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Background. Studies have shown that the conventional left ventricular mechanical dyssynchrony (LVMD) parameters have their own statistical limitations. The purpose of this study is to extract new LVMD parameters from the phase analysis of…

Medical Physics · Physics 2023-12-22 Zhuo He , Xinwei Zhang , Chen Zhao , Zhiyong Qian , Yao Wang , Xiaofeng Hou , Jiangang Zou , Weihua Zhou

Diabetic retinopathy (DR) is a leading cause of blindness among diabetic patients. Deep learning models have shown promising results in automating the detection of DR. In the present work, we propose a new methodology that integrates a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Susmita Ghosh , Abhiroop Chatterjee

Deep Neural Networks - especially Convolutional Neural Network (ConvNet) has become the state-of-the-art for image classification, pattern recognition and various computer vision tasks. ConvNet has a huge potential in medical domain for…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Md Motiur Rahman Sagar , Martin Dyrba

Accurate assessment of myocardial tissue stiffness is pivotal for the diagnosis and prognosis of heart diseases. Left ventricular diastolic stiffness ($\beta$) obtained from the end-diastolic pressure-volume relationship (EDPVR) has…

Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…

Computer Vision and Pattern Recognition · Computer Science 2025-11-10 Yasemin Turkan , F. Boray Tek , M. Serdar Nazlı , Öykü Eren

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and delay progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical screening…

Machine Learning · Computer Science 2022-08-09 Yi Wang , Tianzi Wang , Zi Ye , Lingwei Meng , Shoukang Hu , Xixin Wu , Xunying Liu , Helen Meng

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

Computer Vision and Pattern Recognition · Computer Science 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

Medical Physics · Physics 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

In comparative studies of progressive diseases, such as randomized controlled trials (RCTs), the mean Change From Baseline (CFB) of a continuous outcome at a pre-specified follow-up time across subjects in the target population is a…

Methodology · Statistics 2024-11-15 Changyu Shen , Menglan Pang , Ling Zhu , Lu Tian

We present an operational component of a real-world patient triage system. Given a specific patient presentation, the system is able to assess the level of medical urgency and issue the most appropriate recommendation in terms of best point…

Computation and Language · Computer Science 2018-10-01 Ivan Girardi , Pengfei Ji , An-phi Nguyen , Nora Hollenstein , Adam Ivankay , Lorenz Kuhn , Chiara Marchiori , Ce Zhang

Medical vision-language models (Med-VLMs) have shown impressive results in tasks such as report generation and visual question answering, but they still face several limitations. Most notably, they underutilize patient metadata and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Fangqi Cheng , Surajit Ray , Xiaochen Yang

Deep learning has become an important tool for Alzheimer's disease (AD) classification from structural MRI. Many existing studies analyze individual 2D slices extracted from MRI volumes, while clinical neuroimaging practice typically relies…

Computer Vision and Pattern Recognition · Computer Science 2026-03-19 Md Sifat , Sania Akter , Akif Islam , Md. Ekramul Hamid , Abu Saleh Musa Miah , Najmul Hassan , Md Abdur Rahim , Jungpil Shin

For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

This study explores the potential of Rhythm Formant Analysis (RFA) to capture long-term temporal modulations in dementia speech. Specifically, we introduce RFA-derived rhythm spectrograms as novel features for dementia classification and…

Objective Automatic artery/vein (A/V) segmentation from fundus images is required to track blood vessel changes occurring with many pathologies including retinopathy and cardiovascular pathologies. One of the clinical measures that…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Fantin Girard , Conrad Kavalec , Farida Cheriet

Recent studies have confirmed cardiovascular diseases remain responsible for highest death toll amongst non-communicable diseases. Accurate left ventricular (LV) volume estimation is critical for valid diagnosis and management of various…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 F. Terhag , P. Knechtges , A. Basermann , R. Tempone

Objective: This work evaluates a new approach for calculating the left-ventricular (LV) early filling propagation velocity (VP) from color M-Mode (CMM) echocardiograms using wavelet analysis. Unlike current approaches, the method requires…

Medical Physics · Physics 2019-10-29 Sreyashi Chakraborty , Hiroyuki Iwano , Michael E. Hall , Pavlos P. Vlachos

Alzheimer's disease (AD) is a major neurodegenerative condition that affects millions around the world. As one of the main biomarkers in the AD diagnosis procedure, brain amyloid positivity is typically identified by positron emission…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Yanxi Chen , Mohammad Farazi , Zhangsihao Yang , Yonghui Fan , Nicholas Ashton , Eric M Reiman , Yi Su , Yalin Wang

Alzheimer's disease (AD), characterized by progressive cognitive decline and memory loss, presents a formidable global health challenge, underscoring the critical importance of early and precise diagnosis for timely interventions and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Arindam Majee , Avisek Gupta , Sourav Raha , Swagatam Das