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Significant progress has been made on the model development for simulating turbulent reacting flows. As a consequence, we are currently in a position where key-physical aspects of fairly complex combustion processes are well understood at a…

Fluid Dynamics · Physics 2020-12-17 Matthias Ihme

Molecular property prediction is a crucial task that guides the design of new compounds, including drugs and materials. While explainable artificial intelligence methods aim to scrutinize model predictions by identifying influential…

Machine Learning · Computer Science 2025-08-27 Łukasz Janisiów , Marek Kochańczyk , Bartosz Zieliński , Tomasz Danel

In most of the cases, the experimental study of Nanotechnology involves high cost for Laboratory set-up and the experimentation processes were also slow. So, one cannot rely on experimental nanotechnology alone. As such, the Computer-Based…

Emerging Technologies · Computer Science 2011-09-09 Tamal Sarkar , Samir Chandra Das , Ardhendu Mandal

Model-based process simulation can be used to derive designs and operating conditions of chemical processes that optimally balance multiple objectives, such as quality, costs, or environmental impacts. This work focuses on identifying…

Machine learning techniques are now routinely encountered in research laboratories across the globe. Impressive progress has been made through ML and AI techniques with regards to large data set processing. This progress has increased the…

Machine Learning · Computer Science 2026-02-27 Ilya Balabin , Thomas M. Kaiser

We present a perspective on molecular machine learning (ML) in the field of chemical process engineering. Recently, molecular ML has demonstrated great potential in (i) providing highly accurate predictions for properties of pure components…

Chemical Physics · Physics 2025-09-01 Jan G. Rittig , Manuel Dahmen , Martin Grohe , Philippe Schwaller , Alexander Mitsos

The first step in the construction of a regression model or a data-driven analysis, aiming to predict or elucidate the relationship between the atomic scale structure of matter and its properties, involves transforming the Cartesian…

Recent applications of machine learning (ML) reveal a noticeable shift from its use for predictive modeling in the sense of a data-driven construction of models mainly used for the purpose of prediction (of ground-truth facts) to its use…

Machine Learning · Computer Science 2021-12-16 Eyke Hüllermeier

Recently supervised machine learning has been ascending in providing new predictive approaches for chemical, biological and materials sciences applications. In this Perspective we focus on the interplay of machine learning algorithm with…

Computational models are an essential tool for the design, characterization, and discovery of novel materials. Hard computational tasks in materials science stretch the limits of existing high-performance supercomputing centers, consuming…

Quantum Physics · Physics 2024-09-20 Yuri Alexeev , Maximilian Amsler , Paul Baity , Marco Antonio Barroca , Sanzio Bassini , Torey Battelle , Daan Camps , David Casanova , Young Jai Choi , Frederic T. Chong , Charles Chung , Chris Codella , Antonio D. Corcoles , James Cruise , Alberto Di Meglio , Jonathan Dubois , Ivan Duran , Thomas Eckl , Sophia Economou , Stephan Eidenbenz , Bruce Elmegreen , Clyde Fare , Ismael Faro , Cristina Sanz Fernández , Rodrigo Neumann Barros Ferreira , Keisuke Fuji , Bryce Fuller , Laura Gagliardi , Giulia Galli , Jennifer R. Glick , Isacco Gobbi , Pranav Gokhale , Salvador de la Puente Gonzalez , Johannes Greiner , Bill Gropp , Michele Grossi , Emanuel Gull , Burns Healy , Benchen Huang , Travis S. Humble , Nobuyasu Ito , Artur F. Izmaylov , Ali Javadi-Abhari , Douglas Jennewein , Shantenu Jha , Liang Jiang , Barbara Jones , Wibe Albert de Jong , Petar Jurcevic , William Kirby , Stefan Kister , Masahiro Kitagawa , Joel Klassen , Katherine Klymko , Kwangwon Koh , Masaaki Kondo , Doga Murat Kurkcuoglu , Krzysztof Kurowski , Teodoro Laino , Ryan Landfield , Matt Leininger , Vicente Leyton-Ortega , Ang Li , Meifeng Lin , Junyu Liu , Nicolas Lorente , Andre Luckow , Simon Martiel , Francisco Martin-Fernandez , Margaret Martonosi , Claire Marvinney , Arcesio Castaneda Medina , Dirk Merten , Antonio Mezzacapo , Kristel Michielsen , Abhishek Mitra , Tushar Mittal , Kyungsun Moon , Joel Moore , Mario Motta , Young-Hye Na , Yunseong Nam , Prineha Narang , Yu-ya Ohnishi , Daniele Ottaviani , Matthew Otten , Scott Pakin , Vincent R. Pascuzzi , Ed Penault , Tomasz Piontek , Jed Pitera , Patrick Rall , Gokul Subramanian Ravi , Niall Robertson , Matteo Rossi , Piotr Rydlichowski , Hoon Ryu , Georgy Samsonidze , Mitsuhisa Sato , Nishant Saurabh , Vidushi Sharma , Kunal Sharma , Soyoung Shin , George Slessman , Mathias Steiner , Iskandar Sitdikov , In-Saeng Suh , Eric Switzer , Wei Tang , Joel Thompson , Synge Todo , Minh Tran , Dimitar Trenev , Christian Trott , Huan-Hsin Tseng , Esin Tureci , David García Valinas , Sofia Vallecorsa , Christopher Wever , Konrad Wojciechowski , Xiaodi Wu , Shinjae Yoo , Nobuyuki Yoshioka , Victor Wen-zhe Yu , Seiji Yunoki , Sergiy Zhuk , Dmitry Zubarev

Key questions that scientists and engineers typically want to address can be formulated in terms of predictive science. Questions such as: "How well does my computational model represent reality?", "What are the most important parameters in…

Mathematical Software · Computer Science 2012-02-07 Michael M. McKerns , Leif Strand , Tim Sullivan , Alta Fang , Michael A. G. Aivazis

Simulations play a crucial role in the modern scientific process. Yet despite (or due to) this ubiquity, the Data Science community shares neither a comprehensive definition for a "high-quality" study nor a consolidated guide to designing…

Computation · Statistics 2025-05-16 Corrine F Elliott , James PC Duncan , Tiffany M Tang , Merle Behr , Karl Kumbier , Bin Yu

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

Quality control in industrial processes is increasingly making use of prior scientific knowledge, often encoded in physical models that require numerical approximation. Statistical prediction, and subsequent optimization, is key to ensuring…

Other Statistics · Statistics 2018-10-23 Antony Overstall , David Woods , Kieran Martin

Predicting the chemical properties of compounds is crucial in discovering novel materials and drugs with specific desired characteristics. Recent significant advances in machine learning technologies have enabled automatic predictive…

Quantitative Methods · Quantitative Biology 2021-12-10 Yang Liu , Hisashi Kashima

Predicting whether a molecule can cross the blood-brain barrier (BBB) is a key step in early-stage neuro-pharmaceutical design, directly influencing the efficiency and success rate of drug development. Traditional methods based on…

Quantitative Methods · Quantitative Biology 2026-03-16 Zihan Yang , Yuchen Xiao

Data science has the potential to improve business in a variety of verticals. While the lion's share of data science projects uses a predictive approach, to drive improvements these predictions should become decisions. However, such a…

Machine Learning · Computer Science 2022-06-22 Hanan Shteingart , Gerben Oostra , Ohad Levinkron , Naama Parush , Gil Shabat , Daniel Aronovich

The subject of this work is quantum predicative programming -- the study of developing of programs intended for execution on a quantum computer. We look at programming in the context of formal methods of program development, or programming…

Quantum Physics · Physics 2008-02-19 Anya Tafliovich , E. C. R. Hehner

For decades, computational chemistry has been posited as one of the areas in which quantum computing would revolutionize. However, the algorithmic advantages that fault-tolerant quantum computers have for chemistry can be overwhelmed by…

Molecular dynamics simulation is now a widespread approach for understanding complex systems on the atomistic scale. It finds applications from physics and chemistry to engineering, life and medical science. In the last decade, the approach…

Computational Physics · Physics 2021-04-28 Shunzhou Wan , Robert C. Sinclair , Peter V. Coveney