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In the rapidly evolving field of bioimaging, the integration and orchestration of Findable, Accessible, Interoperable, and Reusable (FAIR) image analysis workflows remains a challenge. We introduce BIOMERO, a bridge connecting OMERO, a…

Software Engineering · Computer Science 2024-07-26 Torec T. Luik , Rodrigo Rosas-Bertolini , Eric A. J. Reits , Ron A. Hoebe , Przemek M. Krawczyk

The FAIR Principles are a set of good practices to improve the reproducibility and quality of data in an Open Science context. Different sets of indicators have been proposed to evaluate the FAIRness of digital objects, including datasets…

Digital Libraries · Computer Science 2023-06-28 Fernando Aguilar Gómez , Isabel Bernal

In the interdisciplinary field of microscopy research, managing and integrating large volumes of data stored across disparate platforms remains a major challenge. Data types such as bioimages, experimental records, and spectral information…

Computational Engineering, Finance, and Science · Computer Science 2025-08-29 Rodrigo Escobar Díaz Guerrero , Jamile Mohammad Jafari , Tobias Meyer-Zedler , Michael Schmitt , Juergen Popp , Thomas Bocklitz

The application of microscopy in biomedical research has come a long way since Antonie van Leeuwenhoek discovered unicellular organisms. Countless innovations have positioned light microscopy as a cornerstone of modern biology and a method…

According to the FAIR (findability, accessibility, interoperability, and reusability) principles, scientific data should always be stored with machine-readable descriptive metadata. Existing solutions to store data with metadata, such as…

Databases · Computer Science 2024-09-12 Albert K. Engstfeld , Johannes M. Hermann , Nicolas G. Hörmann , Julian Rüth

Research methods and procedures are core aspects of the research process. Metadata focused on these components is critical to supporting the FAIR principles, particularly reproducibility. The research reported on in this paper presents a…

It is challenging to determine whether datasets are findable, accessible, interoperable, and reusable (FAIR) because the FAIR Guiding Principles refer to highly idiosyncratic criteria regarding the metadata used to annotate datasets.…

Digital Libraries · Computer Science 2022-10-17 Mark A. Musen , Martin J. O'Connor , Erik Schultes , Marcos Martinez-Romero , Josef Hardi , John Graybeal

We present BIOMERO 2.0, a major evolution of the BIOMERO framework that transforms OMERO into a FAIR-compliant (findable, accessible, interoperable, and reusable), provenance-aware bioimaging platform. BIOMERO 2.0 integrates data import,…

Software Engineering · Computer Science 2026-05-27 Torec T. Luik , Joost de Folter , Rodrigo Rosas-Bertolini , Eric A. J. Reits , Ron A. Hoebe , Przemek M. Krawczyk

Scientists strive to make their datasets available in open repositories, with the goal that they be findable, accessible, interoperable, and reusable (FAIR). Although it is hard for most investigators to remember all the guiding principles…

Digital Libraries · Computer Science 2025-07-31 Mark A. Musen , Martin J. O'Connor , Josef Hardi , Marcos Martinez-Romero

The FAIR (Findable, Accessible, Interoperable, and Reusable) data principles [1] promote the interoperability of scientific data by encouraging the use of persistent identifiers, standardized vocabularies, and formal metadata structures.…

A large number of services for research data management strive to adhere to the FAIR guiding principles for scientific data management and stewardship. To evaluate these services and to indicate possible improvements, use-case-centric…

Computers and Society · Computer Science 2019-02-01 Tobias Weber , Dieter Kranzlmüller

Scientific data management is at a critical juncture, driven by exponential data growth, increasing cross-domain dependencies, and a severe reproducibility crisis in modern research. Traditional centralized data management approaches are…

Databases · Computer Science 2025-04-30 Sebastian Beyvers , Jannis Hochmuth , Lukas Brehm , Maria Hansen , Alexander Goesmann , Frank Förster

Metadata, often termed "data about data," is crucial for organizing, understanding, and managing vast omics datasets. It aids in efficient data discovery, integration, and interpretation, enabling users to access, comprehend, and utilize…

The FAIR principles are globally accepted guidelines for improved data management practices with the potential to align data spaces on a global scale. In practice, this is only marginally achieved through the different ways in which…

Databases · Computer Science 2025-05-15 Nicolas Blumenroehr , Philipp-Joachim Ost , Felix Kraus , Achim Streit

A multitude of work has shown that machine learning-based medical diagnosis systems can be biased against certain subgroups of people. This has motivated a growing number of bias mitigation algorithms that aim to address fairness issues in…

Machine Learning · Computer Science 2023-02-21 Yongshuo Zong , Yongxin Yang , Timothy Hospedales

Background: Biomedical research projects deal with data management requirements from multiple sources like funding agencies' guidelines, publisher policies, discipline best practices, and their own users' needs. We describe functional and…

Medical image classification plays a crucial role in computer-aided clinical diagnosis. While deep learning techniques have significantly enhanced efficiency and reduced costs, the privacy-sensitive nature of medical imaging data…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Sufen Ren , Yule Hu , Shengchao Chen , Guanjun Wang

Metadata play a crucial role in adopting the FAIR principles for research software and enables findability and reusability. However, creating high-quality metadata can be resource-intensive for researchers and research software engineers.…

Software Engineering · Computer Science 2025-12-17 Stephan Ferenz , Aida Jafarbigloo , Oliver Werth , Astrid Nieße
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