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Related papers: Practices for Engineering Trustworthy Machine Lear…

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Machine learning (ML) models show strong promise for new biomedical prediction tasks, but concerns about trustworthiness have hindered their clinical adoption. In particular, it is often unclear whether a model relies on true clinical cues…

Machine Learning · Computer Science 2026-01-13 Dushan N. Wadduwage , Dineth Jayakody , Leonidas Zimianitis

Quantifying uncertainties for machine learning (ML) models is a foundational challenge in modern data analysis. This challenge is compounded by at least two key aspects of the field: (a) inconsistent terminology surrounding uncertainty and…

Machine Learning · Computer Science 2025-06-04 Shubhendu Trivedi , Brian D. Nord

Forming a reliable judgement of a machine learning (ML) model's appropriateness for an application ecosystem is critical for its responsible use, and requires considering a broad range of factors including harms, benefits, and…

Machine Learning · Computer Science 2022-05-12 Ben Hutchinson , Negar Rostamzadeh , Christina Greer , Katherine Heller , Vinodkumar Prabhakaran

Data-driven modeling based on Machine Learning (ML) is becoming a central component of protein engineering workflows. This perspective presents the elements necessary to develop effective, reliable, and reproducible ML models, and a set of…

Biomolecules · Quantitative Biology 2025-07-11 Fabio Herrera-Rocha , David Medina-Ortiz , Fabian Mauz , Juergen Pleiss , Mehdi D. Davari

Trustworthy machine learning is driving a large number of ML community works in order to improve ML acceptance and adoption. The main aspect of trustworthy machine learning are the followings: fairness, uncertainty, robustness,…

Machine Learning · Computer Science 2022-07-08 Gregory Scafarto , Nicolas Posocco , Antoine Bonnefoy

The adaptation and use of Machine Learning (ML) in our daily lives has led to concerns in lack of transparency, privacy, reliability, among others. As a result, we are seeing research in niche areas such as interpretability, causality, bias…

Machine Learning · Computer Science 2024-06-04 Fahimeh Fakour , Ali Mosleh , Ramin Ramezani

The accelerated adoption of AI-based software demands precise development guidelines to guarantee reliability, scalability, and ethical compliance. MLOps (Machine Learning and Operations) guidelines have emerged as the principal reference…

Software Engineering · Computer Science 2024-08-05 Sergio Moreschi , David Hästbacka , Andrea Janes , Valentina Lenarduzzi , Davide Taibi

Machine learning (ML) has recently created many new success stories. Hence, there is a strong motivation to use ML technology in software-intensive systems, including safety-critical systems. This raises the issue of safety verification of…

Software Engineering · Computer Science 2020-07-01 Hermann Kaindl , Stefan Kramer

Many research fields are currently reckoning with issues of poor levels of reproducibility. Some label it a "crisis", and research employing or building Machine Learning (ML) models is no exception. Issues including lack of transparency,…

Software Engineering · Computer Science 2025-02-27 Harald Semmelrock , Tony Ross-Hellauer , Simone Kopeinik , Dieter Theiler , Armin Haberl , Stefan Thalmann , Dominik Kowald

The recent popularity of large language models (LLMs) has brought a significant impact to boundless fields, particularly through their open-ended ecosystem such as the APIs, open-sourced models, and plugins. However, with their widespread…

Machine Learning · Computer Science 2023-08-31 Wentao Ye , Mingfeng Ou , Tianyi Li , Yipeng chen , Xuetao Ma , Yifan Yanggong , Sai Wu , Jie Fu , Gang Chen , Haobo Wang , Junbo Zhao

[Context] Machine learning (ML)-enabled systems are present in our society, driving significant digital transformations. The dynamic nature of ML development, characterized by experimental cycles and rapid changes in data, poses challenges…

Software Engineering · Computer Science 2025-06-27 Lucas Romao , Hugo Villamizar , Romeu Oliveira , Silvio Alonso , Marcos Kalinowski

Machine learning (ML) provides powerful tools for predictive modeling. ML's popularity stems from the promise of sample-level prediction with applications across a variety of fields from physics and marketing to healthcare. However, if not…

Recently, machine and deep learning (ML/DL) algorithms have been increasingly adopted in many software systems. Due to their inductive nature, ensuring the quality of these systems remains a significant challenge for the research community.…

Software Engineering · Computer Science 2024-07-16 Moses Openja , Foutse Khomh , Armstrong Foundjem , Zhen Ming , Jiang , Mouna Abidi , Ahmed E. Hassan

Machine learning (ML) components are increasingly integrated into software products, yet their complexity and inherent uncertainty often lead to unintended and hazardous consequences, both for individuals and society at large. Despite these…

Software Engineering · Computer Science 2025-09-15 Yining Hong , Christopher S. Timperley , Christian Kästner

Machine learning (ML) systems are rapidly increasing in size, are acquiring new capabilities, and are increasingly deployed in high-stakes settings. As with other powerful technologies, safety for ML should be a leading research priority.…

Machine Learning · Computer Science 2022-06-20 Dan Hendrycks , Nicholas Carlini , John Schulman , Jacob Steinhardt

This systematic literature review examines the critical challenges and solutions related to scalability and maintainability in Machine Learning (ML) systems. As ML applications become increasingly complex and widespread across industries,…

Software Engineering · Computer Science 2025-04-16 Karthik Shivashankar , Ghadi S. Al Hajj , Antonio Martini

Machine learning (ML) empowers biomedical systems with the capability to optimize their performance through modeling of the available data extremely well, without using strong assumptions about the modeled system. Especially in nano-scale…

Context: Dynamic production environments make it challenging to maintain reliable machine learning (ML) systems. Runtime issues, such as changes in data patterns or operating contexts, that degrade model performance are a common occurrence…

Software Engineering · Computer Science 2025-09-19 Hira Naveed , Scott Barnett , Chetan Arora , John Grundy , Hourieh Khalajzadeh , Omar Haggag

In spite of machine learning's rapid growth, its engineering support is scattered in many forms, and tends to favor certain engineering stages, stakeholders, and evaluation preferences. We envision a capability-based framework, which uses…

Artificial Intelligence · Computer Science 2023-02-14 Chenyang Yang , Rachel Brower-Sinning , Grace A. Lewis , Christian Kästner , Tongshuang Wu

Machine learning (ML) systems are increasingly deployed in high-stakes domains where reliability is paramount. This thesis investigates how uncertainty estimation can enhance the safety and trustworthiness of ML, focusing on selective…

Machine Learning · Computer Science 2025-09-09 Stephan Rabanser