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Many vertebrate motor and sensory systems decussate, or cross the midline to the opposite side of the body. The successful crossing of millions of axons during development requires a complex of tightly controlled regulatory processes.…

Neurons and Cognition · Quantitative Biology 2024-05-14 Troy Shinbrot , Wise Young

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

Neurons and Cognition · Quantitative Biology 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

Reverberating dynamics of neural network is modelled on PC in order to illustrate possible role of inhibition as binding controller in the network. The network is composed of binding neurons. In the binding neuron model the degree of…

Neurons and Cognition · Quantitative Biology 2013-05-17 Alexander Vidybida

Living systems, from single cells to higher vertebrates, receive a continuous stream of non-stationary inputs that they sense, e.g., via cell surface receptors or sensory organs. Integrating these time-varying, multi-sensory, and often…

Other Quantitative Biology · Quantitative Biology 2024-04-17 Daniel Koch , Akhilesh Nandan , Gayathri Ramesan , Aneta Koseska

Deep convolutional neural networks are generally regarded as robust function approximators. So far, this intuition is based on perturbations to external stimuli such as the images to be classified. Here we explore the robustness of…

Machine Learning · Computer Science 2017-03-27 Nicholas Cheney , Martin Schrimpf , Gabriel Kreiman

Most deep learning models are limited to specific datasets or tasks because of network structures using fixed layers. In this paper, we discuss the differences between existing neural networks and real human neurons, propose association…

Artificial Intelligence · Computer Science 2023-01-31 Seokjun Kim , Jaeeun Jang , Hyeoncheol Kim

The learning dynamics of biological brains and artificial neural networks are of interest to both neuroscience and machine learning. A key difference between them is that neural networks are often trained from a randomly initialized state…

Neural and Evolutionary Computing · Computer Science 2025-05-19 Benjamin Midler , Alejandro Pan Vazquez

Learning and memory may rely on the ability of neuronal circuits to reorganize by dendritic spine remodeling. We have looked for geometrical parameters of cortical circuits, which maximize information storage capacity associated with this…

Biological Physics · Physics 2007-05-23 Armen Stepanyants

The electric activities of cortical pyramidal neurons are supported by structurally stable, morphologically complex axo-dendritic trees. Anatomical differences between axons and dendrites in regard to their length or caliber reflect the…

Neurons and Cognition · Quantitative Biology 2020-09-23 Danko D. Georgiev , Stefan K. Kolev , Eliahu Cohen , James F. Glazebrook

Deep neural networks (DNNs) are known for extracting useful information from large amounts of data. However, the representations learned in DNNs are typically hard to interpret, especially in dense layers. One crucial issue of the classical…

Neural and Evolutionary Computing · Computer Science 2021-05-06 Yuyang Gao , Giorgio A. Ascoli , Liang Zhao

Neuronal circuits internally regulate electrical signaling via a host of homeostatic mechanisms. Two prominent mechanisms, synaptic scaling and structural plasticity, are believed to maintain average activity within an operating range by…

Neurons and Cognition · Quantitative Biology 2021-04-07 Saeed Aljaberi , Timothy O'Leary , Fulvio Forni

Neurons, as eukaryotic cells, have powerful internal computation capabilities. One neuron can have many distinct states, and brains can use this capability. Processes of neuron growth and maintenance use chemical signalling between cell…

Neurons and Cognition · Quantitative Biology 2025-12-10 Robert Worden

Why do biological and artificial neurons sometimes modularise, each encoding a single meaningful variable, and sometimes entangle their representation of many variables? In this work, we develop a theory of when biologically inspired…

Neurons and Cognition · Quantitative Biology 2025-08-05 Will Dorrell , Kyle Hsu , Luke Hollingsworth , Jin Hwa Lee , Jiajun Wu , Chelsea Finn , Peter E Latham , Tim EJ Behrens , James CR Whittington

In many normative theories of synaptic plasticity, weight updates implicitly depend on the chosen parametrization of the weights. This problem relates, for example, to neuronal morphology: synapses which are functionally equivalent in terms…

Neurons and Cognition · Quantitative Biology 2022-02-25 Elena Kreutzer , Walter M. Senn , Mihai A. Petrovici

Representation learning is the foundation for the recent success of neural network models. However, the distributed representations generated by neural networks are far from ideal. Due to their highly entangled nature, they are di cult to…

Machine Learning · Computer Science 2016-02-09 William Whitney

Neuroscience has long informed the development of artificial neural networks, but the success of modern architectures invites, in turn, the converse: can modern networks teach us lessons about brain function? Here, we examine the structure…

Neurons and Cognition · Quantitative Biology 2026-03-17 Peter Koenig , Mario Negrello

We analyze algorithmic and computational aspects of biological phenomena, such as replication and programmed death, in the context of machine learning. We use two different measures of neuron efficiency to develop machine learning…

Neural and Evolutionary Computing · Computer Science 2022-07-12 Andrey Grabovsky , Vitaly Vanchurin

Despite the latest prevailing success of deep neural networks (DNNs), several concerns have been raised against their usage, including the lack of intepretability the gap between DNNs and other well-established machine learning models, and…

Machine Learning · Computer Science 2021-01-01 Jianghao Shen , Sicheng Wang , Zhangyang Wang

Deep convolutional neural networks (CNN) brought revolution without any doubt to various challenging tasks, mainly in computer vision. However, their model designing still requires attention to reduce number of learnable parameters, with no…

Computer Vision and Pattern Recognition · Computer Science 2016-08-16 Ihsan Ullah , Alfredo Petrosino

Two different types of directed networks are investigated, transcriptional regulation networks and neural networks. The directed network structure are studied and also shown to reflect the different processes taking place on the networks.…

Disordered Systems and Neural Networks · Physics 2016-08-16 Andreas Grönlund