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The training of medical image analysis systems using machine learning approaches follows a common script: collect and annotate a large dataset, train the classifier on the training set, and test it on a hold-out test set. This process bears…

Computer Vision and Pattern Recognition · Computer Science 2019-02-05 Gabriel Maicas , Andrew P. Bradley , Jacinto C. Nascimento , Ian Reid , Gustavo Carneiro

In medical image segmentation, limited external validity remains a critical obstacle when models are deployed across unseen datasets, an issue particularly pronounced in the ultrasound image domain. Existing solutions-such as domain…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Christian Schmidt , Heinrich Martin Overhoff

With the wide development of black-box machine learning algorithms, particularly deep neural network (DNN), the practical demand for the reliability assessment is rapidly rising. On the basis of the concept that `Bayesian deep learning…

Computer Vision and Pattern Recognition · Computer Science 2019-04-19 Kenta Hama , Takashi Matsubara , Kuniaki Uehara , Jianfei Cai

Screening mammograms is the gold standard for detecting breast cancer early. While a good amount of work has been performed on mammography image classification, especially with deep neural networks, there has not been much exploration into…

Machine Learning · Computer Science 2020-08-14 Anika Tabassum , Naimul Khan

We derive explicit non-asymptotic PAC-Bayes generalization bounds for Gibbs posteriors, that is, data-dependent distributions over model parameters obtained by exponentially tilting a prior with the empirical risk. Unlike classical…

Machine Learning · Statistics 2026-04-21 Chenyang Wang , Yun Yang

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira

Deep neural networks (DNNs) generalize remarkably well without explicit regularization even in the strongly over-parametrized regime where classical learning theory would instead predict that they would severely overfit. While many…

Machine Learning · Statistics 2019-04-23 Guillermo Valle-Pérez , Chico Q. Camargo , Ard A. Louis

Data augmentation is a widely used and effective technique to improve the generalization performance of deep neural networks. Yet, despite often facing limited data availability when working with medical images, it is frequently…

Image and Video Processing · Electrical Eng. & Systems 2025-07-21 Adam Tupper , Christian Gagné

Deep learning has demonstrated remarkable achievements in medical image segmentation. However, prevailing deep learning models struggle with poor generalization due to (i) intra-class variations, where the same class appears differently in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-09 Vandan Gorade , Sparsh Mittal , Debesh Jha , Rekha Singhal , Ulas Bagci

In active learning, the focus is mainly on the selection strategy of unlabeled data for enhancing the generalization capability of the next learning cycle. For this, various uncertainty measurement methods have been proposed. On the other…

Computer Vision and Pattern Recognition · Computer Science 2020-11-06 SeulGi Hong , Heonjin Ha , Junmo Kim , Min-Kook Choi

One of the principal scientific challenges in deep learning is explaining generalization, i.e., why the particular way the community now trains networks to achieve small training error also leads to small error on held-out data from the…

Symmetries are known to improve the empirical performance of machine learning models, yet theoretical guarantees explaining these gains remain limited. Prior work has focused mainly on compact group symmetries and often assumes that the…

Machine Learning · Computer Science 2025-10-21 Armin Beck , Peter Ochs

In this study, we automate quantitative mammographic breast density estimation with neural networks and show that this tool is a strong use case for federated learning on multi-institutional datasets. Our dataset included bilateral CC-view…

Meta learning automatically infers an inductive bias, that includes the hyperparameter of the base-learning algorithm, by observing data from a finite number of related tasks. This paper studies PAC-Bayes bounds on meta generalization gap.…

Machine Learning · Computer Science 2022-06-14 Arezou Rezazadeh

From the statistical learning perspective, complexity control via explicit regularization is a necessity for improving the generalization of over-parameterized models. However, the impressive generalization performance of neural networks…

Machine Learning · Computer Science 2021-02-09 Taejong Joo , Uijung Chung

We consider fine-tuning a pretrained deep neural network on a target task. We study the generalization properties of fine-tuning to understand the problem of overfitting, which has often been observed (e.g., when the target dataset is small…

Machine Learning · Computer Science 2023-12-27 Haotian Ju , Dongyue Li , Hongyang R. Zhang

The development of mobile and on the edge applications that embed deep convolutional neural models has the potential to revolutionise biomedicine. However, most deep learning models require computational resources that are not available in…

Computer Vision and Pattern Recognition · Computer Science 2022-05-20 Adrián Inés , Andrés Díaz-Pinto , César Domínguez , Jónathan Heras , Eloy Mata , Vico Pascual

Mammography, an X-ray-based imaging technique, remains central to the early detection of breast cancer. Recent advances in artificial intelligence have enabled increasingly sophisticated computer-aided diagnostic methods, evolving from…

Image and Video Processing · Electrical Eng. & Systems 2025-10-09 Daniel G. P. Petrini , Hae Yong Kim

Breast density is an important risk factor for breast cancer that also affects the specificity and sensitivity of screening mammography. Current federal legislation mandates reporting of breast density for all women undergoing breast…

Saliency maps have become a widely used method to make deep learning models more interpretable by providing post-hoc explanations of classifiers through identification of the most pertinent areas of the input medical image. They are…