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Dengue is a vector-borne viral disease increasing dramatically over the past years due to improvement in human mobility. The movement of host individuals between and within the patches are captured via a residence-time matrix. A system of…

Populations and Evolution · Quantitative Biology 2018-10-04 Wolfgang Bock , Yashika Jayathunga

We propose a stochastic SIR model, specified as a system of stochastic differential equations, to analyse the data of the Italian COVID-19 epidemic, taking also into account the under-detection of infected and recovered individuals in the…

Populations and Evolution · Quantitative Biology 2021-02-22 Sara Pasquali , Antonio Pievatolo , Antonella Bodini , Fabrizio Ruggeri

The growing literature on the propagation of COVID-19 relies on various dynamic SIR-type models (Susceptible-Infected-Recovered) which yield model-dependent results. For transparency and ease of comparing the results, we introduce a common…

Populations and Evolution · Quantitative Biology 2020-06-19 Christian Gourieroux , Joann Jasiak

Predicting Pandemic evolution involves complex modeling challenges, often requiring detailed discrete mathematics executed on large volumes of epidemiological data. Differential equations have the advantage of offering smooth, well-behaved…

Biological Physics · Physics 2023-02-28 Clara Bender , Abhimanyu Ghosh , Hamed Vakili , Preetam Ghosh , Avik W. Ghosh

Hybrid numerical-experimental testing is a standard approach for complex dynamical structures that are, on the one hand, not easy to model due to complexity and parameter uncertainty and, on the other hand, too expensive for full-scale…

Dynamical Systems · Mathematics 2020-03-24 Benjamin Unger

In this research, we study the propagation patterns of epidemic diseases such as the COVID-19 coronavirus, from a mathematical modeling perspective. The study is based on an extensions of the well-known susceptible-infected-recovered (SIR)…

Populations and Evolution · Quantitative Biology 2021-01-01 Reza Sameni

In this work we propose a novel space-dependent multiscale model for the spread of infectious diseases in a two-dimensional spatial context on realistic geographical scenarios. The model couples a system of kinetic transport equations…

Numerical Analysis · Mathematics 2020-12-21 Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott

Compartmental ordinary differential equation (ODE) models are used extensively in mathematical biology. When transit between compartments occurs at a constant rate, the well-known linear chain trick can be used to show that the ODE model is…

Dynamical Systems · Mathematics 2021-09-17 Tyler Cassidy

The long duration of the COVID-19 pandemic allowed for multiple bursts in the infection and death rates, the so-called epidemic waves. This complex behavior is no longer tractable by simple compartmental model and requires more…

Ordinary differential equations (ODEs) can provide mechanistic models of temporally local changes of processes, where parameters are often informed by external knowledge. While ODEs are popular in systems modeling, they are less established…

Methodology · Statistics 2025-07-10 Maren Hackenberg , Astrid Pechmann , Clemens Kreutz , Janbernd Kirschner , Harald Binder

Infectious diseases are a threat for human health with tremendous impact on our society at large. The recent COVID-19 pandemic, caused by the SARS-CoV-2, is the latest example of a highly infectious disease ravaging the world, since late…

Populations and Evolution · Quantitative Biology 2021-09-17 Giacomo Cacciapaglia , Corentin Cot , Michele Della Morte , Stefan Hohenegger , Francesco Sannino , Shahram Vatani

Simulating the time evolution of Partial Differential Equations (PDEs) of large-scale systems is crucial in many scientific and engineering domains such as fluid dynamics, weather forecasting and their inverse optimization problems.…

Machine Learning · Computer Science 2022-10-13 Tailin Wu , Takashi Maruyama , Jure Leskovec

In [Ecological Complexity 44 (2020) Art. 100885, DOI: 10.1016/j.ecocom.2020.100885] a continuous-time compartmental mathematical model for the spread of the Coronavirus disease 2019 (COVID-19) is presented with Portugal as case study, from…

Numerical Analysis · Mathematics 2021-11-24 Sandra Vaz , Delfim F. M. Torres

Data-driven methodologies are nowadays ubiquitous. Their rapid development and spread have led to applications even beyond the traditional fields of science. As far as dynamical systems and differential equations are concerned, neural…

Numerical Analysis · Mathematics 2025-12-05 Dimitri Breda , Xunbi A. Ji , Gábor Orosz , Muhammad Tanveer

Coronavirus outbreak is one of the most challenging pandemics for the entire human population of the planet Earth. Techniques such as the isolation of infected persons and maintaining social distancing are the only preventive measures…

Social and Information Networks · Computer Science 2020-09-01 Rahul Mishra , Hari Prabhat Gupta , Tanima Dutta

Since the outbreak of COVID-19, an astronomical number of publications on the pandemic dynamics appeared in the literature, of which many use the susceptible infected removed (SIR) and susceptible exposed infected removed (SEIR) models, or…

Machine Learning · Computer Science 2021-11-03 Hua-Liang Wei , S. A. Billings

Differential equations (DEs) are commonly used to describe dynamic systems evolving in one (ordinary differential equations or ODEs) or in more than one dimensions (partial differential equations or PDEs). In real data applications the…

Methodology · Statistics 2013-11-25 Gianluca Frasso , Jonathan Jaeger , Philippe Lambert

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

Analysis of PDEs · Mathematics 2025-11-11 Aesol Jeon , Ki-Ahm Lee

This technical report describes a dynamic causal model of the spread of coronavirus through a population. The model is based upon ensemble or population dynamics that generate outcomes, like new cases and deaths over time. The purpose of…

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