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Unsupervised anomaly detection (UAD) methods are trained with normal (or healthy) images only, but during testing, they are able to classify normal and abnormal (or disease) images. UAD is an important medical image analysis (MIA) method to…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 Yu Tian , Fengbei Liu , Guansong Pang , Yuanhong Chen , Yuyuan Liu , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro

Deep unsupervised representation learning has recently led to new approaches in the field of Unsupervised Anomaly Detection (UAD) in brain MRI. The main principle behind these works is to learn a model of normal anatomy by learning to…

Image and Video Processing · Electrical Eng. & Systems 2020-04-09 Christoph Baur , Stefan Denner , Benedikt Wiestler , Shadi Albarqouni , Nassir Navab

Unsupervised Anomaly Detection (UAD) with incremental training is crucial in industrial manufacturing, as unpredictable defects make obtaining sufficient labeled data infeasible. However, continual learning methods primarily rely on…

Computer Vision and Pattern Recognition · Computer Science 2024-01-03 Jiaqi Liu , Kai Wu , Qiang Nie , Ying Chen , Bin-Bin Gao , Yong Liu , Jinbao Wang , Chengjie Wang , Feng Zheng

Unsupervised anomaly detection (UAD) aims to detect anomalies without labeled data, a necessity in many machine learning applications where anomalous samples are rare or not available. Most state-of-the-art methods fall into two categories:…

Machine Learning · Computer Science 2025-07-30 Nicolas Pinon , Carole Lartizien

Universal anomaly detection still remains a challenging problem in machine learning and medical image analysis. It is possible to learn an expected distribution from a single class of normative samples, e.g., through epistemic uncertainty…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Johanna P. Müller , Matthew Baugh , Jeremy Tan , Mischa Dombrowski , Bernhard Kainz

Contrastive Analysis (CA) detects anomalies by contrasting patterns unique to a target group (e.g., unhealthy subjects) from those in a background group (e.g., healthy subjects). In the context of brain MRIs, existing CA approaches rely on…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Cristiano Patrício , Carlo Alberto Barbano , Attilio Fiandrotti , Riccardo Renzulli , Marco Grangetto , Luis F. Teixeira , João C. Neves

Contrastive learning, which aims to capture general representation from unlabeled images to initialize the medical analysis models, has been proven effective in alleviating the high demand for expensive annotations. Current methods mainly…

Computer Vision and Pattern Recognition · Computer Science 2022-08-18 Huai Chen , Renzhen Wang , Xiuying Wang , Jieyu Li , Qu Fang , Hui Li , Jianhao Bai , Qing Peng , Deyu Meng , Lisheng Wang

Unsupervised anomaly detection (UAD) alleviates large labeling efforts by training exclusively on unlabeled in-distribution data and detecting outliers as anomalies. Generally, the assumption prevails that large training datasets allow the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-29 Felix Meissen , Johannes Getzner , Alexander Ziller , Özgün Turgut , Georgios Kaissis , Martin J. Menten , Daniel Rueckert

Unsupervised anomaly detection (UAD) aims to find anomalous images by optimising a detector using a training set that contains only normal images. UAD approaches can be based on reconstruction methods, self-supervised approaches, and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-23 Yu Tian , Guansong Pang , Yuyuan Liu , Chong Wang , Yuanhong Chen , Fengbei Liu , Rajvinder Singh , Johan W Verjans , Mengyu Wang , Gustavo Carneiro

Most advanced unsupervised anomaly detection (UAD) methods rely on modeling feature representations of frozen encoder networks pre-trained on large-scale datasets, e.g. ImageNet. However, the features extracted from the encoders that are…

Computer Vision and Pattern Recognition · Computer Science 2023-10-25 Jia Guo , Shuai Lu , Lize Jia , Weihang Zhang , Huiqi Li

Unsupervised anomaly detection aims to detect defective parts of a sample by having access, during training, to a set of normal, i.e. defect-free, data. It has many applications in fields, such as industrial inspection or medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Robin Trombetta , Carole Lartizien

The essence of unsupervised anomaly detection is to learn the compact distribution of normal samples and detect outliers as anomalies in testing. Meanwhile, the anomalies in real-world are usually subtle and fine-grained in a…

Computer Vision and Pattern Recognition · Computer Science 2022-07-20 Ye Zheng , Xiang Wang , Rui Deng , Tianpeng Bao , Rui Zhao , Liwei Wu

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Conventional unsupervised anomaly detection (UAD) methods build separate models for each object category. Recent studies have proposed to train a unified model for multiple classes, namely model-unified UAD. However, such methods still…

Computer Vision and Pattern Recognition · Computer Science 2024-04-17 Jia Guo , Haonan Han , Shuai Lu , Weihang Zhang , Huiqi Li

Unsupervised anomaly detection in medical imaging aims to detect and localize arbitrary anomalies without requiring annotated anomalous data during training. Often, this is achieved by learning a data distribution of normal samples and…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Carsten T. Lüth , David Zimmerer , Gregor Koehler , Paul F. Jaeger , Fabian Isensee , Jens Petersen , Klaus H. Maier-Hein

Anomaly detection in medical imaging is a challenging task in contexts where abnormalities are not annotated. This problem can be addressed through unsupervised anomaly detection (UAD) methods, which identify features that do not match with…

Image and Video Processing · Electrical Eng. & Systems 2023-09-07 Geoffroy Oudoumanessah , Carole Lartizien , Michel Dojat , Florence Forbes

The core challenge in unsupervised anomaly detection is identifying abnormal patterns without prior knowledge of their characteristics. While existing methods have addressed aspects of this problem, they often struggle to learn a robust…

Machine Learning · Computer Science 2026-05-12 Prithul Sarker , Sushmita Sarker , Nicholas G. Murray , Alireza Tavakkoli

Unsupervised anomaly detection (UAD) aims to identify image- and pixel-level anomalies using only normal training data, with wide applications such as industrial inspection and medical analysis, where anomalies are scarce due to privacy…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Zhe Zhang , Mingxiu Cai , Gaochang Wu , Jing Zhang , Lingqiao Liu , Dacheng Tao , Tianyou Chai , Xiatian Zhu

Unsupervised Anomaly Detection (UAD) plays a crucial role in identifying abnormal patterns within data without labeled examples, holding significant practical implications across various domains. Although the individual contributions of…

Machine Learning · Computer Science 2024-06-04 Zeyu Fang , Ming Gu , Sheng Zhou , Jiawei Chen , Qiaoyu Tan , Haishuai Wang , Jiajun Bu

Unsupervised anomaly detection (UAD) has been widely implemented in industrial and medical applications, which reduces the cost of manual annotation and improves efficiency in disease diagnosis. Recently, deep auto-encoder with its variants…

Computer Vision and Pattern Recognition · Computer Science 2023-03-31 Mingqing Wang , Jiawei Li , Zhenyang Li , Chengxiao Luo , Bin Chen , Shu-Tao Xia , Zhi Wang
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