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In this paper, we propose a novel model to analyze serially correlated two-dimensional functional data observed sparsely and irregularly on a domain which may not be a rectangle. Our approach employs a mixed effects model that specifies the…

Methodology · Statistics 2024-04-02 Shirun Shen , Huiya Zhou , Kejun He , Lan Zhou

For functional data lying on an unknown nonlinear low-dimensional space, we study manifold learning and introduce the notions of manifold mean, manifold modes of functional variation and of functional manifold components. These constitute…

Statistics Theory · Mathematics 2012-05-29 Dong Chen , Hans-Georg Müller

Classical regression methods treat covariates as a vector and estimate a corresponding vector of regression coefficients. Modern applications in medical imaging generate covariates of more complex form such as multidimensional arrays…

Methodology · Statistics 2013-10-22 Hua Zhou , Lexin Li , Hongtu Zhu

In many image analysis problems, the contours of objects carry important statistical information about shape. Such contours are typically affected by deformation variables including scaling, translation, rotation, and reparametrization.…

Methodology · Statistics 2026-05-26 Issam-Ali Moindjié , Cédric Beaulac , Marie-Hélène Descary

We consider functional linear regression models where functional outcomes are associated with scalar predictors by coefficient functions with shape constraints, such as monotonicity and convexity, that apply to sub-domains of interest. To…

Methodology · Statistics 2025-05-09 Kyunghee Han , Yeonjoo Park , Soo-Young Kim

We report the development of a scalar quantization approach that helps build tables of decision and reconstruction levels for any probability density function (pdf). Several example pdf's are used for illustration: Uniform, Gaussian,…

Medical Physics · Physics 2016-09-08 C. Tannous

Radiomics involves the study of tumor images to identify quantitative markers explaining cancer heterogeneity. The predominant approach is to extract hundreds to thousands of image features, including histogram features comprised of…

Functional data analysis, which handles data arising from curves, surfaces, volumes, manifolds and beyond in a variety of scientific fields, is a rapidly developing area in modern statistics and data science in the recent decades. The…

Methodology · Statistics 2020-08-21 Xiaoke Zhang , Wu Xue , Qiyue Wang

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Classification is a core topic in functional data analysis. A large number of functional classifiers have been proposed in the literature, most of which are based on functional principal component analysis or functional regression. In…

Methodology · Statistics 2025-10-14 Ruoxu Tan , Yiming Zang

Canonical correlation analysis (CCA) is a powerful technique for discovering whether or not hidden sources are commonly present in two (or more) datasets. Its well-appreciated merits include dimensionality reduction, clustering,…

Machine Learning · Computer Science 2018-08-15 Jia Chen , Gang Wang , Yanning Shen , Georgios B. Giannakis

The problem of linking functional connectomics to behavior is extremely challenging due to the complex interactions between the two distinct, but related, data domains. We propose a coupled manifold optimization framework which projects…

Machine Learning · Computer Science 2020-07-07 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

In this paper linear canonical correlation analysis (LCCA) is generalized by applying a structured transform to the joint probability distribution of the considered pair of random vectors, i.e., a transformation of the joint probability…

Methodology · Statistics 2015-06-03 Koby Todros , Alfred O. Hero

Bayes spaces were initially designed to provide a geometric framework for the modeling and analysis of distributional data. It has recently come to light that this methodology can be exploited to provide an orthogonal decomposition of…

Statistics Theory · Mathematics 2022-06-29 Christian Genest , Karel Hron , Johanna G. Nešlehová

Particulate matter data now include various particle sizes, which often manifest as a collection of curves observed sequentially over time. When considering 51 distinct particle sizes, these curves form a high-dimensional functional time…

Methodology · Statistics 2025-10-03 Han Lin Shang , Israel Martinez Hernandez

We examine Deep Canonically Correlated LSTMs as a way to learn nonlinear transformations of variable length sequences and embed them into a correlated, fixed dimensional space. We use LSTMs to transform multi-view time-series data…

Machine Learning · Statistics 2018-01-17 Neil Mallinar , Corbin Rosset

We consider a multiscale approach based on immersed methods for the efficient computational modeling of tissues composed of an elastic matrix (in two or three-dimensions) and a thin vascular structure (treated as a co-dimension two…

Numerical Analysis · Mathematics 2021-11-18 Luca Heltai , Alfonso Caiazzo

To understand the biology of cancer, joint analysis of multiple data modalities, including imaging and genomics, is crucial. The involved nature of gene-microenvironment interactions necessitates the use of algorithms which treat both data…

Signal Processing · Electrical Eng. & Systems 2018-02-27 Vaishnavi Subramanian , Benjamin Chidester , Jian Ma , Minh N. Do

Shape analysis and compuational anatomy both make use of sophisticated tools from infinite-dimensional differential manifolds and Riemannian geometry on spaces of functions. While comprehensive references for the mathematical foundations…

Differential Geometry · Mathematics 2018-07-31 Martins Bruveris

In computer vision and medical imaging, the problem of matching structures finds numerous applications from automatic annotation to data reconstruction. The data however, while corresponding to the same anatomy, are often very different in…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Pierre-Louis Antonsanti , Joan Glaunès , Thomas Benseghir , Vincent Jugnon , Irène Kaltenmark