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We present a phenomenological theory for the phase behavior of ternary mixtures of cholesterol and saturated and unsaturated lipids, one which describes both liquid and gel phases, and illuminates the mechanism of the behavior. In a binary…

Biological Physics · Physics 2008-06-05 Gregory Garbès Putzel , Michael Schick

Liquid-liquid phase separation is key to understanding aqueous two-phase systems (ATPS) arising throughout cell biology, medical science, and the pharmaceutical industry. Controlling the detailed morphology of phase-separating compound…

Soft Condensed Matter · Physics 2023-10-27 Eric W. Hester , Sean P. Carney , Vishwesh Shah , Alyssa Arnheim , Bena Patel , Dino Di Carlo , Andrea L. Bertozzi

In this paper, we use the cell dynamics method to study the dynamics of phase transformation when three phases exist. The system we study is a two-dimensional system. The system is able to achieve three phases coexistence, which for…

Materials Science · Physics 2009-11-11 M. Iwamatsu

Active constituents burn fuel to sustain individual motion, giving rise to collective effects that are not seen in systems at thermal equilibrium, such as phase separation with purely repulsive interactions. There is a great potential in…

Statistical Mechanics · Physics 2024-02-16 Luke K. Davis , Karel Proesmans , Étienne Fodor

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

A diffuse-interface model for microstructure with an arbitrary number of components and phases was developed from basic thermodynamic and kinetic principles and formalized within a variational framework. The model includes a composition…

Materials Science · Physics 2011-07-28 Daniel A. Cogswell , W. Craig Carter

We propose here a new mechanism of droplet coarsening in phase-separating fluid mixtures. In contrast to the conventional understanding that there are no interactions between droplets in the late stage of spinodal decomposition, we…

Soft Condensed Matter · Physics 2009-10-30 Hajime Tanaka

We study the model of a molecular switch comprised of a molecule with a soft vibrational degree of freedom coupled to metallic leads. In the presence of strong electron-ion interaction, different charge states of the molecule correspond to…

Mesoscale and Nanoscale Physics · Physics 2008-12-18 Fabio Pistolesi , Yaroslav M. Blanter , Ivar Martin

At low temperature a thermodynamic system undergoes a phase transition when a physical parameter passes through a singularity point of the free energy, corresponding to formation of a new order. At high temperature the thermal fluctuations…

Statistical Mechanics · Physics 2014-06-17 Bo-Bo Wei , Shao-Wen Chen , Hoi-Chun Po , Ren-Bao Liu

The existence and search for thermodynamic phase transitions is of unfading interest. In this paper, we present numerical evidence of dynamical phase transitions occurring in boundary driven systems with a constrained integrated current. It…

Statistical Mechanics · Physics 2017-03-29 Ohad Shpielberg , Yaroslav Don , Eric Akkermans

A recently introduced particle-based model for fluid dynamics with continuous velocities is generalized to model immiscible binary mixtures. Excluded volume interactions between the two components are modeled by stochastic multiparticle…

Soft Condensed Matter · Physics 2015-05-13 Erkan Tuzel , Guoai Pan , Thomas Ihle , Daniel M. Kroll

Liquid mixtures of many interacting components often exhibit numerous coexisting types of droplets. An exciting example is the cytosol of biological cells, where diverse droplets, called condensates, are essential for cellular function.…

Soft Condensed Matter · Physics 2025-05-28 Yicheng Qiang , Chengjie Luo , David Zwicker

The phase transition kinetics in three phase systems was investigated using the numerically efficient cell dynamics method. A phasefield model with a simple analytical free energy and single order parameter was used to study the kinetics…

Materials Science · Physics 2010-03-23 Masao Iwamatsu

As phenomena that necessarily emerge from the collective behavior of interacting particles, phase transitions continue to be difficult to predict using statistical thermodynamics. A recent proposal called the topological hypothesis suggests…

Statistical Mechanics · Physics 2023-06-08 O. B. Ericok , J. K. Mason

Non-reciprocal interactions are among the simplest mechanisms that drive a physical system out of thermal equilibrium, leading to novel phenomena such as oscillatory pattern formation. In this paper, we introduce a ternary phase separation…

Soft Condensed Matter · Physics 2025-12-09 Xiao Ma , Michael E. Cates

Biomolecular condensates provide distinct chemical environments, which control various cellular processes. The diffusive dynamics and chemical kinetics inside phase-separated condensates can be studied experimentally by fluorescently…

Subcellular Processes · Quantitative Biology 2025-03-26 Stefano Bo , Lars Hubatsch , Frank Jülicher

A one-dimensional reaction-diffusion model consisting of two species of particles and vacancies on a ring is introduced. The number of particles in one species is conserved while in the other species it can fluctuate because of creation and…

Statistical Mechanics · Physics 2009-11-13 F H Jafarpour , B Ghavami

Droplets are essential for spatially controlling biomolecules in cells. To work properly, cells need to control the emergence and morphology of droplets. On the one hand, driven chemical reactions can affect droplets profoundly. For…

Soft Condensed Matter · Physics 2024-03-14 Noah Ziethen , David Zwicker

We have investigated thermodynamic and dynamic properties as well as the dielectric constant of water-metha\-nol model mixtures in the entire range of composition by using constant pressure molecular dynamics simulations at ambient…

Soft Condensed Matter · Physics 2015-12-25 E. Galicia-Andrés , H. Dominguez , L. Pusztai , O. Pizio

The dynamics of phase transitions plays a crucial r\^ole in the so-called interface between high energy particle physics and cosmology. Many of the interesting results generated during the last fifteen years or so rely on simplified…

High Energy Physics - Phenomenology · Physics 2007-05-23 Marcelo Gleiser