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Mild Traumatic Brain Injury (mTBI) is a significant public health problem. The most troubling symptoms after mTBI are cognitive complaints. Studies show measurable differences between patients with mTBI and healthy controls with respect to…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Tongda Xu , Xiyan Cai , Yao Wang , Xiuyuan Wang , Sohae Chung , Els Fieremans , Joseph Rath , Steven Flanagan , Yvonne W Lui

We present a method to estimate a multivariate Gaussian distribution of diffusion tensor features in a set of brain regions based on a small sample of healthy individuals, and use this distribution to identify imaging abnormalities in…

Applications · Statistics 2017-04-24 Matineh Shaker , Deniz Erdogmus , Jennifer Dy , Sylvain Bouix

Diffusion-weighted (DW) MRI measures the direction and scale of the local diffusion process in every voxel through its spectrum in q-space, typically acquired in one or more shells. Recent developments in micro-structure imaging and…

High resolution diffusion MRI (dMRI) data is often constrained by limited scanning time in clinical settings, thus restricting the use of downstream analysis techniques that would otherwise be available. In this work we develop a 3D…

Image and Video Processing · Electrical Eng. & Systems 2022-03-30 Matthew Lyon , Paul Armitage , Mauricio A. Álvarez

Diffusion weighted MRI (dMRI) provides a non invasive virtual reconstruction of the brain's white matter structures through tractography. Analyzing dMRI measures along the trajectory of white matter bundles can provide a more specific…

Quantitative Methods · Quantitative Biology 2019-06-21 Samuel St-Jean , Maxime Chamberland , Max A. Viergever , Alexander Leemans

Diffusion tensor imaging (DTI) holds significant importance in clinical diagnosis and neuroscience research. However, conventional model-based fitting methods often suffer from sensitivity to noise, leading to decreased accuracy in…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Jialong Li , Zhicheng Zhang , Yunwei Chen , Qiqi Lu , Ye Wu , Xiaoming Liu , QianJin Feng , Yanqiu Feng , Xinyuan Zhang

Diffusion MRI tractography is an important tool for identifying and analyzing the intracranial course of cranial nerves (CNs). However, the complex environment of the skull base leads to ambiguous spatial correspondence between diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Lei Xie , Qingrun Zeng , Huajun Zhou , Guoqiang Xie , Mingchu Li , Jiahao Huang , Jianan Cui , Hao Chen , Yuanjing Feng

Diffusion MRI affords valuable insights into white matter microstructures, but suffers from low signal-to-noise ratio (SNR), especially at high diffusion weighting (i.e., b-value). To avoid time-intensive repeated acquisition,…

Medical Physics · Physics 2018-07-26 Geng Chen , Yafeng Wu , Dinggang Shen , Pew-Thian Yap

Diffusion MRI is a modern neuroimaging modality with a unique ability to acquire microstructural information by measuring water self-diffusion at the voxel level. However, it generates huge amounts of data, resulting from a large number of…

Image and Video Processing · Electrical Eng. & Systems 2023-04-06 Ikram Jumakulyyev , Thomas Schultz

A new method to investigate anomalous diffusion in human brain is proposed. The method has been inspired by both the stretched-exponential model proposed by Hall and Barrick (HB) and DTI. Quantities extracted using HB method were able to…

Medical Physics · Physics 2010-04-13 S. De Santis , A. Gabrielli , M. Bozzali , B. Maraviglia , E. Macaluso , S. Capuani

The present paper introduces a method for substantial reduction of the number of diffusion encoding gradients required for reliable reconstruction of HARDI signals. The method exploits the theory of compressed sensing (CS), which…

Information Theory · Computer Science 2010-09-21 Oleg Michailovich , Yogesh Rathi , Sudipto Dolui

The importance of studying the brain microstructure is described and the existing and state of the art non-invasive methods for the investigation of the brain microstructure using Diffusion Weighted Magnetic Resonance Imaging (DWI) is…

Neural and Evolutionary Computing · Computer Science 2013-11-13 Hamed Yousefi Mesri

Tractography from high-dimensional diffusion magnetic resonance imaging (dMRI) data allows brain's structural connectivity analysis. Recent dMRI studies aim to compare connectivity patterns across subject groups and disease populations to…

Diffusion-weighted magnetic resonance imaging (DW-MRI) can be used to characterise the microstructure of the nervous tissue, e.g. to delineate brain white matter connections in a non-invasive manner via fibre tracking. Magnetic Resonance…

As the deep learning revolution marches on, masked modeling has emerged as a distinctive approach that involves predicting parts of the original data that are proportionally masked during training, and has demonstrated exceptional…

Image and Video Processing · Electrical Eng. & Systems 2025-06-25 Qinrong Cai , Yu Guan , Zhibo Chen , Dong Liang , Qiuyun Fan , Qiegen Liu

Magnetic Resonance Imaging (MRI) is a crucial diagnostic tool, but high-resolution scans are often slow and expensive due to extensive data acquisition requirements. Traditional MRI reconstruction methods aim to expedite this process by…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Emmanuelle Bourigault , Abdullah Hamdi , Amir Jamaludin

Purpose: In diffusion MRI (dMRI), the volumetric and bundle analyses of whole-brain tissue microstructure and connectivity can be severely impeded by an incomplete field-of-view (FOV). This work aims to develop a method for imputing the…

Current deep learning approaches for diffusion MRI modeling circumvent the need for densely-sampled diffusion-weighted images (DWIs) by directly predicting microstructural indices from sparsely-sampled DWIs. However, they implicitly make…

Image and Video Processing · Electrical Eng. & Systems 2021-06-25 Mengwei Ren , Heejong Kim , Neel Dey , Guido Gerig

White matter structures composed of myelinated axons in the living human brain are primarily studied by diffusion-weighted MRI (dMRI). These long-range projections are typically characterized in a two-step process: dMRI is used to estimate…

Neurons and Cognition · Quantitative Biology 2017-10-09 Matthew Cieslak , Tegan Brennan , Wendy Meiring , Lukas J. Volz , Clint Greene , Alexander Asturias , Subhash Suri , Scott T. Grafton

Historically, functional magnetic resonance imaging (fMRI) of the brain has focused primarily on gray matter, particularly the cortical gray matter and associated nuclei. However, recent work has demonstrated that functional activity in…

Medical Physics · Physics 2025-07-10 Zhiyuan Li , Kurt G. Schilling , Bennett A. Landman
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