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We propose a novel approach to the statistical analysis of stochastic simulation models and, especially, agent-based models (ABMs). Our main goal is to provide fully automated, model-independent and tool-supported techniques and algorithms…

General Economics · Economics 2023-11-09 Andrea Vandin , Daniele Giachini , Francesco Lamperti , Francesca Chiaromonte

Agent-based models of disease transmission involve stochastic rules that specify how a number of individuals would infect one another, recover or be removed from the population. Common yet stringent assumptions stipulate interchangeability…

Computation · Statistics 2021-01-29 Nianqiao Ju , Jeremy Heng , Pierre E. Jacob

Automatic classification of active tuberculosis from chest X-ray images has the potential to save lives, especially in low- and mid-income countries where skilled human experts can be scarce. Given the lack of available labeled data to…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Özgür Acar Güler , Manuel Günther , André Anjos

Background: This study introduces a Vision-Language Model (VLM) leveraging SIGLIP and Gemma-3b architectures for automated acute tuberculosis (TB) screening. By integrating chest X-ray images and clinical notes, the model aims to enhance…

Large language model-driven multi-agent systems (LLM-MAS) excel at complex tasks, yet unreliable agents remain a key bottleneck to system-level reliability. Automatic failure attribution is therefore critical, but existing approaches, such…

Computation and Language · Computer Science 2026-05-19 Hezhe Qiao , Hanghang Tong , Ee-Peng Lim , Bing Liu , Guansong Pang

Agent-based models (ABMs) highlight the importance of simulation validation, such as qualitative face validation and quantitative empirical validation. In particular, we focused on quantitative validation by adjusting simulation input…

Artificial Intelligence · Computer Science 2022-03-08 Dongjun Kim , Tae-Sub Yun , Il-Chul Moon , Jang Won Bae

Drawing meaningful conclusions from inherently multimodal clinical data (including medical imaging) requires coordinating expertise across the clinical specialty, radiology, programming, and biostatistics. This fragmented process…

Multiagent Systems · Computer Science 2026-04-15 Lucas Stoffl , Benedikt Wiestler , Johannes C. Paetzold

Over the years, population-level tobacco control policies have considerably reduced smoking prevalence worldwide. However, the rate of decline of smoking prevalence is slowing down. Therefore, there is a need for models that capture the…

Physics and Society · Physics 2022-07-19 Adarsh Prabhakaran , Valerio Restocchi , Benjamin D. Goddard

Formal modelling of Multi-Agent Systems (MAS) is a challenging task due to high complexity, interaction, parallelism and continuous change of roles and organisation between agents. In this paper we record our research experience on formal…

Multiagent Systems · Computer Science 2010-08-20 Petros Kefalas , Ioanna Stamatopoulou

Tuberculosis (TB) is an airborne disease caused by the pathogen Mycobacterium tuberculosis. In 2023, according to the World Health Organization, it ''probably'' replaced COVID-19 as the leading cause of death from an infectious agent…

Populations and Evolution · Quantitative Biology 2026-04-29 James W. G. Doran , Cameron A. Smith , Christian A. Yates , Ruth Bowness

Tuberculosis (TB), an infectious bacterial disease, is a significant cause of death, especially in low-income countries, with an estimated ten million new cases reported globally in $2020$. While TB is treatable, non-adherence to the…

Random numbers are at the heart of every agent-based model (ABM) of health and disease. By representing each individual in a synthetic population, agent-based models enable detailed analysis of intervention impact and parameter sensitivity.…

Quantitative Methods · Quantitative Biology 2024-09-09 Daniel J. Klein , Romesh G. Abeysuriya , Robyn M. Stuart , Cliff C. Kerr

The evaluation of infectious disease processes on radiologic images is an important and challenging task in medical image analysis. Pulmonary infections can often be best imaged and evaluated through computed tomography (CT) scans, which…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 Ashia Lewis , Evanjelin Mahmoodi , Yuyue Zhou , Megan Coffee , Elena Sizikova

The practical utility of agent-based models in decision-making relies on their capacity to accurately replicate populations while seamlessly integrating real-world data streams. Yet, the incorporation of such data poses significant…

Multiagent Systems · Computer Science 2024-04-22 Ayush Chopra , Arnau Quera-Bofarull , Nurullah Giray-Kuru , Michael Wooldridge , Ramesh Raskar

Agent-based modeling (ABM) offers powerful insights into complex systems, but its practical utility has been limited by computational constraints and simplistic agent behaviors, especially when simulating large populations. Recent…

Multiagent Systems · Computer Science 2024-11-12 Ayush Chopra , Shashank Kumar , Nurullah Giray-Kuru , Ramesh Raskar , Arnau Quera-Bofarull

Emergency departments (ED) face challenges in patient care and resource management. We propose to explore optimization strategies in a realistic and flexible model and develop a hybrid Discrete Event Simulation (DES) and Agent-Based Model…

Artificial Intelligence · Computer Science 2026-05-14 Markus Wenzel , Tobias Strapatsas , Jessika Kress , Dorothea Sauer , Nele Gessler , Horst K. Hahn

This paper presents a verification-based methodology to validate the model of personalized health conditions. The model identifies the values that may result in unsafe, un-reachable, in-exhaustive, and overlapping states that otherwise…

Software Engineering · Computer Science 2022-07-26 Najma Taimoor , Semeen Rehman

There is little research concerning comparisons and combination of System Dynamics Simulation (SDS) and Agent Based Simulation (ABS). ABS is a paradigm used in many levels of abstraction, including those levels covered by SDS. We believe…

Computational Engineering, Finance, and Science · Computer Science 2013-05-30 Grazziela P. Figueredo , Uwe Aickelin

Cellular Agent-Based Models are commonly employed to describe a variety biological systems. Over the course of the past years, many modeling tools have emerged which solve particular research questions. In this short opinion piece, we argue…

Cell Behavior · Quantitative Biology 2025-11-18 Jonas Pleyer

Agent-based modeling is a computational dynamic modeling technique that may be less familiar to some readers. Agent-based modeling seeks to understand the behaviour of complex systems by situating agents in an environment and studying the…

Multiagent Systems · Computer Science 2023-04-19 G. Wade McDonald , Nathaniel D. Osgood