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Red blood cells flowing through capillaries assume a wide variety of different shapes owing to their high deformability. Predicting the realized shapes is a complex field as they are determined by the intricate interplay between the flow…

Biological Physics · Physics 2017-11-21 Achim Guckenberger , Alexander Kihm , Thomas John , Christian Wagner , Stephan Gekle

The multi-cellular hydrodynamic interactions play a critical role in the phenomenology of blood flow in the microcirculation. A fast algorithm has been developed to simulate large numbers of cells modeled as elastic thin membranes. For red…

Fluid Dynamics · Physics 2008-10-14 Amir H. G. Isfahani , Hong Zhao , Jonathan B. Freund

We consider the motion of red blood cells and other non-spherical microcapsules dilutely suspended in a simple shear flow. Our analysis indicates that depending on the viscosity, membrane elasticity, geometry and shear rate, the particle…

Soft Condensed Matter · Physics 2015-06-25 J. M. Skotheim , T. W. Secomb

We harness the momentum of light resonating inside a micro-droplet cavity, to experimentally generate micro-flows within the envelope of the drop. We 3D map these optically induced flows by using fluorescent nanoparticles; which reveals…

Optics · Physics 2016-09-16 Daniel Bar-David , Shai Maayani , Leoplodo L. Martin , Tal Carmon

Motivated by the reported peculiar dynamics of a red blood cell in shear flow, we develop an analytical theory for the motion of a nearly--spherical fluid particle enclosed by a visco--elastic incompressible interface in linear flows. The…

Fluid Dynamics · Physics 2010-07-06 Petia M. Vlahovska , Yuan-nan Young , Gerrit Danker , Chaouqi Misbah

Two motions of oscillation and vacillating breathing (swing) of a red blood cell have been observed in bounded Poiseuille flows (Phys. Rev. E 85, 16307 (2012)). To understand such motions, we have studied the oscillating motion of a…

Fluid Dynamics · Physics 2013-04-19 Lingling Shi , Yao Yu , Tsorng-Whay Pan , Roland Glowinski

The nature of blood as a suspension of red blood cells makes computational hemodynamics a demanding task. Our coarse-grained blood model, which builds on a lattice Boltzmann method for soft particle suspensions, enables the study of the…

Soft Condensed Matter · Physics 2011-09-16 Florian Janoschek , Francesca Mancini , Jens Harting , Federico Toschi

The dynamics of single red blood cells (RBCs) determine microvascular blood flow by adapting their shape to the flow conditions in the narrow vessels. In this study, we explore the dynamics and shape transitions of RBCs on the cellular…

We combine confocal imaging, microfluidics and image analysis to record 3D-images of cells in flow. This enables us to recover the full 3D representation of several hundred living cells per minute. Whereas 3D confocal imaging has thus far…

Fluid Dynamics · Physics 2017-09-19 S. Quint , A. F. Christ , A. Guckenberger , S. Himbert , L. Kaestner , S. Gekle , C. Wagner

An improved understanding of how vortices develop and propagate under pulsatile flow can shed important light on the mixing and transport processes including the transition to turbulent regime occurring in such systems. For example, the…

Fluid Dynamics · Physics 2019-12-13 Nicasio Barrere , Javier Brum , Alexandre L'Her , Gustavo L. Sarasúa , Cecilia Cabeza

We use numerical simulations to study the dynamics of red blood cells (RBCs) in unconfined and confined Poiseuille flow. Previous numerical studies with 3D vesicles have indicated that the slipper shape observed in experiments at high…

Soft Condensed Matter · Physics 2022-03-22 Dhwanit Agarwal , George Biros

The red blood cells or erythrocytes are biconcave shaped cells and consist mostly in a membrane delimiting a cytosol with a high concentration in hemoglobin. This membrane is highly deformable and allows the cells to go through narrow…

Biological Physics · Physics 2012-06-27 Benjamin Mauroy

The dynamics of red blood cells (RBCs) in simple shear flow was studied using a theoretical approach based on three variables: a shape parameter, the inclination angle $\theta$, and phase angle $\phi$ of the membrane rotation. At high shear…

Soft Condensed Matter · Physics 2009-08-07 Hiroshi Noguchi

Recent experiments have shown that when a near-hemispherical lipid vesicle attached to a solid surface is subjected to a simple shear flow it exhibits a pattern of membrane circulation much like a dipole vortex. This is in marked contrast…

Fluid Dynamics · Physics 2012-08-14 Francis G. Woodhouse , Raymond E. Goldstein

Understanding the physics of blood is challenging due to its nature as a suspension of soft particles and the fact that typical problems involve different scales. This is valid also for numerical investigations. In fact, many computational…

Soft Condensed Matter · Physics 2011-09-16 Florian Janoschek , Federico Toschi , Jens Harting

The laboratory models of the human heart left ventricle developed in the last decades gave a valuable contribution to the comprehension of the role of the fluid dynamics in the cardiac function and to support the interpretation of the data…

Fluid Dynamics · Physics 2014-07-29 S. Fortini , G. Querzoli , S. Espa , A. Cenedese

Studies of particle motion in vortical flows have mainly focused on point-like particles, either inertial or self-propelled. This approximation assumes that the velocity field that surrounds the particle is linear. We consider an…

Fluid Dynamics · Physics 2022-01-17 Sumithra Reddy Yerasi , Rama Govindarajan , Dario Vincenzi

We report on the direct measurements of fluid flow vorticity using a spatially shaped beam with a superposition of Laguerre-Gaussian modes that reports on the rotational Doppler shift from microparticles intersecting the beam focus.…

Optics · Physics 2016-06-29 A. Ryabtsev , S. Pouya , A. Safaripour , M. Koochesfahani , M. Dantus

Blood exhibits a heterogeneous nature of hematocrit, velocity, and effective viscosity in microcapillaries. Microvascular bifurcations have a significant influence on the distribution of the blood cells and blood flow behavior. This paper…

Biological Physics · Physics 2016-02-24 Tong Wang , Uwitije Rongin , Zhongwen Xing

A simple mechanism for the confinement of red cells in the middle of narrow blood vessels is proposed. In the presence of a quadratic shear, red cells deform in such a way to loose fore-aft symmetry and to achieve a fixed orientation with…

chao-dyn · Physics 2009-10-31 Piero Olla
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