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Reliable prediction of pediatric obesity can offer a valuable resource to providers, helping them engage in timely preventive interventions before the disease is established. Many efforts have been made to develop ML-based predictive models…

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

Statistical machine learning methods often face the challenge of limited data available from the population of interest. One remedy is to leverage data from auxiliary source populations, which share some conditional distributions or are…

Methodology · Statistics 2024-06-11 Hongxiang Qiu , Eric Tchetgen Tchetgen , Edgar Dobriban

Statistical estimation and inference for marginal hazard models with varying coefficients for multivariate failure time data are important subjects in survival analysis. A local pseudo-partial likelihood procedure is proposed for estimating…

Statistics Theory · Mathematics 2009-09-29 Jianwen Cai , Jianqing Fan , Haibo Zhou , Yong Zhou

In this paper we are interested in the prediction of preterm birth based on diagnosis codes from longitudinal EHR. We formulate the prediction problem as a supervised classification with noisy labels. Our base classifier is a Recurrent…

Machine Learning · Statistics 2018-12-07 Sabri Boughorbel , Fethi Jarray , Neethu Venugopal , Haithum Elhadi

Test data measured by medical instruments often carry imprecise ranges that include the true values. The latter are not obtainable in virtually all cases. Most learning algorithms, however, carry out arithmetical calculations that are…

Machine Learning · Computer Science 2020-07-27 Mei Wang , Jianwen Su , Haiqin Lu

We propose a sampling scheme suitable for reducing a data set prior to selecting a hypothesis with minimum empirical risk. The sampling only considers a subset of the ultimate (unknown) hypothesis set, but can nonetheless guarantee that the…

Machine Learning · Computer Science 2013-06-25 Paul Mineiro , Nikos Karampatziakis

We study the well known difficult problem of prediction in measurement error models. By targeting directly at the prediction interval instead of the point prediction, we construct a prediction interval by providing estimators of both the…

Methodology · Statistics 2024-05-20 Fei Jiang , Yanyuan Ma

Predicting an individual's risk of experiencing a future clinical outcome is a statistical task with important consequences for both practicing clinicians and public health experts. Modern observational databases such as electronic health…

Given the long follow-up periods that are often required for treatment or intervention studies, the potential to use surrogate markers to decrease the required follow-up time is a very attractive goal. However, previous studies have shown…

Methodology · Statistics 2016-08-12 Layla Parast , Tianxi Cai , Lu Tian

Extremile regression, as a least squares analog of quantile regression, is potentially useful tool for modeling and understanding the extreme tails of a distribution. However, existing extremile regression methods, as nonparametric…

Methodology · Statistics 2025-07-03 Rong Jiang , Keming Yu , Jiangfeng Wang

The accurate labeling of datasets is often both costly and time-consuming. Given an unlabeled dataset, programmatic weak supervision obtains probabilistic predictions for the labels by leveraging multiple weak labeling functions (LFs) that…

Machine Learning · Statistics 2025-08-07 Verónica Álvarez , Santiago Mazuelas , Steven An , Sanjoy Dasgupta

Overfitting, which happens when the number of parameters in a model is too large compared to the number of data points available for determining these parameters, is a serious and growing problem in survival analysis. While modern medicine…

Applications · Statistics 2017-09-13 ACC Coolen , JE Barrett , P Paga , CJ Perez-Vicente

Prior to clinical applications, it is critical that risk prediction models are evaluated in independent studies that did not contribute to model development. While prospective cohort studies provide a natural setting for model validation,…

Methodology · Statistics 2017-10-13 Parichoy Pal Choudhury , Anil K. Chaturvedi , Nilanjan Chatterjee

With the growing availability of large-scale biomedical data, it is often time-consuming or infeasible to directly perform traditional statistical analysis with relatively limited computing resources at hand. We propose a fast subsampling…

Methodology · Statistics 2023-05-18 Haixiang Zhang , Lulu Zuo , HaiYing Wang , Liuquan Sun

We propose a general semi-supervised inference framework focused on the estimation of the population mean. As usual in semi-supervised settings, there exists an unlabeled sample of covariate vectors and a labeled sample consisting of…

Methodology · Statistics 2018-08-15 Anru Zhang , Lawrence D. Brown , T. Tony Cai

While the volume of electronic health records (EHR) data continues to grow, it remains rare for hospital systems to capture dense physiological data streams, even in the data-rich intensive care unit setting. Instead, typical EHR records…

Machine Learning · Computer Science 2018-12-04 Satya Narayan Shukla , Benjamin M. Marlin

With the availability of massive amounts of data from electronic health records and registry databases, incorporating time-varying patient information to improve risk prediction has attracted great attention. To exploit the growing amount…

Applications · Statistics 2022-08-29 Yifei Sun , Sy Han Chiou , Colin O. Wu , Meghan McGarry , Chiung-Yu Huang

As cancer patient survival improves, late effects from treatment are becoming the next clinical challenge. Chemotherapy and radiotherapy, for example, potentially increase the risk of both morbidity and mortality from second malignancies…

Systemic risk measures have been shown to be predictive of financial crises and declines in real activity. Thus, forecasting them is of major importance in finance and economics. In this paper, we propose a new forecasting method for…

Methodology · Statistics 2025-04-23 Yannick Hoga