bubbles between two one-dimensional…

Soft Condensed Matter · Physics 2010-11-22 Janne Juntunen , Juha Merikoski

We study a model for a protein searching for a target, using facilitated diffusion, on a DNA molecule confined in a finite volume. The model includes three distinct pathways for facilitated diffusion: (a) sliding - in which the protein…

Subcellular Processes · Quantitative Biology 2009-01-28 Michael Sheinman , Yariv Kafri

We seek to characterize the motility of mouse fibroblasts on 2D substrates. Utilizing automated tracking techniques, we find that cell trajectories are super-diffusive, where displacements scale faster than t^(1/2) in all directions. Two…

Soft Condensed Matter · Physics 2017-12-15 G Passucci , ME Brasch , JH Henderson , V Zaburdaev , ML Manning

Trajectories of endosomes inside living eukaryotic cells are highly heterogeneous in space and time and diffuse anomalously due to a combination of viscoelasticity, caging, aggregation and active transport. Some of the trajectories display…

Subcellular Processes · Quantitative Biology 2021-07-28 Nickolay Korabel , Daniel Han , Alessandro Taloni , Gianni Pagnini , Sergei Fedotov , Viki Allan , Thomas A. Waigh

The dynamics of diffusion in complex networks are widely studied to understand how entities, such as information, diseases, or behaviors, spread in an interconnected environment. Complex networks often present community structure, and tools…

Physics and Society · Physics 2025-12-09 Alina Dubovskaya , Caroline B. Pena , David J. P. O'Sullivan

We study diffusion of information packets on several classes of structured networks. Packets diffuse from a randomly chosen node to a specified destination in the network. As local transport rules we consider random diffusion and an…

Statistical Mechanics · Physics 2015-06-24 Bosiljka Tadic , Stefan Thurner

Many random growth models have the property that the set of discovered sites, scaled properly, converges to some deterministic set as time grows. Such results are known as shape theorems. Typically, not much is known about the shapes. For…

Machine Learning · Statistics 2020-06-26 Sebastian Rosengren

We develop new uncertainty propagation methods for feed-forward neural network architectures with leaky ReLU activation functions subject to random perturbations in the input vectors. In particular, we derive analytical expressions for the…

Machine Learning · Computer Science 2025-08-12 Jeremy Diamzon , Daniele Venturi

Aggregation and fragmentation of single molecules in the cell environment lead to a spectrum of diffusivities and to statistical laws of movement very different from typical Brownian motion. Current models of intracellular transport do not…

Statistical Mechanics · Physics 2020-07-08 M. Hidalgo-Soria , E. Barkai

Fluorescence microscopy has led to impressive quantitative models and new insights gained from richer sets of biomedical imagery. However, there is a dearth of rigorous and established bioimaging strategies for modeling spatiotemporal…

Subcellular Processes · Quantitative Biology 2019-05-01 Andrew Durden

Intracellular transport of organelles is fundamental to cell function and health. The mounting evidence suggests that this transport is in fact anomalous. However, the reasons for the anomaly is still under debate. We examined experimental…

Subcellular Processes · Quantitative Biology 2018-12-10 Nickolay Korabel , Thomas A. Waigh , Sergei Fedotov , Viki J. Allan

We consider the diffusion-advection problem in two simple cellular flow models (often invoked as examples for subdiffusive tracer's motion) and concentrate on the intermediate time range, in which the tracer's motion indeed may show…

Fluid Dynamics · Physics 2016-09-28 Patrick Pöschke , Igor M. Sokolov , Alexander A. Nepomnyashchy , Michael A. Zaks

Monte Carlo (MC) simulations of transport in random porous networks indicate that for high variances of the log-normal permeability distribution, the transport of a passive tracer is non-Fickian. Here we model this non-Fickian dispersion in…

Computational Physics · Physics 2018-08-01 Amir H. Delgoshaie , Patrick Jenny , Hamdi A. Tchelepi

Propagation of energetic particles across the mean field direction in turbulent magnetic fields is often described as spatial diffusion. Recently, it has been suggested that initially the particles propagate systematically along meandering…

Space Physics · Physics 2017-06-22 T. Laitinen , S. Dalla , D. Marriott

In order to characterize the mechanisms governing the diffusion of particles in biological scenarios, it is essential to accurately determine their diffusive properties. To do so, we propose a machine learning method to characterize…

Soft Condensed Matter · Physics 2023-11-29 Borja Requena , Sergi Masó , Joan Bertran , Maciej Lewenstein , Carlo Manzo , Gorka Muñoz-Gil

Most social, technological and biological networks are embedded in a finite dimensional space, and the distance between two nodes influences the likelihood that they link to each other. Indeed, in social systems, the chance that two…

Physics and Society · Physics 2018-06-27 Paul Balister , Chaoming Song , Oliver Riordan , Bela Bollobas , Albert-Laszlo Barabasi

Normal and anomalous diffusion are ubiquitous in many complex systems [1] . Here, we define a time and space generalized diffusion equation (GDE), which uses fractional-time derivatives and transformed d-path Laplacian operators on…

Physics and Society · Physics 2022-02-02 Fernando Diaz-Diaz , Ernesto Estrada

Dynamic networks are used in a variety of fields to represent the structure and evolution of the relationships between entities. We present a model which embeds longitudinal network data as trajectories in a latent Euclidean space. A Markov…

Methodology · Statistics 2020-05-19 Daniel K. Sewell , Yuguo Chen

In bacteria, regulatory proteins search for a specific DNA binding target via "facilitated diffusion": a series of rounds of 3D diffusion in the cytoplasm, and 1D linear diffusion along the DNA contour. Using large scale Brownian dynamics…

Biological Physics · Physics 2013-09-05 C. A. Brackley , M. E. Cates , D. Marenduzzo

The lack of analytical models describing diffusion time dependence at intermediate time scales in complex tissue microstructure limits the accurate quantification of extracellular diffusivity and tissue microstructure. We introduce TRACED,…