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Related papers: Intrinsic Dynamics of Protein-Peptide Unbinding

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We present evidence of ultrafast random lasing from the fluorescent protein DsRed2 embedded in a random one-dimensional cavity. Lasing is achieved when a purified protein solution, placed inside a layered random medium, is optically excited…

Optics · Physics 2015-02-16 T. M. Drane , H. Bach , M. Shapiro , V. Milner

We propose a novel approach to detect the binding between proteins making use of the anomalous diffraction of natively present heavy elements inside the molecule 3D structure. In particular, we suggest considering sulfur atoms contained in…

Hydrated proteins undergo a transition in the deeply supercooled regime, which is attributed to rapid changes in hydration water and protein structural dynamics. Here, we investigate the nanoscale stress relaxation in hydrated lysozyme…

A comprehensive photoluminescence and mechanoluminescence analysis of ZnS:Mn2+ nano-phosphor with zinc blende structure is presented. The sample containing quantum dot-sized nanocrystallites were synthesized by the chemical precipitation…

Protein dynamics form a critical bridge between protein structure and function, yet the impact of evolution on ultrafast processes inside proteins remains enigmatic. This study delves deep into nanosecond-scale protein dynamics of a…

Biological Physics · Physics 2023-09-13 Philipp J. Heckmeier , Jeannette Ruf , Charlotte Rochereau , Peter Hamm

One of the major functions of RecA protein in the cell is to bind single-stranded DNA exposed upon damage, thereby triggering the SOS repair response.We present fluorescence anisotropy measurements at the binding onset, showing enhanced DNA…

Biological Physics · Physics 2010-08-05 Tsvi Tlusty , Roy Bar-Ziv , Albert Libchaber

Employing the four-band tight-binding model we study theoretically the doping dependence of the spin response in the normal state of novel Fe-based pnictide superconductors. We show that the commensurate spin density wave (SDW) transition…

Superconductivity · Physics 2008-09-11 M. M. Korshunov , I. Eremin

Intrinsically disordered proteins participate in many biological processes by folding upon binding with other proteins. However, coupled folding and binding processes are not well understood from an atomistic point of view. One of the main…

Biomolecules · Quantitative Biology 2023-02-22 Pablo Herrera-Nieto , Adrià Pérez , Gianni De Fabritiis

Using femtosecond time-resolved x-ray diffraction we investigate the structural dynamics of the coherently excited A1g phonon mode in the Fe-pnictide parent compound BaFe2As2. The fluence dependent intensity oscillations of two specific…

Protein activation and deactivation is central to a variety of biological mechanisms, including cellular signaling and transport. Unimolecular fluorescent resonance energy transfer (FRET) probes are a class of fusion protein sensors that…

Biomolecules · Quantitative Biology 2018-11-30 Shourjya Sanyal , David F. Coker , Donal MacKernan

A self-consistent expression for the surface recombination velocity $S$ and the surface Fermi level unpinning energy as a function of light excitation power ($P$) is presented for n- and p-type semiconductors doped above the 10$^{16}$…

Materials Science · Physics 2013-12-17 F. Cadiz , D. Paget , V. L. Berkovits , V. P. Ulin , S. Arscott , E. Peytavit , A. C. H. Rowe

We have studied the aging effect on the dynamics of unbinding of a double stranded directed polymer in a random medium. By using the Monte Carlo dynamics of a lattice model in two dimensions, for which disorder is known to be relevant, the…

Soft Condensed Matter · Physics 2009-10-30 Somendra M. Bhattacharjee , A. Baumgärtner

We present an ultrasensitive technique for probing transient optical changes in atomically thin molybdenum disulfide (MoS$_2$) layers integrated onto silicon nitride (Si$_3$N$_4$) ring resonators. The MoS$_2$ is illuminated by a femtosecond…

The coupling of nanostructures with emitters opens ways for the realization of man-made subwavelength light emitting elements. In this article, we investigate the modification of fluorescence when an emitter is placed close to a…

Other Condensed Matter · Physics 2009-11-13 S. Kuehn , G. Mori , M. Agio , V. Sandoghdar

The vast majority of proteins are intrinsically fluorescent in the ultraviolet, thanks to the emission from their tryptophan and tyrosine amino-acid constituents. However, the protein autofluorescence quantum yields are generally very low…

We study the dynamics of hydration water/protein association in folded proteins, using lysozyme and myoglobin as examples. Extensive molecular dynamics simulations are performed to identify underlying mechanisms of the dynamical transition…

Soft Condensed Matter · Physics 2015-05-13 J. Servantie , C. Atilgan , A. R. Atilgan

Membrane phase behavior induced by the binding of curvature-inducing proteins is studied by a combination of analytical and numerical approaches. In thermal equilibrium under the detailed balance between binding and unbinding, the membrane…

Soft Condensed Matter · Physics 2022-01-03 Quentin Goutaland , Frédéric van Wijland , Jean-Baptiste Fournier , Hiroshi Noguchi

Using a structure-based coarse-grained model of proteins, we study the mechanism of unfolding of knotted proteins through heating. We find that the dominant mechanisms of unfolding depend on the temperature applied and are generally…

Biomolecules · Quantitative Biology 2017-01-23 Yani Zhao , Mateusz Chwastyk , Marek Cieplak

Signal peptide (SP) is a short peptide located in the N-terminus of proteins. It is essential to target and transfer transmembrane and secreted proteins to correct positions. Compared with traditional experimental methods to identify signal…

Artificial Intelligence · Computer Science 2023-12-15 Junbo Shen , Qinze Yu , Shenyang Chen , Qingxiong Tan , Jingcheng Li , Yu Li

The dynamics of lysozyme is probed by attaching -SCN to all alanine-residues. The 1-dimensional infrared spectra exhibit frequency shifts in the position of the maximum absorption by 4 cm$^{-1}$ which is consistent with experiments in…

Chemical Physics · Physics 2024-04-30 Sena Aydin , Seyedeh Maryam Salehi , Kai Töpfer , Markus Meuwly