Related papers: Simulation study of Q statistic with constant weig…
Cochran's $Q$ statistic is routinely used for testing heterogeneity in meta-analysis. Its expected value (under an incorrect null distribution) is part of several popular estimators of the between-study variance, $\tau^2$. Those…
A variety of problems in random-effects meta-analysis arise from the conventional $Q$ statistic, which uses estimated inverse-variance (IV) weights. In previous work on standardized mean difference and log-odds-ratio, we found superior…
A number of popular estimators of the between-study variance, $\tau^2$, are based on the Cochran's $Q$ statistic for testing heterogeneity in meta analysis. We introduce new point and interval estimators of $\tau^2$ for log-odds-ratio.…
Meta-analysis seeks to combine the results of several experiments in order to improve the accuracy of decisions. It is common to use a test for homogeneity to determine if the results of the several experiments are sufficiently similar to…
When the individual studies assembled for a meta-analysis report means ($\mu_C$, $\mu_T$) for their treatment (T) and control (C) arms, but those data are on different scales or come from different instruments, the customary measure of…
Methods for random-effects meta-analysis require an estimate of the between-study variance, $\tau^2$. The performance of estimators of $\tau^2$ (measured by bias and coverage) affects their usefulness in assessing heterogeneity of…
Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is most commonly used. In this paper, we first illustrate with a simple example that the $I^2$ statistic is heavily…
We consider the setting of an aggregate data meta-analysis of a continuous outcome of interest. When the distribution of the outcome is skewed, it is often the case that some primary studies report the sample mean and standard deviation of…
Methods for random-effects meta-analysis require an estimate of the between-study variance, $\tau^2$. The performance of estimators of $\tau^2$ (measured by bias and coverage) affects their usefulness in assessing heterogeneity of…
Quantifying the heterogeneity is an important issue in meta-analysis, and among the existing measures, the $I^2$ statistic is the most commonly used measure in the literature. In this paper, we show that the $I^2$ statistic was, in fact,…
When conducting a meta-analysis of standardized mean differences (SMDs), it is common to assume equal variances in the two arms of each study. This leads to Cohen's $d$ estimates for which interpretation is simple. However, this simplicity…
Popular measures of meta-analysis heterogeneity, such as $I^2$, cannot be considered measures of population heterogeneity since they are dependant on samples sizes within studies. The coefficient of variation (CV) recently introduced and…
We consider a three-level meta-analysis of standardized mean differences. The standard method of estimation uses inverse-variance weights and REML/PL estimation of variance components for the random effects. We introduce new moment-based…
Random-effects meta-analysis requires an estimate of the between-study variance, $\tau^2$. We study methods of estimation of $\tau^2$ and its confidence interval in meta-analysis of odds ratio, and also the performance of related estimators…
The standardized mean difference (SMD) is a widely used measure of effect size, particularly common in psychology, clinical trials, and meta-analysis involving continuous outcomes. Traditionally, under the equal variance assumption, the SMD…
Given the limitations of using the Cox hazard ratio to summarize the magnitude of the treatment effect, alternative measures that do not have these limitations are gaining attention. One of the recently proposed alternative methods uses the…
Propensity score (PS) methods have been increasingly used in recent years when assessing treatment effects in nonrandomized studies. In terms of statistical methods, a number of new PS weighting methods were developed, and it was shown that…
As the most important tool to provide high-level evidence-based medicine, researchers can statistically summarize and combine data from multiple studies by conducting meta-analysis. In meta-analysis, mean differences are frequently used…
Meta-analysis combines pertinent information from existing studies to provide an overall estimate of population parameters/effect sizes, as well as to quantify and explain the differences between studies. However, testing the between-study…
Meta-regression is often used to form hypotheses about what is associated with heterogeneity in a meta-analysis and to estimate the extent to which effects can vary between cohorts and other distinguishing factors. However, study-level…