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Translocation of a daughter vesicle from a mother vesicle through a pore is experimentally studied by many groups using a model system of self-reproducing vesicles. However, the theoretical formulation of the problem is not fully…

Soft Condensed Matter · Physics 2023-11-14 Manit Klawtanong , Yuka Sakuma , Masayuki Imai , Toshihiro Kawakatsu , Petch Khunpetch

This paper describes a 2D particle system in which autopoietic vesicles that are able to grow, repair, and reproduce can emerge from an initial random distribution of individual components. The reproduction process also exhibits inheritance…

Biological Physics · Physics 2024-07-23 Thomas Cabaret

The reproduction of a living cell requires a repeatable set of chemical events to be properly coordinated. Such events define a replication cycle, coupling the growth and shape change of the cell membrane with internal metabolic reactions.…

Cell Behavior · Quantitative Biology 2007-05-23 J. Macia , R. V. Sole

Cellular life requires the presence of a set of biochemical mechanisms in order to maintain a predictable process of growth and division. Several attempts have been made towards the building of minimal protocells from a top-down approach,…

Cell Behavior · Quantitative Biology 2007-05-23 Javier Macia , Ricard V. Sole

Cilia and flagella are actively bending slender organelles, performing functions such as motility, feeding and embryonic symmetry breaking. We review the mechanics of viscous-dominated microscale flow, including time-reversal symmetry, drag…

Quantitative Methods · Quantitative Biology 2013-09-06 Thomas D. Montenegro-Johnson , Andrew A. Smith , David J. Smith , Daniel Loghin , John R. Blake

Individual-based models of chemical or biological dynamics usually consider individual entities diffusing in space and performing a birth-death type dynamics. In this work we study the properties of a model in this class where the birth…

Statistical Mechanics · Physics 2009-11-11 Emilio Hernandez-Garcia , Cristobal Lopez

Transport of microscopic objects across biological membranes usually involves membrane deformation to enclose the object followed by detachment of the engulfed particle. However, in artificial membranes, this last topological remodelling…

Soft Condensed Matter · Physics 2025-03-25 Florent Fessler , Pierre Muller , Antonio Stocco

We propose a systematic formulation of the migration behaviors of a vesicle in a Poiseuille flow based on Onsager's variational principle. Our model is described by a combination of the phase field theory for the vesicle and the…

Soft Condensed Matter · Physics 2014-11-03 Yutaka Oya , Toshihiro Kawakatsu

Using a microfluidic trap, we study the behavior of individual phospholipid vesicles in contact with fatty acids. We show that spontaneous fatty acids insertion inside the bilayer is controlled by the vesicle size, osmotic pressure…

Subcellular Processes · Quantitative Biology 2016-12-14 Julien Dervaux , Vincent Noireaux , Albert Libchaber

The process of fission and vesicle formation depends on the geometry of the membrane that will split. For instance, a flat surface finds it difficult to form vesicles because of the lack of curved regions where to start the process. Here we…

Soft Condensed Matter · Physics 2023-03-21 Andreu F. Gallen , J. Roberto Romero-Arias , Rafael A. Barrio , Aurora Hernandez-Machado

We propose a free energy expression accounting for the formation of spherical vesicles from planar lipidic membranes and derive a Fokker-Planck equation for the probability distribution describing the dynamics of vesicle formation. We found…

Biological Physics · Physics 2015-05-13 E. Hernandez Zapata , L. Martinez Balbuena , I Santamaria-Holek

The newly developed "void expansion method" allows for an efficient generation of porous packings of spherical particles over a wide range of volume fractions using the discrete element method. Particles are randomly placed under addition…

Soft Condensed Matter · Physics 2009-11-09 Iwan Schenker , Frank T. Filser , Hans J. Herrmann , Ludwig J. Gauckler

The design of artificial microswimmers is often inspired by the strategies of natural microorganisms. Many of these creatures exploit the fact that elasticity breaks the time-reversal symmetry of motion at low Reynolds numbers, but this…

We analyze the free energy for translocation of a polymer from the outside of a spherical vesicle to the inside. The process is assumed to be driven by the adsorption of the polymer on the inner surface of the vesicle. We argue that in the…

Soft Condensed Matter · Physics 2009-10-31 K. Kiran Kumar , K. L. Sebastian

Osmotic deflation of vesicles enclosing two liquid phases can lead to bulging of one of the phases from the vesicle body. This budding process is preceded by a complete to partial wetting transition of one of the liquid phases on the…

Soft Condensed Matter · Physics 2012-01-17 Yanhong Li , Halim Kusumaatmaja , Reinhard Lipowsky , Rumiana Dimova

Micro droplets are extensively used in chemical, biological, and medical research, primarily for conducting various tests on samples, including living organisms, using a microfluidic framework. Recent studies have shown that the physiology…

Fluid Dynamics · Physics 2025-05-27 Siddhant Jain , Saini Jatin Rao , Shubhadeep Mandal , Cameron Tropea , Saptarshi Basu

Uncovering the rules governing the nonequilibrium dynamics of the membranes that define biological cells is of central importance to understanding the physics of living systems. We theoretically and computationally investigate the behavior…

We use coarse-grained molecular dynamics simulations to study the motility of a 2D vesicle containing self-propelled rods, as a function of the vesicle bending rigidity and the number density, length, and activity of the enclosed rods.…

Soft Condensed Matter · Physics 2023-03-29 Sarvesh Uplap , Michael F. Hagan , Aparna Baskaran

Vesicle budding induced by protein binding that generates an isotropic spontaneous curvature is studied using a mean-field theory. Many spherical buds are formed via protein binding. As the binding chemical potential increases, the proteins…

Soft Condensed Matter · Physics 2021-07-30 Hiroshi Noguchi

We investigate continuous generation of bubbles from a bath of air in viscous liquid in a confined geometry. In our original setup, bubbles are spontaneously generated by virtue of buoyancy and a gate placed in the cell: the gate acts like…

Fluid Dynamics · Physics 2025-06-17 Haruka Hitomi , Ko Okumura
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