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In this survey article, we present two applications of surface curvatures in theoretical physics. The first application arises from biophysics in the study of the shape of cell vesicles involving the minimization of a mean curvature type…

Mathematical Physics · Physics 2024-06-14 Yisong Yang

The Helfrich energy is commonly used to model the elastic bending energy of lipid bilayers in membrane mechanics. The governing differential equations for certain geometric characteristics of the shape of the membrane can be obtained by…

Numerical Analysis · Mathematics 2020-05-27 P. Rangamani , A. Behzadan , M. Holst

We address the geometric Cauchy problem for surfaces associated to the membrane shape equation describing equilibrium configurations of vesicles formed by lipid bilayers. This is the Euler-Lagrange equation of the Canham-Helfrich-Evans…

Differential Geometry · Mathematics 2014-11-18 Gary R. Jensen , Emilio Musso , Lorenzo Nicolodi

The deformation of cellular membranes regulates trafficking processes, such as exocytosis and endocytosis. Classically, the Helfrich continuum model is used to characterize the forces and mechanical parameters that cells tune to accomplish…

Quantitative Methods · Quantitative Biology 2022-06-14 Sage Malingen , Padmini Rangamani

Membranes holomorphically embedded in flat noncompact space are constructed in terms of the degrees of freedom of an infinite collection of 0-branes. To each holomorphic curve we associate infinite-dimensional matrices which are static…

High Energy Physics - Theory · Physics 2008-11-26 Lorenzo Cornalba , Washington Taylor

Functionals involving surface curvature are important across a range of scientific disciplines, and their extrema are representative of physically meaningful objects such as atomic lattices and biomembranes. Inspired in particular by the…

Differential Geometry · Mathematics 2020-01-31 Anthony Gruber , Magdalena Toda , Hung Tran

Biomembranes and vesicles consisting of multiple phases can attain a multitude of shapes, undergoing complex shape transitions. We study a Cahn--Hilliard model on an evolving hypersurface coupled to Navier--Stokes equations on the surface…

Numerical Analysis · Mathematics 2019-11-01 John W. Barrett , Harald Garcke , Robert Nürnberg

Biomembranes play a central role in various phenomena like locomotion of cells, cell-cell interactions, packaging of nutrients, and in maintaining organelle morphology and functionality. During these processes, the membranes undergo…

Quantitative Methods · Quantitative Biology 2021-12-01 Debabrata Auddya , Xiaoxuan Zhang , Rahul Gulati , Ritvik Vasan , Krishna Garikipati , Padmini Rangamani , Shiva Rudraraju

A model describing cell membranes as optimal shapes with regard to the $L^2$-deficit of their mean curvature to a given constant called spontaneous curvature is considered. It is shown that the corresponding energy functional is lower…

Differential Geometry · Mathematics 2023-11-01 Christian Scharrer

The purpose of this paper is to study the shapes and stabilities of bio-membranes within the framework of exterior differential forms. After a brief review of the current status in theoretical and experimental studies on the shapes of…

Soft Condensed Matter · Physics 2007-05-23 Z. C. Tu , Z. C. Ou-Yang

In this work, we study a phase-field model for curvature-driven pattern formation in biomembranes. The model is derived as a gradient flow of an energy functional that approximates the two-phase Canham--Helfrich energy. This leads to a…

Analysis of PDEs · Mathematics 2025-11-27 Patrik Knopf , Anastasija Pešić , Dennis Trautwein

Motivated by recent experimental work on multicomponent lipid membranes supported by colloidal scaffolds, we report an exhaustive theoretical investigation of the equilibrium configurations of binary mixtures on curved substrates. Starting…

Soft Condensed Matter · Physics 2018-09-12 Piermarco Fonda , Melissa Rinaldin , Daniela J. Kraft , Luca Giomi

The shapes of cell membranes are largely regulated by membrane associated, curvature active, proteins. We use a numerical model of the membrane with elongated membrane inclusions, recently developed by us, which posses spontaneous…

Biological Physics · Physics 2013-02-08 N. Ramakrishnan , P. B. Sunil Kumar , John H. Ipsen

Parametric finite elements lead to very efficient numerical methods for surface evolution equations. We introduce several computational techniques for curvature driven evolution equations based on a weak formulation for the mean curvature.…

Numerical Analysis · Mathematics 2020-01-17 John W. Barrett , Harald Garcke , Robert Nürnberg

An integrated mechanical model for fiber-laden membranes is presented and representative predictions of relevance to cellulose ordering and orientation in the plant cell wall are presented. The model describes nematic liquid crystalline…

Biological Physics · Physics 2009-06-24 Y. K. Murugesan , A. D. Rey

We consider membranes as fluid deformable surface and allow for higher order geometric terms in the bending energy. The evolution equations are derived and numerically solved using surface finite elements. The higher order geometric terms…

Soft Condensed Matter · Physics 2024-12-19 Jan Magnus Sischka , Ingo Nitschke , Axel Voigt

Consider a homogenous fluid membrane described by the Helfrich-Canham energy, quadratic in the mean curvature of the membrane surface. The shape equation that determines equilibrium configurations is fourth order in derivatives and cubic in…

Soft Condensed Matter · Physics 2009-11-11 Riccardo Capovilla , Jemal Guven , Efrain Rojas

The quantitative understanding of membranes is still rooted in work performed in the 1970s by Helfrich and others, concerning amphiphilic bilayers. However, most biological membranes contain a wide variety of nonamphiphilic molecules too.…

Soft Condensed Matter · Physics 2014-06-10 Richard G. Morris

The Canham-Helfrich-Evans models of biomembranes consist of a family of geometric constrained variational problems. In this article, we compare two classes of numerical methods for these variational problems based on piecewise linear (PL)…

Numerical Analysis · Mathematics 2020-03-31 Jingmin Chen , Thomas Yu , Patrick Brogan , Robert Kusner , Yilin Yang , Andrew Zigerelli

Variational principles are developed within the framework of a spinor representation of the surface geometry to examine the equilibrium properties of a membrane or interface. This is a far-reaching generalization of the Weierstrass-Enneper…

Soft Condensed Matter · Physics 2012-02-17 Jemal Guven , Pablo Vázquez-Montejo
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