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Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Single-shot imaging with femtosecond X-ray lasers is a powerful measurement technique that can achieve both high spatial and temporal resolution. However, its accuracy has been severely limited by the difficulty of applying conventional…

Fluorescence lifetime imaging microscopy (FLIM) systems are limited by their slow processing speed, low signal-to-noise ratio (SNR), and expensive and challenging hardware setups. In this work, we demonstrate applying a denoising…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Varun Mannam , Yide Zhang , Xiaotong Yuan , Takashi Hato , Pierre C. Dagher , Evan L. Nichols , Cody J. Smith , Kenneth W. Dunn , Scott Howard

Imaging through scattering is a pervasive and difficult problem in many biological applications. The high background and the exponentially attenuated target signals due to scattering fundamentally limits the imaging depth of fluorescence…

Signal Processing · Electrical Eng. & Systems 2023-12-11 Jeffrey Alido , Joseph Greene , Yujia Xue , Guorong Hu , Yunzhe Li , Mitchell Gilmore , Kevin J. Monk , Brett T. DiBenedictis , Ian G. Davison , Lei Tian

Fluorescence Lifetime Imaging (FLI) is a critical molecular imaging modality that provides unique information about the tissue microenvironment, which is invaluable for biomedical applications. FLI operates by acquiring and analyzing photon…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Ismail Erbas , Vikas Pandey , Navid Ibtehaj Nizam , Nanxue Yuan , Amit Verma , Margarida Barosso , Xavier Intes

Biomedical photoacoustic tomography, which can provide high resolution 3D soft tissue images based on the optical absorption, has advanced to the stage at which translation from the laboratory to clinical settings is becoming possible. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Andreas Hauptmann , Ben Cox

By circumventing the resolution limitations of optics, coherent diffractive imaging (CDI) and ptychography are making their way into scientific fields ranging from X-ray imaging to astronomy. Yet, the need for time consuming iterative phase…

Computational Physics · Physics 2023-10-13 Oliver Hoidn , Aashwin Ananda Mishra , Apurva Mehta

Deep learning-based methods in computational microscopy have been shown to be powerful but in general face some challenges due to limited generalization to new types of samples and requirements for large and diverse training data. Here, we…

Image and Video Processing · Electrical Eng. & Systems 2022-06-13 Luzhe Huang , Xilin Yang , Tairan Liu , Aydogan Ozcan

Hallucinating high frequency image details in single image super-resolution is a challenging task. Traditional super-resolution methods tend to produce oversmoothed output images due to the ambiguity in mapping between low and high…

Computer Vision and Pattern Recognition · Computer Science 2017-01-27 Libin Sun , James Hays

Magnetic resonance imaging (MRI) is extensively used for diagnosis and image-guided therapeutics. Due to hardware, physical and physiological limitations, acquisition of high-resolution MRI data takes long scan time at high system cost, and…

Medical Physics · Physics 2018-10-17 Qing Lyu , Chenyu You , Hongming Shan , Ge Wang

Super-resolution algorithms often struggle with images from surveillance environments due to adverse conditions such as unknown degradation, variations in pose, irregular illumination, and occlusions. However, acquiring multiple images,…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Marcelo dos Santos , Rayson Laroca , Rafael O. Ribeiro , João C. Neves , David Menotti

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Cameras in modern devices such as smartphones, satellites and medical equipment are capable of capturing very high resolution images and videos. Such high-resolution data often need to be processed by deep learning models for cancer…

Computer Vision and Pattern Recognition · Computer Science 2022-12-07 Arian Bakhtiarnia , Qi Zhang , Alexandros Iosifidis

With the advent of microsphere assisted microscopy in 2011, this technique emerged as a simple and easy way to obtain optical super-resolution. Although the possible mechanisms of imaging by microspheres are debated in the literature, most…

Optics · Physics 2015-08-27 Navid Farahi

With the recent advancement in deep learning, we have witnessed a great progress in single image super-resolution. However, due to the significant information loss of the image downscaling process, it has become extremely challenging to…

Computer Vision and Pattern Recognition · Computer Science 2018-04-11 Zhifei Zhang , Zhaowen Wang , Zhe Lin , Hairong Qi

We propose a deep learning method for single image super-resolution (SR). Our method directly learns an end-to-end mapping between the low/high-resolution images. The mapping is represented as a deep convolutional neural network (CNN) that…

Computer Vision and Pattern Recognition · Computer Science 2015-08-03 Chao Dong , Chen Change Loy , Kaiming He , Xiaoou Tang

Modern lidar systems can produce not only dense point clouds but also 360 degrees low-resolution images. This advancement facilitates the application of deep learning (DL) techniques initially developed for conventional RGB cameras and…

Robotics · Computer Science 2025-04-18 Sier Ha , Honghao Du , Xianjia Yu , Jian Song , Tomi Westerlund

The most sophisticated existing methods to generate 3D isotropic super-resolution (SR) from non-isotropic electron microscopy (EM) are based on learned dictionaries. Unfortunately, none of the existing methods generate practically…

Computer Vision and Pattern Recognition · Computer Science 2017-06-13 Larissa Heinrich , John A. Bogovic , Stephan Saalfeld

Light-field microscopy (LFM) enables rapid volumetric imaging through single-frame acquisition and fast 3D reconstruction algorithms. The high speed and low phototoxicity of LFM make it highly suitable for real-time 3D fluorescence imaging,…

Optics · Physics 2025-02-24 Bohan Qu , Zhouyu Jin , You Zhou , Bo Xiong , Xun Cao

Recent progress in single-image super-resolution (SISR) has achieved remarkable performance, yet the computational costs of these methods remain a challenge for deployment on resource-constrained devices. In particular, transformer-based…

Computer Vision and Pattern Recognition · Computer Science 2024-10-22 Gang Wu , Junjun Jiang , Junpeng Jiang , Xianming Liu
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