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Inspired by the recent success of deep neural networks and the recent efforts to develop multi-layer dictionary models, we propose a Deep Analysis dictionary Model (DeepAM) which is optimized to address a specific regression task known as…

Machine Learning · Statistics 2021-02-03 Jun-Jie Huang , Pier Luigi Dragotti

An interpretable machine learning (ML) framework is introduced to enhance the diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) by ensuring robustness of the ML models' interpretations. The dataset used comprises…

Heterogeneity of brain diseases is a challenge for precision diagnosis/prognosis. We describe and validate Smile-GAN (SeMI-supervised cLustEring-Generative Adversarial Network), a novel semi-supervised deep-clustering method, which dissects…

Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive memory and cognitive decline, affecting millions worldwide. Diagnosing AD is challenging due to its heterogeneous nature and variable progression. This…

Neurons and Cognition · Quantitative Biology 2024-10-22 Jiwon Youn , Dong Woo Kang , Hyun Kook Lim , Mansu Kim

Automated methods for Alzheimer's disease (AD) classification have the potential for great clinical benefits and may provide insight for combating the disease. Machine learning, and more specifically deep neural networks, have been shown to…

The assessment of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) associated with brain changes remains a challenging task. Recent studies have demonstrated that combination of multi-modality imaging techniques can better…

Machine Learning · Computer Science 2022-09-26 Jun Yu , Zhaoming Kong , Liang Zhan , Li Shen , Lifang He

Current developments in computer vision and deep learning allow to automatically generate hyper-realistic images, hardly distinguishable from real ones. In particular, human face generation achieved a stunning level of realism, opening new…

Computer Vision and Pattern Recognition · Computer Science 2019-10-08 Francesco Marra , Cristiano Saltori , Giulia Boato , Luisa Verdoliva

We present variational generative adversarial networks, a general learning framework that combines a variational auto-encoder with a generative adversarial network, for synthesizing images in fine-grained categories, such as faces of a…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Jianmin Bao , Dong Chen , Fang Wen , Houqiang Li , Gang Hua

MRI-based brain age estimation models aim to assess a subject's biological brain age based on information, such as neuroanatomical features. Various factors, including neurodegenerative diseases, can accelerate brain aging and measuring…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Simon Joseph Clément Crête , Marta Kersten-Oertel , Yiming Xiao

Multiplex Imaging (MI) enables the simultaneous visualization of multiple biological markers in separate imaging channels at subcellular resolution, providing valuable insights into cell-type heterogeneity and spatial organization. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Simon Gutwein , Daria Lazic , Thomas Walter , Sabine Taschner-Mandl , Roxane Licandro

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Machine Learning · Computer Science 2016-07-05 Ehsan Hosseini-Asl , Georgy Gimel'farb , Ayman El-Baz

Deep learning models have shown promising performance for cell nucleus segmentation in the field of pathology image analysis. However, training a robust model from multiple domains remains a great challenge for cell nucleus segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Dawei Fan , Yifan Gao , Jiaming Yu , Yanping Chen , Wencheng Li , Chuancong Lin , Kaibin Li , Changcai Yang , Riqing Chen , Lifang Wei

Medical images used in clinical practice are heterogeneous and not the same quality as scans studied in academic research. Preprocessing breaks down in extreme cases when anatomy, artifacts, or imaging parameters are unusual or protocols…

Image and Video Processing · Electrical Eng. & Systems 2022-08-31 Mostafa Mehdipour Ghazi , Mads Nielsen

Localization of anatomical landmarks is essential for clinical diagnosis, treatment planning, and research. In this paper, we propose a novel deep network, named feature aggregation and refinement network (FARNet), for the automatic…

Computer Vision and Pattern Recognition · Computer Science 2021-11-02 Yueyuan Ao , Hong Wu

Accurate and early diagnosis of Alzheimer's disease (AD) is critical for effective intervention and requires integrating complementary information from multimodal neuroimaging data. However, conventional fusion approaches often rely on…

Machine Learning · Computer Science 2026-04-14 Farica Zhuang , Shu Yang , Dinara Aliyeva , Zixuan Wen , Duy Duong-Tran , Christos Davatzikos , Tianlong Chen , Song Wang , Li Shen

Segmentation quality assessment (SQA) plays a critical role in the deployment of a medical image based AI system. Users need to be informed/alerted whenever an AI system generates unreliable/incorrect predictions. With the introduction of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Yizhe Zhang , Shuo Wang , Tao Zhou , Qi Dou , Danny Z. Chen

Multi-modal neuroimaging technology has greatlly facilitated the efficiency and diagnosis accuracy, which provides complementary information in discovering objective disease biomarkers. Conventional deep learning methods, e.g. convolutional…

Image and Video Processing · Electrical Eng. & Systems 2022-10-26 Yanwu Yang , Xutao Guo , Zhikai Chang , Chenfei Ye , Yang Xiang , Ting Ma

No-reference image quality assessment (NR-IQA) aims to simulate the process of perceiving image quality aligned with subjective human perception. However, existing NR-IQA methods either focus on global representations that leads to limited…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Chenyue Song , Chen Hui , Haiqi Zhu , Feng Jiang , Yachun Mi , Wei Zhang , Shaohui Liu

Multi-domain image-to-image translation with conditional Generative Adversarial Networks (GANs) can generate highly photo realistic images with desired target classes, yet these synthetic images have not always been helpful to improve…

Computer Vision and Pattern Recognition · Computer Science 2021-05-13 Suman Sapkota , Bidur Khanal , Binod Bhattarai , Bishesh Khanal , Tae-Kyun Kim

Facial Attribute Classification (FAC) has attracted increasing attention in computer vision and pattern recognition. However, state-of-the-art FAC methods perform face detection/alignment and FAC independently. The inherent dependencies…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Longbiao Mao , Yan Yan , Jing-Hao Xue , Hanzi Wang