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Non-Alcoholic Fatty Liver Disease (NAFLD) is becoming increasingly prevalent in the world population. Without diagnosis at the right time, NAFLD can lead to non-alcoholic steatohepatitis (NASH) and subsequent liver damage. The diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2020-09-23 Ananya Jana , Hui Qu , Puru Rattan , Carlos D. Minacapelli , Vinod Rustgi , Dimitris Metaxas

Non alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease, which can be predicted accurately to prevent advanced fibrosis and cirrhosis. While, a liver biopsy, the gold standard for NAFLD diagnosis, is…

Image and Video Processing · Electrical Eng. & Systems 2023-07-20 Yaran Chen , Xueyu Chen , Yu Han , Haoran Li , Dongbin Zhao , Jingzhong Li , Xu Wang

Non-alcoholic fatty liver disease (NAFLD) is a clinicopathological syndrome characterized by hepatic steatosis resulting from the exclusion of alcohol and other identifiable liver-damaging factors. It has emerged as a leading cause of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Shan Cao , Qunsheng Ruan , Qingfeng Wu , Weiqiang Lin

Non-alcoholic fatty liver disease (NAFLD) is one of the most widespread liver disorders on a global scale, posing a significant threat of progressing to more severe conditions like nonalcoholic steatohepatitis (NASH), liver fibrosis,…

Non-alcoholic fatty liver disease (NAFLD) is a prevalent chronic liver disorder characterized by the excessive accumulation of fat in the liver in individuals who do not consume significant amounts of alcohol, including risk factors like…

Quantitative Methods · Quantitative Biology 2023-11-16 Tahmina Sultana Priya , Fan Leng , Anthony C. Luehrs , Eric W. Klee , Alina M. Allen , Konstantinos N. Lazaridis , Danfeng , Yao , Shulan Tian

Accurate analysis of the fibrosis stage plays very important roles in follow-up of patients with chronic hepatitis B infection. In this paper, a deep learning framework is presented for automatically liver fibrosis prediction. On contrary…

Image and Video Processing · Electrical Eng. & Systems 2020-09-11 Jiali Liu , Wenxuan Wang , Tianyao Guan , Ningbo Zhao , Xiaoguang Han , Zhen Li

Non-invasive radiological-based lesion characterization and identification, e.g., to differentiate cancer subtypes, has long been a major aim to enhance oncological diagnosis and treatment procedures. Here we study a specific population of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Yuankai Huo , Jinzheng Cai , Chi-Tung Cheng , Ashwin Raju , Ke Yan , Bennett A. Landman , Jing Xiao , Le Lu , Chien-Hung Liao , Adam P. Harrison

Integrating deep learning with clinical expertise holds great potential for addressing healthcare challenges and empowering medical professionals with improved diagnostic tools. However, the need for annotated medical images is often an…

Computer Vision and Pattern Recognition · Computer Science 2023-11-16 Romain Hardy , Joe Klepich , Ryan Mitchell , Steve Hall , Jericho Villareal , Cornelia Ilin

Liver fibrosis poses a substantial challenge in clinical practice, emphasizing the necessity for precise liver segmentation and accurate disease staging. Based on the CARE Liver 2025 Track 4 Challenge, this study introduces a multi-task…

Computer Vision and Pattern Recognition · Computer Science 2026-02-11 Boya Wang , Ruizhe Li , Chao Chen , Xin Chen

Objectives: To develop and evaluate a radiomics machine learning model for detecting liver fibrosis on CT of the liver. Methods: For this retrospective, single-centre study, radiomic features were extracted from Regions of Interest (ROIs)…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Jay J. Yoo , Khashayar Namdar , Sean Carey , Sandra E. Fischer , Chris McIntosh , Farzad Khalvati , Patrik Rogalla

Histological scoring is essential for diagnosing Non-Alcoholic Fatty Liver Disease (NAFLD), yet its automation remains challenging due to the high annotation cost and negative transfer among the strongly correlated NAFLD Activity Score…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Youhan Huang , Jiajun Li , Yilin Fang , Shuai Wang , Chuheng Li

Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Bowen Li , Ke Yan , Dar-In Tai , Yuankai Huo , Le Lu , Jing Xiao , Adam P. Harrison

Non-alcoholic fatty pancreas disease (NAFPD) is an underdiagnosed condition associated with metabolic syndrome, insulin resistance, and increased risk of pancreatic cancer. Diagnosis typically relies on subjective visual assessment of…

Objectives: The role of advanced diffusion-weighted imaging (DWI) in chronic liver disease (CLD) has not been fully studied. Chronic liver disease (CLD) is a progressive deterioration of liver functions, caused by one or more etiology. This…

Tissues and Organs · Quantitative Biology 2025-09-10 Jiqing Huang , Benjamin Leporq , Valérie Hervieu , Sophie Gaillard , Jerome Dumortier , Olivier Beuf , Hélène Ratiney

With the success of deep learning-based methods applied in medical image analysis, convolutional neural networks (CNNs) have been investigated for classifying liver disease from ultrasound (US) data. However, the scarcity of available…

Image and Video Processing · Electrical Eng. & Systems 2021-12-21 Hui Che , Sumana Ramanathan , David Foran , John L Nosher , Vishal M Patel , Ilker Hacihaliloglu

Pulmonary fibrosis is a devastating chronic lung disease that causes irreparable lung tissue scarring and damage, resulting in progressive loss in lung capacity and has no known cure. A critical step in the treatment and management of…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Alexander Wong , Jack Lu , Adam Dorfman , Paul McInnis , Mahmoud Famouri , Daniel Manary , James Ren Hou Lee , Michael Lynch

In chronic liver disease, liver fibrosis develops as excessive deposition of extracellular matrix macromolecules, predominantly collagens, progressively form fibrous scars that disrupt the hepatic architecture, and fibrosis, iron, and fat…

With the development of radiomics, noninvasive diagnosis like ultrasound (US) imaging plays a very important role in automatic liver fibrosis diagnosis (ALFD). Due to the noisy data, expensive annotations of US images, the application of…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Lufei Gao , Ruisong Zhou , Changfeng Dong , Cheng Feng , Zhen Li , Xiang Wan , Li Liu

Transfer learning and joint learning approaches are extensively used to improve the performance of Convolutional Neural Networks (CNNs). In medical imaging applications in which the target dataset is typically very small, transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2020-05-26 Michal Heker , Hayit Greenspan

Liver fibrosis represents the accumulation of excessive extracellular matrix caused by sustained hepatic injury. It disrupts normal lobular architecture and function, increasing the chances of cirrhosis and liver failure. Precise staging of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-01 Yang Zhou , Kunhao Yuan , Ye Wei , Jishizhan Chen
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