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Motivation: Understanding the spatial architecture of tissues is essential for decoding the complex interactions within cellular ecosystems and their implications for disease pathology and clinical outcomes. Recent advances in multiplex…

Quantitative Methods · Quantitative Biology 2025-04-28 Junsouk Choi , Jian Kang , Veerabhadran Baladandayuthapani

Multiplexed immunofluorescence provides an unprecedented opportunity for studying specific cell-to-cell and cell microenvironment interactions. We employ graph neural networks to combine features obtained from tissue morphology with…

Image and texture synthesis is a challenging task that has long been drawing attention in the fields of image processing, graphics, and machine learning. This problem consists of modelling the desired type of images, either through training…

Computer Vision and Pattern Recognition · Computer Science 2016-09-26 Yi Ren , Yaniv Romano , Michael Elad

Image registration is a fundamental medical image analysis task. Ideally, registration should focus on aligning semantically corresponding voxels, i.e., the same anatomical locations. However, existing methods often optimize similarity…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Lin Tian , Zi Li , Fengze Liu , Xiaoyu Bai , Jia Ge , Le Lu , Marc Niethammer , Xianghua Ye , Ke Yan , Daikai Jin

Diffusion models have recently been employed to generate high-quality images, reducing the need for manual data collection and improving model generalization in tasks such as object detection, instance segmentation, and image perception.…

Computer Vision and Pattern Recognition · Computer Science 2024-12-03 You Li , Fan Ma , Yi Yang

Soft X-ray tomography provides detailed structural insight into whole cells but is hindered by experimental artifacts such as the missing wedge and by limited availability of annotated datasets. We present SimAQ, a simulation pipeline that…

Quantitative Methods · Quantitative Biology 2026-05-21 Jacob Egebjerg , Daniel Wüstner

Synthesizing missing modalities in multi-modal magnetic resonance imaging (MRI) is vital for ensuring diagnostic completeness, particularly when full acquisitions are infeasible due to time constraints, motion artifacts, and patient…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Yue Zhang , Zhizheng Zhuo , Siyao Xu , Shan Lv , Zhaoxi Liu , Jun Qiu , Qiuli Wang , Yaou Liu , S. Kevin Zhou

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

Vision-aided wireless sensing is emerging as a cornerstone of 6G mobile computing. While data-driven approaches have advanced rapidly, establishing a precise geometric correspondence between ego-centric visual data and radio propagation…

Signal Processing · Electrical Eng. & Systems 2026-01-28 Yingzhe Mao , Chao Zou , Yanqun Tang

The quantification of synapses is instrumental to measure the evolution of synaptic densities of neurons under the effect of some physiological conditions, neuronal diseases or even drug treatments. However, the manual quantification of…

Computer Vision and Pattern Recognition · Computer Science 2015-07-29 Gadea Mata , Jónathan Heras , Miguel Morales , Ana Romero , Julio Rubio

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

We present a new approach to the simulation and analysis of immune system behavior. The simulations that can be done with our software package called SIMMUNE are based on immunological data that describe the behavior of immune system agents…

Multiagent Systems · Computer Science 2007-05-23 M. Meier-Schellersheim , G. Mack

Analyzing microscopy images to extract biological object properties (e.g., their morphological organization, temporal dynamics, and population density) is fundamental to various biomedical research. Yet conducting this manually is costly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-15 Xiaofei Hui , Haoxuan Qu , Hossein Rahmani , Shuohong Wang , Jeff W. Lichtman , Jun Liu

Label scarcity remains a major challenge in deep learning-based medical image segmentation. Recent studies use strong-weak pseudo supervision to leverage unlabeled data. However, performance is often hindered by inconsistencies between…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Zhiqiang Shen , Peng Cao , Xiaoli Liu , Jinzhu Yang , Osmar R. Zaiane

We introduce Synapse motivated by the needs to estimate and emulate workload execution characteristics on high-performance and distributed heterogeneous resources. Synapse has a platform independent application profiler, and the ability to…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-08-03 Andre Merzky , Shantenu Jha

Automated cell segmentation in microscopy images is essential for biomedical research, yet conventional methods are labor-intensive and prone to error. While deep learning-based approaches have proven effective, they often require large…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Rüveyda Yilmaz , Kaan Keven , Yuli Wu , Johannes Stegmaier

Medical image registration and segmentation are critical tasks for several clinical procedures. Manual realisation of those tasks is time-consuming and the quality is highly dependent on the level of expertise of the physician. To mitigate…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Lihao Liu , Zhening Huang , Pietro Liò , Carola-Bibiane Schönlieb , Angelica I. Aviles-Rivero

In this work, we present SynTable, a unified and flexible Python-based dataset generator built using NVIDIA's Isaac Sim Replicator Composer for generating high-quality synthetic datasets for unseen object amodal instance segmentation of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Zhili Ng , Haozhe Wang , Zhengshen Zhang , Francis Tay Eng Hock , Marcelo H. Ang

Camouflaged objects that blend into natural scenes pose significant challenges for deep-learning models to detect and synthesize. While camouflaged object detection is a crucial task in computer vision with diverse real-world applications,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Haichao Zhang , Can Qin , Yu Yin , Yun Fu