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In this paper, we propose a continuous-time stochastic intensity model, namely, two-phase dynamic contagion process(2P-DCP), for modelling the epidemic contagion of COVID-19 and investigating the lockdown effect based on the dynamic…

Physics and Society · Physics 2020-06-30 Zezhun Chen , Angelos Dassios , Valerie Kuan , Jia Wei Lim , Yan Qu , Budhi Surya , Hongbiao Zhao

This paper is based on the observation that, during Covid-19 epidemic, the choice of which individuals should be tested has an important impact on the effectiveness of selective confinement measures. This decision problem is closely related…

Physics and Society · Physics 2020-12-24 Matthias Pezzutto , Nicolas Bono Rossello , Luca Schenato , Emanuele Garone

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

Drug development is time-consuming and expensive. Repurposing existing drugs for new therapies is an attractive solution that accelerates drug development at reduced experimental costs, specifically for Coronavirus Disease 2019 (COVID-19),…

Biomolecules · Quantitative Biology 2022-02-11 Xiaoqin Pan , Xuan Lin , Dongsheng Cao , Xiangxiang Zeng , Philip S. Yu , Lifang He , Ruth Nussinov , Feixiong Cheng

The novel coronavirus (COVID-19), a highly infectious respiratory disease caused by the SARS-CoV-2 has emerged as an unprecedented healthcare crisis. The pandemic had a devastating impact on the health, well-being, and economy of the global…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Sonit Singh

The coronavirus disease 2019 (COVID-19) pandemic has exerted a profound impact on patients with end-stage renal disease relying on kidney dialysis to sustain their lives. Motivated by a request by the U.S. Centers for Medicare & Medicaid…

Methodology · Statistics 2022-09-02 Wenbo Wu , John D. Kalbfleisch , Jeremy M. G. Taylor , Jian Kang , Kevin He

In the present article we introduce an epidemiological model for the investigation of the spread of epidemics caused by viruses. The model is applied specifically to COVID-19, the disease caused by the SARS-Cov-2 virus (aka "novel…

Populations and Evolution · Quantitative Biology 2020-04-10 Rodrigo A. Schulz , Carlos H. Coimbra-Araújo , Samuel W. S. Costiche

To strengthen inferences meta analyses are commonly used to summarize information from a set of independent studies. In some cases, though, the data may not satisfy the assumptions underlying the meta analysis. Using three Bayesian methods…

Applications · Statistics 2022-04-07 Dexter Cahoy , Joseph Sedransk

A prompt severity assessment model of patients confirmed for having infectious diseases could enable efficient diagnosis while alleviating burden on the medical system. This study aims to develop a SARS-CoV-2 severity assessment model and…

Machine Learning · Computer Science 2022-02-18 Min Sue Park , Hyeontae Jo , Haeun Lee , Se Young Jung , Hyung Ju Hwang

The spread of COVID-19 caused by the recently discovered SARS-CoV-2 virus has become a worldwide problem with devastating consequences. To slow down the spread of the pandemic, mass quarantines have been implemented globally, provoking…

Coronavirus case-count data has influenced government policies and drives most epidemiological forecasts. Limited testing is cited as the key driver behind minimal information on the COVID-19 pandemic. While expanded testing is laudable,…

Methodology · Statistics 2022-09-22 Walter Dempsey

Group testing allows saving chemical reagents, analysis time, and costs, by testing pools of samples instead of individual samples. We introduce a class of group testing protocols with small dilution, suited to operate even at high…

Physics and Society · Physics 2022-03-09 Marco Chiani , Gianluigi Liva , Enrico Paolini

The 2019 coronavirus disease (COVID-19) became a worldwide pandemic with currently no effective antiviral drug except treatments for symptomatic therapy. Flux balance analysis is an efficient method to analyze metabolic networks. It allows…

Molecular Networks · Quantitative Biology 2021-11-12 Ali Kishk , Maria Pires Pacheco , Thomas Sauter

Mathematical models of SARS-CoV-2 spread are used for guiding the design of mitigation steps aimed at containing and decelerating the contagion, and at identifying impending breaches of health care system surge capacity. The challenges of…

Populations and Evolution · Quantitative Biology 2020-06-17 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Coronavirus (COVID-19) emerged towards the end of 2019. World Health Organization (WHO) was identified it as a global epidemic. Consensus occurred in the opinion that using Computerized Tomography (CT) techniques for early diagnosis of…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Umut Ozkaya , Saban Ozturk , Mucahid Barstugan

This paper presents methods to choose individuals to test for infection during a pandemic such as COVID-19, characterized by high contagion and presence of asymptomatic carriers. The smart-testing ideas presented here are motivated by…

Machine Learning · Computer Science 2020-12-29 Yingfei Wang , Inbal Yahav , Balaji Padmanabhan

As of December 2020, the COVID-19 pandemic has infected over 75 million people, making it the deadliest pandemic in modern history. This study develops a novel compartmental epidemiological model specific to the SARS-CoV-2 virus and…

Populations and Evolution · Quantitative Biology 2021-11-19 Caden Lin

The SARS-CoV-2 coronavirus emerged in 2019, causing a COVID-19 pandemic that resulted in 7 million deaths out of 770 million reported cases over the next four years. The global health emergency called for unprecedented efforts to monitor…

The main purpose of this study is to develop a pipeline for COVID-19 detection from a big and challenging database of Computed Tomography (CT) images. The proposed pipeline includes a segmentation part, a lung extraction part, and a…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Kenan Morani

COVID-19 infection caused by SARS-CoV-2 pathogen is a catastrophic pandemic outbreak all over the world with exponential increasing of confirmed cases and, unfortunately, deaths. In this work we propose an AI-powered pipeline, based on the…