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Spiking neural networks (SNNs) are energy-efficient neural networks because of their spiking nature. However, as the spike firing rate of SNNs increases, the energy consumption does as well, and thus, the advantage of SNNs diminishes. Here,…

Machine Learning · Computer Science 2024-01-15 Kazuma Suetake , Takuya Ushimaru , Ryuji Saiin , Yoshihide Sawada

The identification of unlabelled neuronal electric signals is one of the most challenging open problems in neuroscience, widely known as Spike Sorting. Motivated to solve this problem, we propose a model-based approach within the mixture…

Applications · Statistics 2022-03-14 Alejandro Rodríguez-Collado , Cristina Rueda

A Spiking Neural Network (SNN) can be trained indirectly by first training an Artificial Neural Network (ANN) with the conventional backpropagation algorithm, then converting it into an SNN. The conventional rate-coding method for SNNs uses…

Neural and Evolutionary Computing · Computer Science 2021-06-15 Ming Zhang , Nenggan Zheng , De Ma , Gang Pan , Zonghua Gu

Identification of patterns from discrete data time-series for statistical inference, threat detection, social opinion dynamics, brain activity prediction has received recent momentum. In addition to the huge data size, the associated…

Machine Learning · Computer Science 2019-02-22 Ruochen Yang , Gaurav Gupta , Paul Bogdan

Rapid experimental advances now enable simultaneous electrophysiological recording of neural activity at single-cell resolution across large regions of the nervous system. Models of this neural network activity will necessarily increase in…

Neurons and Cognition · Quantitative Biology 2017-10-02 Andrea K. Barreiro , Cheng Ly

Spiking Neural Networks (SNNs), recognized as the third generation of neural networks, are known for their bio-plausibility and energy efficiency, especially when implemented on neuromorphic hardware. However, the majority of existing…

Neural and Evolutionary Computing · Computer Science 2024-07-02 Yi Jiang , Sen Lu , Abhronil Sengupta

Neurons in the intact brain receive a continuous and irregular synaptic bombardment from excitatory and inhibitory pre-synaptic neurons, which determines the firing activity of the stimulated neuron. In order to investigate the influence of…

Neurons and Cognition · Quantitative Biology 2017-05-23 Simona Olmi , David Angulo-Garcia , Alberto Imparato , Alessandro Torcini

Spike sorting is an essential process in neural recording, which identifies and separates electrical signals from individual neurons recorded by electrodes in the brain, enabling researchers to study how specific neurons communicate and…

Neurons and Cognition · Quantitative Biology 2025-12-23 Yimu Zhang , Dongqi Han , Yansen Wang , Zhenning Lv , Yu Gu , Dongsheng Li

Recurrently connected neuron populations play key roles in sensory perception and memory storage across various brain regions. While these populations are often assumed to encode information through firing rates, this method becomes…

Neurons and Cognition · Quantitative Biology 2025-09-05 Mauricio Girardi-Schappo , Leonard Maler , André Longtin

Spiking Neural Networks (SNNs) are highly energy-efficient due to event-driven, sparse computation, but their training is challenged by spike non-differentiability and trade-offs among performance, efficiency, and biological plausibility.…

Neural and Evolutionary Computing · Computer Science 2026-01-30 Zihan Huang , Zijie Xu , Yihan Huang , Shanshan Jia , Tong Bu , Yiting Dong , Wenxuan Liu , Jianhao Ding , Zhaofei Yu , Tiejun Huang

A main concern in cognitive neuroscience is to decode the overt neural spike train observations and infer latent representations under neural circuits. However, traditional methods entail strong prior on network structure and hardly meet…

Neurons and Cognition · Quantitative Biology 2019-11-22 Zhijie Chen , Junchi Yan , Longyuan Li , Xiaokang Yang

Modelling the dynamics of interactions in a neuronal ensemble is an important problem in functional connectivity research. One popular framework is latent factor models (LFMs), which have achieved notable success in decoding neuronal…

Methodology · Statistics 2023-05-18 Meixi Chen , Martin Lysy , David Moorman , Reza Ramezan

Does synchronization between action potentials from different neurons in the visual system play a substantial role in solving the binding problem? The binding problem can be studied quantitatively in the broader framework of the information…

Biological Physics · Physics 2007-05-23 Simon R. Schultz , Huw D. R. Golledge , Stefano Panzeri

This paper suggests a learning-theoretic perspective on how synaptic plasticity benefits global brain functioning. We introduce a model, the selectron, that (i) arises as the fast time constant limit of leaky integrate-and-fire neurons…

Neurons and Cognition · Quantitative Biology 2012-09-26 David Balduzzi , Michel Besserve

`Bursting', defined as periods of high frequency firing of a neuron separated by periods of quiescence, has been observed in various neuronal systems, both \textit{in vitro} and \textit{in vivo}. It has been associated with a range of…

Neurons and Cognition · Quantitative Biology 2018-06-20 E. Cotterill , S. J. Eglen

Imaging flow cytometry systems aim to analyze a huge number of cells or micro-particles based on their physical characteristics. The vast majority of current systems acquire a large amount of images which are used to train deep artificial…

Neural and Evolutionary Computing · Computer Science 2023-03-21 Muhammed Gouda , Steven Abreu , Alessio Lugnan , Peter Bienstman

Two-photon laser scanning microscopy is widely used in a quickly growing field of neuroscience. It is a fluorescence imaging technique that allows imaging of living tissue up to a very high depth to study inherent brain structure and…

Applications · Statistics 2018-02-15 Kyongche Kang , Jinsub Hong , Hannah Worrall

Novel materials and devices in photonics have the potential to revolutionize optical information processing, beyond conventional binary-logic approaches. Laser systems offer a rich repertoire of useful dynamical behaviors, including the…

Real-time analysis and classification of bio-signals measured using wearable devices is computationally costly and requires dedicated low-power hardware. One promising approach is to use spiking neural networks implemented using in-memory…

Signal Processing · Electrical Eng. & Systems 2022-09-07 Stefan Gerber , Marc Steiner , Maryada , Giacomo Indiveri , Elisa Donati

Mitochondrial calcium handling is a particularly active research area in the neuroscience field, as it plays key roles in the regulation of several functions of the central nervous system, such as synaptic transmission and plasticity,…

Neurons and Cognition · Quantitative Biology 2024-08-23 Roman Serrat , Alexandre Oliveira-Pinto , Giovanni Marsicano , Sandrine Pouvreau