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Automated synthesis of histology images has several potential applications in computational pathology. However, no existing method can generate realistic tissue images with a bespoke cellular layout or user-defined histology parameters. In…

Image and Video Processing · Electrical Eng. & Systems 2022-12-29 Srijay Deshpande , Muhammad Dawood , Fayyaz Minhas , Nasir Rajpoot

Conventional histopathology has long been essential for disease diagnosis, relying on visual inspection of tissue sections. Immunohistochemistry aids in detecting specific biomarkers but is limited by its single-marker approach, restricting…

Artificial intelligence (AI), machine learning, and deep learning (DL) methods are becoming increasingly important in the field of biomedical image analysis. However, to exploit the full potential of such methods, a representative number of…

We introduce a new AI-ready computational pathology dataset containing restained and co-registered digitized images from eight head-and-neck squamous cell carcinoma patients. Specifically, the same tumor sections were stained with the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-29 Parmida Ghahremani , Joseph Marino , Juan Hernandez-Prera , Janis V. de la Iglesia , Robbert JC Slebos , Christine H. Chung , Saad Nadeem

Artificial intelligence (AI) now enables automated interpretation of medical images for clinical use. However, AI's potential use for interventional images (versus those involved in triage or diagnosis), such as for guidance during surgery,…

Image and Video Processing · Electrical Eng. & Systems 2022-06-14 Cong Gao , Benjamin D. Killeen , Yicheng Hu , Robert B. Grupp , Russell H. Taylor , Mehran Armand , Mathias Unberath

In recent years, deep learning (DL) has shown great potential in the field of dermatological image analysis. However, existing datasets in this domain have significant limitations, including a small number of image samples, limited disease…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Ashish Sinha , Jeremy Kawahara , Arezou Pakzad , Kumar Abhishek , Matthieu Ruthven , Enjie Ghorbel , Anis Kacem , Djamila Aouada , Ghassan Hamarneh

Synthetic data has emerged as a promising source for 3D human research as it offers low-cost access to large-scale human datasets. To advance the diversity and annotation quality of human models, we introduce a new synthetic dataset,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Zhitao Yang , Zhongang Cai , Haiyi Mei , Shuai Liu , Zhaoxi Chen , Weiye Xiao , Yukun Wei , Zhongfei Qing , Chen Wei , Bo Dai , Wayne Wu , Chen Qian , Dahua Lin , Ziwei Liu , Lei Yang

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

Generating realistic tissue images with annotations is a challenging task that is important in many computational histopathology applications. Synthetically generated images and annotations are valuable for training and evaluating…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Srijay Deshpande , Fayyaz Minhas , Nasir Rajpoot

Multiplexed imaging data are revolutionizing our understanding of the composition and organization of tissues and tumors. A critical aspect of such tissue profiling is quantifying the spatial relationship relationships among cells at…

Quantitative Methods · Quantitative Biology 2024-05-06 Ajit J. Nirmal , Peter K. Sorger

Realistic simulations of experiments at large scale photon facilities, such as optical laser laboratories, synchrotrons, and free electron lasers, are of vital importance for the successful preparation, execution, and analysis of these…

We describe SynthPix, a synthetic image generator for Particle Image Velocimetry (PIV) with a focus on performance and parallelism on accelerators, implemented in JAX. SynthPix produces PIV image pairs from prescribed flow fields while…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-04-15 Antonio Terpin , Alan Bonomi , Francesco Banelli , Raffaello D'Andrea

Ultrasound (US) image stitching can expand the field-of-view (FOV) by combining multiple US images from varied probe positions. However, registering US images with only partially overlapping anatomical contents is a challenging task. In…

Image and Video Processing · Electrical Eng. & Systems 2024-11-12 Xing Yao , Runxuan Yu , Dewei Hu , Hao Yang , Ange Lou , Jiacheng Wang , Daiwei Lu , Gabriel Arenas , Baris Oguz , Alison Pouch , Nadav Schwartz , Brett C Byram , Ipek Oguz

The performance of medical image analysis systems is constrained by the quantity of high-quality image annotations. Such systems require data to be annotated by experts with years of training, especially when diagnostic decisions are…

Computer Vision and Pattern Recognition · Computer Science 2019-02-08 Siqi Liu , Eli Gibson , Sasa Grbic , Zhoubing Xu , Arnaud Arindra Adiyoso Setio , Jie Yang , Bogdan Georgescu , Dorin Comaniciu

Hyperspectral imaging has attracted significant attention to identify spectral signatures for image classification and automated pattern recognition in computer vision. State-of-the-art implementations of snapshot hyperspectral imaging rely…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Maksim Makarenko , Arturo Burguete-Lopez , Qizhou Wang , Fedor Getman , Silvio Giancola , Bernard Ghanem , Andrea Fratalocchi

Multiplex imaging is revolutionizing pathology by enabling the simultaneous visualization of multiple biomarkers within tissue samples, providing molecular-level insights that traditional hematoxylin and eosin (H&E) staining cannot provide.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-06 Hyun-Jic Oh , Junsik Kim , Zhiyi Shi , Yichen Wu , Yu-An Chen , Peter K Sorger , Hanspeter Pfister , Won-Ki Jeong

Multi-modal medical images provide complementary soft-tissue characteristics that aid in the screening and diagnosis of diseases. However, limited scanning time, image corruption and various imaging protocols often result in incomplete…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Yue Zhang , Chengtao Peng , Qiuli Wang , Dan Song , Kaiyan Li , S. Kevin Zhou

High content imaging is needed to catalogue the variety of cellular phenotypes and multi-cellular ecosystems present in metazoan tissues. We recently developed Iterative Bleaching Extends multi-pleXity (IBEX), an iterative immunolabeling…

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Registration of histological and mass spectrometry imaging (MSI) allows for more precise identification of structural changes and chemical interactions in tissue. With histology and MSI having entirely different image formation processes…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Kimberley M. Bird , Xujiong Ye , Alan M. Race , James M. Brown
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