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Combinatorial optimization is anticipated to be one of the primary use cases for quantum computation in the coming years. The Quantum Approximate Optimization Algorithm (QAOA) and Quantum Annealing (QA) can potentially demonstrate…

Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

We present a classical control mechanism for Quantum devices using Reinforcement Learning. Our strategy is applied to the Quantum Approximate Optimization Algorithm (QAOA) in order to optimize an objective function that encodes a solution…

Quantum Physics · Physics 2019-11-25 Artur Garcia-Saez , Jordi Riu

We introduce the Constraint-Enhanced Quantum Approximate Optimization Algorithm (CE-QAOA), a shallow, constraint-aware ansatz that operates inside the one-hot product space [n]^m, where m is the number of blocks and each block is…

Emerging Technologies · Computer Science 2026-01-21 Chinonso Onah , Roman Firt , Kristel Michielsen

The quantum approximate optimization algorithm (QAOA) promises to solve classically intractable computational problems in the area of combinatorial optimization. A growing amount of evidence suggests that the originally proposed form of the…

Quantum Physics · Physics 2022-05-04 Michelle Chalupnik , Hans Melo , Yuri Alexeev , Alexey Galda

Continuous-variable (CV) quantum systems offer a natural framework for continuous optimization through their infinite-dimensional Hilbert spaces. In this paper, we propose the Complex Continuous-Variable Quantum Approximate Optimization…

Quantum Physics · Physics 2026-04-30 Raneem Madani , Abdel Lisser , Zeno Toffano

The Quantum Approximate Optimization Algorithm (QAOA) is widely studied for combinatorial optimization and has achieved significant advances both in theoretical guarantees and practical performance, yet for general combinatorial…

Quantum Physics · Physics 2025-11-26 Jingheng Wang , Shengminjie Chen , Xiaoming Sun , Jialin Zhang

The Quantum Approximate Optimization Algorithm (QAOA) is a leading candidate for demonstrating quantum advantage on near-term devices, yet the physical origins of its efficacy remain poorly understood. In this work, we study QAOA for random…

Quantum Physics · Physics 2026-05-21 Mingyou Wu , Hanwu Chen

High error rates and limited fidelity of quantum gates in near-term quantum devices are the central obstacles to successful execution of the Quantum Approximate Optimization Algorithm (QAOA). In this paper we introduce an…

Quantum Physics · Physics 2022-06-16 Ruslan Shaydulin , Alexey Galda

We introduce a quantum approximate optimization algorithm (QAOA) for continuous optimization. The algorithm is based on the dynamics of a quantum system moving in an energy potential which encodes the objective function. By approximating…

Quantum Physics · Physics 2019-02-04 Guillaume Verdon , Juan Miguel Arrazola , Kamil Brádler , Nathan Killoran

The quantum approximate optimization algorithm, also known in its generalization as the quantum alternating operator ansatz, (QAOA) is a heuristic hybrid quantum-classical algorithm for finding high-quality approximate solutions to…

The Quantum Approximate Optimization Algorithm (QAOA) -- one of the leading algorithms for applications on intermediate-scale quantum processors -- is designed to provide approximate solutions to combinatorial optimization problems with…

Quantum Physics · Physics 2024-09-18 Pontus Vikstål , Laura García-Álvarez , Shruti Puri , Giulia Ferrini

Combinatorial optimization lies at the heart of numerous real-world applications. For a broad category of optimization problems, quantum computing is expected to exhibit quantum speed-up over classic computing. Among various quantum…

Quantum Physics · Physics 2025-09-23 Zixu Wang , Jack Mandell , Yangyang Xu , Jian Shi

Noise on near-term quantum devices will inevitably limit the performance of Quantum Approximate Optimization Algorithm (QAOA). One significant consequence is that the performance of QAOA may fail to monotonically improve with depth. In…

Quantum Physics · Physics 2022-07-12 Yu Pan , Yifan Tong , Shibei Xue , Guofeng Zhang

This paper proposes a novel combination of constraint encoding methods for the Quantum Approximate Optimization Ansatz (QAOA). Real-world optimization problems typically consist of multiple types of constraints. To solve these optimization…

The quantum approximate optimization algorithm (QAOA) has numerous promising applications in solving the combinatorial optimization problems on near-term Noisy Intermediate Scalable Quantum (NISQ) devices. QAOA has a quantum-classical…

Quantum Physics · Physics 2022-02-17 Xinwei Lee , Yoshiyuki Saito , Dongsheng Cai , Nobuyoshi Asai

Combinatorial optimization is among the main applications envisioned for near-term and fault-tolerant quantum computers. In this work, we consider a well-studied quantum algorithm for combinatorial optimization: the Quantum Approximate…

Quantum Physics · Physics 2020-11-12 Sami Boulebnane

This paper describes an application of the Quantum Approximate Optimisation Algorithm (QAOA) to efficiently find approximate solutions for computational problems contained in the polynomially bounded NP optimisation complexity class (NPO…

Quantum Physics · Physics 2021-07-28 Samuel Marsh , Jingbo Wang

Variational quantum algorithms are believed to be promising for solving computationally hard problems and are often comprised of repeated layers of quantum gates. An example thereof is the quantum approximate optimization algorithm (QAOA),…

The quantum approximate optimization algorithm (QAOA) has rapidly become a cornerstone of contemporary quantum algorithm development. Despite a growing range of applications, only a few results have been developed towards understanding the…

Quantum Physics · Physics 2020-03-11 V. Akshay , H. Philathong , M. E. S. Morales , J. Biamonte
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