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We propose a supervised machine learning approach for boosting existing signal and image recovery methods and demonstrate its efficacy on example of image reconstruction in computed tomography. Our technique is based on a local nonlinear…

Computer Vision and Pattern Recognition · Computer Science 2013-12-02 Joseph Shtok , Michael Zibulevsky , Michael Elad

Histopathological examination of surgical biopsies, such as in glioma and glioblastoma resection, is hindered in current clinical practice by the long times required for the laboratory analysis and pathological screening, typically taking…

This paper discusses the reconstruction of partially sampled spectrum-images to accelerate the acquisition in scanning transmission electron microscopy (STEM). The problem of image reconstruction has been widely considered in the literature…

Image and Video Processing · Electrical Eng. & Systems 2020-02-05 Etienne Monier , Thomas Oberlin , Nathalie Brun , Xiaoyan Li , Marcel Tencé , Nicolas Dobigeon

The number of photons available by coherent X-ray scattering from a single biomolecule is considerably less because of the extremely small elastic-scattering cross-section and low damage threshold. Even with a high X-ray flux of 3 x 10to 12…

Optics · Physics 2009-11-13 Tsumoru Shintake

Holographic microscopy presents challenges for color reproduction due to the usage of narrow-band illumination sources, which especially impacts the imaging of stained pathology slides for clinical diagnoses. Here, an accurate color…

Medical Physics · Physics 2019-03-06 Yibo Zhang , Tairan Liu , Yujia Huang , Da Teng , Yinxu Bian , Yichen Wu , Yair Rivenson , Alborz Feizi , Aydogan Ozcan

Several approaches have been proposed to solve the spectral unmixing problem in hyperspectral image analysis. Among them the use of sparse regression techniques aims to characterize the abundances in pixels based on a large library of…

Image and Video Processing · Electrical Eng. & Systems 2021-02-12 L. C. Ayres , S. J. M. de Almeida , J. C. M. Bermudez , R. A. Borsoi

Multispectral computed tomography (CT) enables advanced material characterization by acquiring energy-resolved projection data. However, since the incoming X-ray flux is be distributed across multiple narrow energy bins, the photon count…

It has previously been demonstrated that model-based reconstruction methods relying on a priori knowledge of the imaging point spread function (PSF) coupled to sparsity priors on the object to image can provide super-resolution in…

Image and Video Processing · Electrical Eng. & Systems 2019-10-02 Sergey Vilov , Bastien Arnal , Eliel Hojman , Yonina C. Eldar , Ori Katz , Emmanuel Bossy

The hyperspectral X-ray imaging has been long sought in various fields from material analysis to medical diagnosis. Here we propose a new semiconductor detector structure to realize energy-resolved imaging at potentially low cost. The…

Instrumentation and Detectors · Physics 2019-07-26 Tengfei Yan , Chunlei Yang , Xiaodong Cui

A novel phase retrieval algorithm for broadband hyperspectral phase imaging from noisy intensity observations is proposed. It utilizes advantages of the Fourier Transform spectroscopy in the self-referencing optical setup and provides,…

Image and Video Processing · Electrical Eng. & Systems 2020-06-03 Igor Shevkunov , Vladimir Katkovnik , Karen Egiazarian

Optoacoustic tomography image reconstruction has been a problem of interest in recent years. By exploiting the exceptional generative power of the recently proposed diffusion models we consider a scheme which is based on a conditional…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Martin G. Gonzalez , Matias Vera , Leonardo Rey Vega

Idier et al. [IEEE Trans. Comput. Imaging 4(1), 2018] propose a method which achieves superresolution in the microscopy setting by leveraging random speckle illumination and knowledge about statistical second order moments for the…

Signal Processing · Electrical Eng. & Systems 2022-02-02 Osman Asif Malik , Venkatalakshmi Vyjayanthi Narumanchi , Stephen Becker , Todd W. Murray

SPECT (Single-photon Emission Computerized Tomography) and PET (Positron Emission Tomography) are essential medical imaging tools, for which the sampling angle number, scan time should be chosen carefully to compromise between image quality…

Medical Physics · Physics 2015-06-16 Xiaolin Zhou , Minkai Yun , Xuexiang Cao , Shuangquan Liu , Lu Wang , Xianchao Huang , Long Wei

Structured illumination can reject out-of-focus signal from a sample, enabling high-speed and high-contrast imaging over large areas with widefield detection optics. Currently, this optical-sectioning technique is limited by image…

An efficient computational approach for optimal reconstruction of binary-type images suitable for models in various applications including biomedical imaging is developed and validated. The methodology includes derivative-free optimization…

Optimization and Control · Mathematics 2022-09-27 Paul R. Arbic , Vladislav Bukshtynov

Hyperspectral imaging is useful for applications ranging from medical diagnostics to agricultural crop monitoring; however, traditional scanning hyperspectral imagers are prohibitively slow and expensive for widespread adoption. Snapshot…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Kristina Monakhova , Kyrollos Yanny , Neerja Aggarwal , Laura Waller

Spectral CT has great potential for a variety of clinical applications due to the improved material discrimination with respect to conventional CT. Many clinical and preclinical spectral CT systems have two spectral channels for dual-energy…

Medical Physics · Physics 2020-10-17 Matthew Tivnan , Wenying Wang , J. Webster Stayman

Filtered diode array spectrometers are routinely employed to infer the temporal evolution of spectral power from x-ray sources, but uniquely extracting spectral content from a finite set of broad, spectrally overlapping channel spectral…

Computational Physics · Physics 2020-08-03 G. E. Kemp , M. S. Rubery , C. D. Harris , M. J. May , K. Widmann , R. F. Heeter , S. B. Libby , M. B. Schneider , B. E. Blue

Hyperspectral 3D imaging enables the capture of dense spectral information and scene geometry but has traditionally been confined to narrow spectral windows, typically the visible range. In this work, we introduce a broadband hyperspectral…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Suhyun Shin , Yunseong Moon , Ryota Maeda , David Lindell , Kyros Kutulacos , Seung-Hwan Baek

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

Quantum Physics · Physics 2026-01-15 Alberto Paniate , Giuseppe Ortolano , Sarika Soman , Marco Genovese , Ivano Ruo-Berchera