Related papers: Force spectroscopy with electromagnetic tweezers
The multislice method, which simulates the propagation of the incident electron wavefunction through a crystal, is a well-established method for analyzing the multiple scattering effects that an electron beam may undergo. The inclusion of…
Tethered particle motion experiments are versatile single-molecule techniques enabling one to address in vitro the molecular properties of DNA and its interactions with various partners involved in genetic regulations. These techniques…
The ability to create dynamic, tailored optical potentials has become important across fields ranging from biology to quantum science. We demonstrate a method for the creation of arbitrary optical tweezer potentials using the broadband…
We introduce a novel three-dimensional (3D) traction force microscopy (TFM) method motivated by the recent discovery that cells adhering on plane surfaces exert both in-plane and out-of-plane traction stresses. We measure the 3D deformation…
Experimental variables of optical tweezers instrumentation that affect RNA folding/unfolding kinetics were investigated. A model RNA hairpin, P5ab, was attached to two micron-sized beads through hybrid RNA/DNA handles; one bead was trapped…
Adherent cells exert traction forces on to their environment, which allows them to migrate, to maintain tissue integrity, and to form complex multicellular structures. This traction can be measured in a perturbation-free manner with…
Fully internal and motional state controlled and individually manipulable polar molecules are desirable for many quantum science applications leveraging the rich state space and intrinsic interactions of molecules. While prior efforts at…
When mixed together, DNA and polyaminoamide (PAMAM) dendrimers form fibers that condense into a compact structure. We use optical tweezers to pull condensed fibers and investigate the decondensation transition by measuring force-extension…
Changes in strain can be used to modify electronic and magnetic properties in crystal structures, to manipulate nanoparticles and cells, or to control chemical reactions. The magneto-elastic (ME) effect--the change of magnetic properties…
Optical tweezers, formed by tightly focused propagating laser beams, offer the unique capability to trap and control microscopic particles over a broad size range. However, the diffraction inherent to propagating optical fields, limits the…
We present an analytical and numerical study of electromagnetic modes in micro and nano fibers (MNFs) where the electric and magnetic fields of the modes are not necessarily orthogonal to each other. We first investigate these modes for…
Animal cells use traction forces to sense the mechanics and geometry of their environment. Measuring these traction forces requires a workflow combining cell experiments, image processing and force reconstruction based on elasticity theory.…
Near-field patterns of light provide a way to optically trap, deliver and sort single nanoscopic particles in a wide variety of applications in nanophotonics, microbiology and nanotechnology. Using rigorous electromagnetic theory, we…
We have evaluated the electromagnetic spectral function and its spectral properties by computing the one-loop photon polarization tensor in presence of magnetic field, particularly in a strong field approximation compared to the thermal…
We present a method of detecting sequence defects by supercoiling DNA with magnetic tweezers. The method is sensitive to a single mismatched base pair in a DNA sequence of several thousand base pairs. We systematically compare DNA molecules…
The tremendous progress in light scattering engineering made it feasible to develop optical tweezers allowing capture, hold, and controllable displacement of submicronsize particles and biological structures. However, the momentum…
Precise manipulation of single molecules has already led to remarkable insights in physics, chemistry, biology and medicine. However, widespread adoption of single-molecule techniques has been impeded by equipment cost and the laborious…
In recent years, plasmonic optical tweezers have been used to trap nanoparticles and study interactions with their environment. An unavoidable challenge is the plasmonic heating due to resonant excitation and the resulting temperature rise…
Piezoelectric quartz tuning forks have been employed as the force sensor in a dynamic mode scanning force microscope operating at temperatures down to 1.7 K at He-gas pressures of typically 5 mbar. An electrochemically etched tungsten tip…
Plasmonic antennas, leveraging localized surface plasmon resonance (LSPR), hold significant promise for efficiently trapping nanoscale particles at low power levels. However, their effectiveness is hindered by photothermal effects in…