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Related papers: Towards the development of human immune-system-on-…

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Tumor organoid-on-a-chip platforms represent a cutting-edge fusion of patient-derived organoids with microfluidic technologies, offering unprecedented capabilities for personalized cancer research. These systems overcome limitations of…

Tissues and Organs · Quantitative Biology 2025-07-30 Keyvan Alavi

The use of artificial immune systems in intrusion detection is an appealing concept for two reasons. Firstly, the human immune system provides the human body with a high level of protection from invading pathogens, in a robust,…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Jungwon Kim , Peter J. Bentley , Uwe Aickelin , Julie Greensmith , Gianni Tedesco , Jamie Twycross

A new type of microfluidic system for biological cell manipulation, a CMOS/microfluidic hybrid, is demonstrated. The hybrid system starts with a custom-designed CMOS (complementary metal-oxide semiconductor) chip fabricated in a…

Quantitative Methods · Quantitative Biology 2007-05-23 Hakho Lee , Yong Liu , Donhee Ham , Robert M. Westervelt

The use of artificial immune systems in intrusion detection is an appealing concept for two reasons. Firstly, the human immune system provides the human body with a high level of protection from invading pathogens, in a robust,…

Cryptography and Security · Computer Science 2013-05-31 Uwe Aickelin , Julie Greensmith , Jamie Twycross

Understanding and modelling the complexity of the immune system is a challenge that is shared by the ImmunoComplexiT$^1$ thematic network from the RNSC. The immune system is a complex biological, adaptive, highly diversified, self-organized…

Quantitative Methods · Quantitative Biology 2020-08-27 Véronique Thomas-Vaslin

We argue that immune system is an adaptive complex system. It is shown that it has emergent properties. Its network structure is of the small world network type. The network is of the threshold type, which helps in avoiding autoimmunity. It…

Populations and Evolution · Quantitative Biology 2008-01-08 E. Ahmed , A. H. Hashish

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Artificial Intelligence · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

The immune system is a highly parallel and distributed intelligent system which has learning, memory, and associative capabilities. Artificial Immune System is an evolutionary paradigm inspired by the biological aspects of the immune system…

Cryptography and Security · Computer Science 2011-02-22 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self or non-self substances. It does this with the help of…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Uwe Aickelin , Dipankar Dasgupta , Feng Gu

Label-free detecting multiple analytes in a high-throughput fashion has been one of the long-sought goals in biosensing applications. Yet, for all-optical approaches, interfacing state-of-the-art label-free techniques with microfluidics…

Quantitative Methods · Quantitative Biology 2023-08-14 Alexia Stollmann , Jose Garcia-Guirado , Jae-Sang Hong , Hyungsoon Im , Hakho Lee , Jaime Ortega Arroyo , Romain Quidant

The immune system can be thought as a complex network of different interacting elements. A cellular automaton, defined in shape-space, was recently shown to exhibit self-regulation and complex behavior and is, therefore, a good candidate to…

Statistical Mechanics · Physics 2009-10-31 Rita Maria Zorzenon dos Santos , Americo T. Bernardes

Advances in molecular biology are enabling rapid and efficient analyses for effective intervention in domains such as biology research, infectious disease management, food safety, and biodefense. The emergence of microfluidics and…

Quantitative Methods · Quantitative Biology 2017-03-28 Harikrishnan Jayamohan , Valentin Romanov , Huizhong Li , Jiyoung Son , Raheel Samuel , John Nelson , Bruce Gale

The biological immune system is a robust, complex, adaptive system that defends the body from foreign pathogens. It is able to categorize all cells (or molecules) within the body as self-cells or non-self cells. It does this with the help…

Neural and Evolutionary Computing · Computer Science 2010-07-05 Uwe Aickelin , Dipankar Dasgupta

In this little vision paper we analyze the human immune system from a computer science point of view with the aim of understanding the architecture and features that allow robust, effective behavior to emerge from local sensing and actions.…

Computational Engineering, Finance, and Science · Computer Science 2013-09-23 Carolyn Talcott

Organoids offer a promising alternative in biomedical research and clinical medicine, with better feature recapitulation than 2D cultures. They also have more consistent responses with clinical results when compared to animal models.…

Tissues and Organs · Quantitative Biology 2025-10-15 Caroline Ferguson , Yan Li , Yi Zhang , Xueju Wang

A system architecture is suggested for a System on Chip that will combine several different memristor-based, bio-inspired computation arrays with inter- and intra-chip communication. It will serve as a benchmark system for future…

Emerging Technologies · Computer Science 2025-05-19 Christian Grewing , Arun Ashok , Sabitha Kusuma , Michael Schiek , Andre Zambanini , Stefan van Waasen

We investigate the microscopic contact of a cell/semiconductor hybrid. The semiconductor is nanostructured with the aim of single channel recording of ion channels in cell membranes. This approach will overcome many limitations of the…

Soft Condensed Matter · Physics 2007-05-23 N. Fertig , A. Tilke , R. H. Blick , J. P. Kotthaus , J. C. Behrends , G. ten Bruggencate

Nanophotonics has become a key enabling technology in biomedicine with great promises in early diagnosis and less invasive therapies. In this context, the unique capability of plasmonic noble metal nanoparticles to concentrate light on the…

Applied Physics · Physics 2017-08-02 Ozlem Yavas , Mikael Svedendahl , Paulina Dobosz , Vanesa Sanz , Romain Quidant

The immune system is a cognitive system of complexity comparable to the brain and its computational algorithms suggest new solutions to engineering problems or new ways of looking at these problems. Using immunological principles, a two (or…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 P. J. Costa Branco , J. A. Dente , R. Vilela Mendes

The human immune system has numerous properties that make it ripe for exploitation in the computational domain, such as robustness and fault tolerance, and many different algorithms, collectively termed Artificial Immune Systems (AIS), have…

Artificial Intelligence · Computer Science 2010-07-05 Julie Greensmith , Amanda Whitbrook , Uwe Aickelin
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